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17 stars written in C
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A parallel implementation of gzip for modern multi-processor, multi-core machines.

C 2,862 187 Updated Aug 16, 2025

A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 2,094 448 Updated Dec 12, 2025

De novo assembler for single molecule sequencing reads using repeat graphs

C 884 173 Updated May 2, 2025

Official home of genome aligner based upon notion of Cactus graphs

C 634 123 Updated Dec 16, 2025

Redbean: A fuzzy Bruijn graph approach to long noisy reads assembly

C 530 93 Updated Sep 27, 2023

Sequence-to-graph mapper and graph generator

C 464 40 Updated Aug 11, 2025

Fast and accurate de novo assembler for long reads

C 397 54 Updated May 10, 2024

Align proteins to genomes with splicing and frameshift

C 388 21 Updated Sep 20, 2025

Program for aligning DNA sequences, a pairwise aligner.

C 234 39 Updated Jun 16, 2025

Yet another k-mer analyzer

C 152 10 Updated Nov 29, 2025

Bioinformatics tools for dealing with Multiple Alignment Format (MAF) files.

C 109 32 Updated Jun 17, 2022

Identify long STRs, VNTRs, satellite DNA and other low-complexity regions in a genome

C 84 3 Updated Nov 24, 2025

PHAST

C 77 28 Updated Dec 10, 2025

DNA multiple sequence aligner, official version from Penn State's Miller Lab

C 36 7 Updated Mar 27, 2019

fork of the GPU genome aligner

C 32 2 Updated Oct 2, 2025