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Reference data: BED files, genes, transcripts, variations.

Python 88 32 Updated Nov 28, 2017

Documents from a live coding session by Christopher Wolfram related to content from the 2016 film Arrival

Mathematica 1,108 149 Updated Sep 30, 2019

🌲 An easy-to-use and scalable toolkit for genomic alteration signature (a.k.a. mutational signature) analysis and visualization in R https://shixiangwang.github.io/sigminer/reference/index.html

R 158 20 Updated Dec 25, 2025

Fast Gene Set Enrichment Analysis

R 429 72 Updated Dec 4, 2025
R 3 Updated Sep 2, 2025

ASCETIC (Agony-baSed Cancer EvoluTion InferenCe) is a novel framework for the inference of a set of statistically significant temporal patterns involving alternations in driver genes from cancer ge…

R 12 2 Updated Apr 18, 2025

Somatic point mutation caller

C++ 32 10 Updated May 6, 2025

A CNN - based pipeline for calling somatic SNP and INDEL variants without a matched normal

Python 11 3 Updated Sep 7, 2022

Somatic copy number analysis using WGS paired end wholegenome sequencing

Perl 72 17 Updated Nov 20, 2020

Battenberg R package for subclonal copynumber estimation

R 93 59 Updated Dec 8, 2025
HTML 11 6 Updated Sep 22, 2025

Validated, scalable, community developed variant calling, RNA-seq and small RNA analysis

Python 1,023 355 Updated Aug 24, 2024

An R package to time somatic mutations

R 65 22 Updated Dec 12, 2020

Create timecourse "fish plots" that show changes in the clonal architecture of tumors

R 171 46 Updated Sep 13, 2023

A software for calculating telomere length

C++ 72 28 Updated Oct 24, 2018

Tumour stratification by maximum-likelihood repeated evolution from multi-region sequencing data

R 66 26 Updated Dec 25, 2022

Model-based tumour subclonal deconvolution using population genetics

HTML 33 8 Updated Dec 2, 2025

Official code repository for GATK versions 4 and up

Java 1,897 622 Updated Dec 24, 2025

Codes used in pan-T cell analysis

R 64 19 Updated Mar 13, 2023

MutSig2CV from Lawrence et al. 2014

MATLAB 33 10 Updated Aug 18, 2020

An R package to plot maps of clone distributions in somatic evolution

R 17 6 Updated Jan 8, 2024

The analysis repository for the Open Pediatric Brain Tumor Atlas Project

HTML 105 88 Updated Jun 21, 2023

Shows how to use Shiny to demo your machine learning model or to submit Machine Learning Challenges.

R 6 18 Updated Mar 3, 2018

SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities i…

Python 172 56 Updated Nov 17, 2025

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

Python 3,580 769 Updated Oct 21, 2025

Summarize, Analyze and Visualize MAF files from TCGA or in-house studies.

R 481 224 Updated Jul 4, 2025

R data package for pre-compiled somatic mutations from TCGA cohorts and CCLE

R 98 25 Updated Oct 4, 2024

Chat with your data via AI. https://RTutor.ai

HTML 320 53 Updated Sep 5, 2025
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