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12 stars written in C
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n³ The unorthodox terminal file manager

C 21,423 796 Updated Mar 19, 2026

Toolkit for processing sequences in FASTA/Q formats

C 1,532 329 Updated Jun 1, 2025

a python package for fast random access to sequences from plain and gzipped FASTA/Q files

C 290 24 Updated Jan 16, 2026

A python extension for quick access to bigWig and bigBed files

C 240 55 Updated Jan 14, 2026

A C/C++ library for fast interval overlap queries (with a "bedtools coverage" example)

C 170 19 Updated May 28, 2024

A simple toolset for BED files (warning: CLI may change before bedtk becomes stable)

C 143 19 Updated Aug 24, 2025

TAD calling, phase imputation, 3D modeling and more for diploid single-cell Hi-C (Dip-C) and general Hi-C

C 116 17 Updated Jan 8, 2026

1D/2D indexing and querying on bgzipped text file with a pair of genomic coordinates

C 92 15 Updated Jan 28, 2025

Merging paired-end reads and removing adapters

C 46 16 Updated Nov 7, 2025

Validation and manipulation of FASTQ files, scRNA-seq barcode pre-processing and UMI quantification.

C 37 16 Updated Jun 18, 2025

Python bindings to UCSC BigWig and BigBed library

C 36 4 Updated Mar 13, 2026

A modified Ziggurat Algorithm for efficiently generating exponentially- and normally-distributed PseudoRandom Numbers (PRNs).

C 13 5 Updated May 21, 2025