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hbusra/README.md

Hi, I'm Busra Cagirici 👋

Senior Computational Scientist
Translational Genomics • Single-cell & Bulk RNA-seq • ML-driven Bioinformatics

I design, own, and execute end-to-end pipelines that transform high-dimensional genomics and proteomics data into reproducible, actionable insights.


🔬 Scientific & Translational Impact

I lead translational genomics projects, from data generation to reproducible pipelines, spanning transcriptomics, proteomics, and genome-scale network modeling.


🧬 Data Modalities & Expertise

  • Single-cell RNA-seq (10x Genomics, PARSE)
  • Bulk RNA-seq (differential expression, pathway analysis)
  • CyTOF / mass cytometry (immune profiling)
  • Genome & transcriptome assembly
  • Variant calling & functional annotation
  • Drug perturbation & condition-response analysis

💻 Technical Stack

Python R Perlscanpy Seurat pandas NumPy DESeq2scikit-learn XGBoost RandomForestSnakemake Docker Conda HPC (Slurm)


📫 Connect

LinkedInGoogle Scholar • 📍 San Mateo, CA

Pinned Loading

  1. ALO-scRNAseq-data-analysis ALO-scRNAseq-data-analysis Public

    viscRNA-seq analysis: SARS-CoV-2 lung organoid autophagy response (Nat Commun 2025)

    Jupyter Notebook

  2. G4Boost G4Boost Public

    G-quadruplex ML predictor (BMC Bioinf 2022) | Cited in Nature Comms & Cell

    Python 10 5

  3. mirMachine mirMachine Public

    Automated genome-wide miRNA annotation pipeline (JoVe 2021)

    Perl 1

  4. lncMachine lncMachine Public

    ML framework for genome-wide lncRNA annotation (Funct Integr Genomics 2021)

    Python 1 1

  5. PanPPI PanPPI Public

    Forked from eporetsky/PanPPI

    Pan-genome protein interaction networks (PNAS 2024, co-first author)

    Python