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a DICOM file stored on a S3 store is the same DICOM file as stored on a harddrive or an a USB stick or on a http webstorage.
First you have to get access to the S3 file via some S3-api (this is out of scope of fo-dicom).
As soon as you have either a System.IO.Stream to the file or you have the content as byte-array in memory, then you can use fo-dicom to parse that file and process it. Then it is actually the very same as if the file would have been stored on your local drive.

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Answer selected by alberk8
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