세라마이다아제효소
알칼리성 세라마이다아제2 는 ACER2 [5] 세라마이다아제 효소 이다.
기능. ACER2/스핑고신 경로는 β1 인테그린에 의해 매개되는 인테그린 β1 서브유닛([6] 세포 접착을 조절하는 데 중요한 역할을 한다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000177076 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000038007 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Mao C, Obeid LM (September 2008). "Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate" . Biochim. Biophys. Acta . 1781 (9): 424–34. doi :10.1016/j.bbalip.2008.06.002 . PMC 2614331 PMID 18619555 . ^ Sun W, Hu W, Xu R, Jin J, Szulc ZM, Zhang G, Galadari SH, Obeid LM, Mao C (February 2009). "Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion" . FASEB J . 23 (2): 656–66. doi :10.1096/fj.08-115634 . PMC 2630785 PMID 18945876 .
외부 링크 추가 정보 Xu R, Jin J, Hu W, et al. (2006). "Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P". FASEB J . 20 (11): 1813–25. doi :10.1096/fj.05-5689com . PMID 16940153 . S2CID 20973940 . Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9" . Nature . 429 (6990): 369–74. Bibcode :2004Natur.429..369H . doi :10.1038/nature02465 . PMC 2734081 PMID 15164053 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression" . Proc. Natl. Acad. Sci. U.S.A . 101 (44): 15724–9. Bibcode :2004PNAS..10115724W . doi :10.1073/pnas.0404089101 PMC 524842 PMID 15498874 .