EGF, 라트로필린 및 7개의 트랜섬브레인 도메인 함유 단백질 1 은 접착 G 단백질 결합 수용체 계열의 래트로필린 유사 고아 수용체 다.인간에서 이 단백질 은 ELTD1 유전자 에 의해 암호화된다.[5] [6] ELTD1은 암 에서 생리학적, 병리학적,[7] 혈관신생 에 있어 역할을 하는 것으로 보인다.[8]
참고 항목 참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000162618 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000039167 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Nechiporuk T, Urness LD, Keating MT (February 2001). "ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily" . The Journal of Biological Chemistry . 276 (6): 4150–7. doi :10.1074/jbc.M004814200 PMID 11050079 . ^ "Entrez Gene: ELTD1 EGF, latrophilin and seven transmembrane domain containing 1" .^ Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, et al. (August 2013). "A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis" . Cancer Cell . 24 (2): 229–41. doi :10.1016/j.ccr.2013.06.004 . PMC 3743050 PMID 23871637 . ^ Serban F, Artene SA, Georgescu AM, Purcaru SO, Tache DE, Alexandru O, Dricu A (December 2015). "Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker" . OncoTargets and Therapy . 8 : 3767–74. doi :10.2147/OTT.S93843 . PMC 4689259 PMID 26719704 .
추가 읽기 Bjarnadóttir TK, Fredriksson R, Höglund PJ, Gloriam DE, Lagerström MC, Schiöth HB (July 2004). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics . 84 (1): 23–33. doi :10.1016/j.ygeno.2003.12.004 . PMID 15203201 . Liu T, Qian WJ, Gritsenko MA, Camp DG, Monroe ME, Moore RJ, Smith RD (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry" . Journal of Proteome Research . 4 (6): 2070–80. doi :10.1021/pr0502065 . PMC 1850943 PMID 16335952 . Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" . Genome Research . 16 (1): 55–65. doi :10.1101/gr.4039406 . PMC 1356129 PMID 16344560 .