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HazratMaghaz/README.md
Hazrat Maghaz GitHub Header
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πŸ‘¨β€πŸ”¬ About Me

Hi, I’m Hazrat Maghaz β€” a Bioinformatician, Computational Biologist, AI enthusiast, and research-software builder.

I work at the intersection of biology, machine learning, molecular modeling, and full-stack development. My core focus is building reproducible workflows for NGS analysis, AI-driven drug discovery, QSAR modeling, molecular docking/MD simulations, and scientific web applications.

Alongside my academic and freelance work, I am building InnoHelix and Omics Nexus with the goal of making bioinformatics tools, training, and research workflows more accessible, reproducible, and useful for students, researchers, and biotech teams.

From molecules to models β€” bridging biology, AI, and code.


πŸš€ What I Work On

Area What I Do
🧬 Bioinformatics & NGS RNA-seq analysis, differential expression, pathway enrichment, sequence analysis, and reproducible omics workflows.
πŸ’Š AI for Drug Discovery QSAR/pIC50 prediction, molecular fingerprints, ADMET-style modeling, SHAP-based interpretation, pharmacophore modeling, docking, and MD simulations.
πŸ€– Machine Learning & Deep Learning Classical ML, explainable AI, model evaluation, computer vision, medical imaging, and biological-data modeling.
πŸ’» Research Software & Web Apps Python pipelines, FastAPI backends, Next.js/React interfaces, dashboards, and bioinformatics SaaS-style tools.
πŸ§ͺ Scientific Reporting Clean project documentation, visualizations, reproducible methods, and client/research-ready reports.

πŸ› οΈ Technical Stack

Tech Stack

DESeq2 RDKit SHAP Biopython AutoDock Vina GROMACS PyMOL MOE

πŸ“Œ Featured Projects

Project Focus Description
🧬 RNA-seq Crohn’s Disease Analysis R DESeq2 GSEA Transcriptomics Differential expression and Hallmark GSEA workflow for Crohn’s Disease RNA-seq data with organized scripts, figures, and reproducible documentation.
βš—οΈ QSAR IC50 Prediction with RDKit + SHAP Python QSAR Scikit-learn SHAP AI-based QSAR pipeline for pIC50 prediction using molecular fingerprints, model comparison, applicability-domain diagnostics, and explainable modeling.
πŸ’Š hERG Pharmacophore Modeling in MOE MOE Pharmacophore Virtual Screening Pharmacophore modeling workflow for hERG inhibitor screening, including feature mapping, conformer database handling, and hit evaluation.
🐍 Bioinformatics Python Basics Python Biopython NCBI Beginner-friendly Python and Biopython scripts for sequence analysis, FASTA/FASTQ handling, k-mers, ORFs, PubMed/NCBI retrieval, and learning core bioinformatics logic.
🧠 Medical / Image Classification AI PyTorch Computer Vision Deep Learning Image-classification workflows for AI/ML learning and medical-imaging style projects. This section will be updated after the repo cleanup.
🌐 Research Web Tools Next.js FastAPI Dashboards Full-stack tools and dashboards for bioinformatics workflows, model visualization, and research pipeline deployment.

🧭 Current Focus

mindmap
  root((Hazrat Maghaz))
    Bioinformatics
      RNA-seq
      NGS pipelines
      Microbiome
      Multi-omics
    AI Drug Discovery
      QSAR
      SHAP/XAI
      Docking
      MD simulations
      Pharmacophore modeling
    Machine Learning
      Biological data
      Medical imaging
      Model evaluation
      Explainability
    Research Software
      Next.js
      FastAPI
      Dashboards
      Pipeline platforms
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πŸ“Š GitHub Analytics

Profile Details

GitHub Stats Most Commit Language

Repos per Language Productive Time

🀝 Let’s Collaborate

I’m open to research collaborations, freelance bioinformatics projects, AI/ML workflows, computational drug discovery projects, and custom scientific dashboards.


β€œBuilding reproducible research workflows from raw data to real insight.”

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  1. NGS-Crohns-Analysis-Dseq2 NGS-Crohns-Analysis-Dseq2 Public

    RNA-seq differential expression and Hallmark GSEA analysis of Crohn's Disease using DESeq2 in R.

    R

  2. QSAR-IC50-Prediction-RDKit-SHAP QSAR-IC50-Prediction-RDKit-SHAP Public

    AI-based QSAR pipeline for pIC50 prediction using molecular fingerprints, machine-learning model comparison, SHAP-ready interpretation, and applicability-domain diagnostics.

    Jupyter Notebook