I am Seth Frazer, an evolutionary and computational biologist. I completed my Undergraduate degree in Biology and my Master's degree in Evolutionary Biology at the University of California, Santa Barbara (UCSB). Currently, I am a first-year PhD student in the Kreshuk Lab at EMBL in Heidelberg, Germany.

My work primarily sits at the intersection of evolutionary biology, sequence analysis, and machine learning, with a heavy focus on opsin phenotype prediction.

Much of my open-source work has centered around the VisualPhysiologyDB (VPOD), where I authored tools to predict and analyze opsin phenotypes from genomic data. Here are my featured repositories (all of which are still 'live' and updates will be on-going):

• optics: An open-source Python tool that predicts the Opsin Phenotype (lambda max) from unaligned opsin amino-acid sequences.

• visual-physiology-opsin-db: A database of opsin genotype-phenotype data and machine-learning models trained to predict opsin phenotypes.

• mine_n_match: Python functions designed to mine and process sequence data directly from National Center for Biotechnology Information (NCBI) databases.

• mutagenesis_tools: A repository for mutagenesis scripts, featuring a streamlined set of scripts for site-directed mutagenesis, chimera construction, and deep-mutational scanning.

• Languages: Python, R, HTML

• Data Science: Jupyter Notebooks, Pandas, Scikit-learn, Torch

• Domain Expertise: Computational Biology, Evolutionary Biology, Bioinformatics, Machine Learning