Stars
A place to collect papers that are related to deep learning and computational biology
swim with the flow -- CRISPR + flow cytometry screen analysis
XGBoost classifiers to predict variant classification conflict
A fast and flexible program to annotate/interpret genetic variants in VCF/BCF file
Tools for working with genomic and high throughput sequencing data.
A web application which helps us investigate the importance of features in ML-based tools for CRISPR/Cas9 gRNA efficiency prediction. This was developed as part of an MSc project in 2020.
Code used to generate DivRef, a human diversity reference for genome editing
A workflow to analyse sequence mutations in CRISPR-CAS9 targeted amplicon sequencing data
Core code for the DeepHF prediction tool
ClinVar aggregates information about genomic variation and its relationship to human health. Contact us at 'clinvar@ncbi.nlm.nih.gov' with any questions or comments.
HemTools: a collection of NGS pipelines and bioinformatic analyses
CRISPR/Cas-directed HDR genome editing suite: finds+scores gRNA targets, generates donor DNAs, & produces optimal cPCR primer designs.
Predictive models and datasets for predicting diagnostic activity from sequences.
On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
Bioinformatics analysis for CRSIPR/Cas9 off-target review
Accurate estimation of off-target editing activity from comparative NGS data
Comprehensive design of CRISPR gRNAs for nucleases and base editors