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19 stars written in C
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A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 2,165 461 Updated Apr 25, 2026

Tools (written in C using htslib) for manipulating next-generation sequencing data

C 1,889 610 Updated Apr 29, 2026

Toolkit for processing sequences in FASTA/Q formats

C 1,539 328 Updated Jun 1, 2025

bedtools - the swiss army knife for genome arithmetic

C 1,030 295 Updated Mar 11, 2025

De novo assembler for single molecule sequencing reads using repeat graphs

C 921 179 Updated Apr 3, 2026

BWK awk modified for biological data

C 639 117 Updated Aug 11, 2022

Redbean: A fuzzy Bruijn graph approach to long noisy reads assembly

C 530 93 Updated Sep 27, 2023

Sequence-to-graph mapper and graph generator

C 477 40 Updated Aug 11, 2025

RAxML Next Generation: faster, easier-to-use and more flexible

C 463 68 Updated Apr 29, 2026

GenomeTools genome analysis system.

C 335 64 Updated Nov 10, 2025

Tandem Repeats Finder: a program to analyze DNA sequences

C 207 33 Updated Jan 16, 2023

Nanopore data assembler

C 168 24 Updated Mar 27, 2022

Find all significant local alignments between reads

C 141 62 Updated Jul 3, 2024

A dotplot generator for large chromosomes

C 42 5 Updated Oct 3, 2023

Integrated toolkit for analysis and evaluation of annotated genomes

C 25 10 Updated Aug 1, 2025

tandem repeat finding from erroneous long reads

C 15 5 Updated Aug 4, 2025

mdust from DFCI Gene Indices Software Tools (archived for a historical record only)

C 11 3 Updated Jan 2, 2015

semi-automatic classification and postprocessing of LTR retrotransposons

C 5 2 Updated Sep 3, 2013