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29 public repositories
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Whole-body PBPK model of midazolam as CYP3A4 DDI victim drug
Whole-body PBPK model of rifampicin as CYP3A4 and P-gp DDI perpetrator drug
Whole-body PBPK model of fluvoxamine as CYP1A2 and CYP3A4 DDI perpetrator drug
Whole-body PBPK model of digoxin as P-gp DDI victim drug
Whole-body PBPK model of alfentanil as CYP3A4 DDI victim drug
Whole-body PBPK model of clarithromycin as CYP3A4 and P-gp DDI perpetrator drug
Whole-body PBPK model of itraconazole as CYP3A4 and P-gp DDI perpetrator drug
Qualification of UGT-mediated drug-drug interactions
Whole-body PBPK model of metformin (OCT2/MATE DDI victim drug)
PBPK model of carbamazepine as CYP3A4 and CYP2B6 substrate and inducer
Whole-body PBPK model of moclobemide as a substrate and a moderate inhibitor of CYP2C19
Whole-body PBPK model of dapagliflozin
Whole-body PBPK model of ethinylestradiol as CYP1A2 DDI perpetrator drug
Whole-body PBPK model of probenecid (OAT perpetrator drug)
Modeling of published clinical Probenecid-Furosemide-DDI studies for model evaluation
Whole-body PBPK model of cimetidine (OCT2/MATE and CYP3A4 DDI perpetrator drug)
Whole-body PBPK model of rosuvastatin (OATP1B1/OATP1B3/BCRP DDI victim drug)
Whole-body PBPK model of furosemide (OAT victim drug)
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