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Prof. Dr.-Ing. Dr.-Ing. habil. Javier Villalba-Diez

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Prof. Dr.-Ing. Dr.-Ing. habil. Javier Villalba-Diez is a Forschungsprofessor for Quantum Computing: Mathematical Physics of Information Processing in High-Performance Computing. His work develops geometrical and topological models for quantum and hybrid-accelerated high-performance computing, with a particular focus on identifying the mathematical structures that determine the limits, robustness, complexity, and efficiency of computation.

He holds the rare distinction of having completed two PhDs at the Universidad Politécnica de Madrid, both awarded for excellence as the best doctoral theses in their respective fields. His first PhD in Engineering, Economics, and Organizational Innovation focused on Strategic Organizational Design, while his second PhD in Quantum Computational Applications for Industry 4.0 positioned his research at the intersection of quantum computing, advanced industrial systems, and future-ready digital technologies.

Driven by the question of which geometrical invariants define the boundaries of computation, Prof. Villalba-Diez translates abstract mathematical concepts into scalable computational building blocks and prototypical cyber-physical applications. His research combines quantum computing, mathematical physics, high-performance computing, artificial intelligence, and industrial digitalization, bridging rigorous theoretical foundations with applied technological implementation in cooperation with industrial and academic partners.

Alongside his research, he brings more than 20 years of international experience as a professor, consultant, and production manager in German, American, and Japanese manufacturing environments. As a Mechanical Engineer from Technische Universität München and an Industrial Engineer from UPM, he combines deep engineering expertise with strategic organizational thinking and advanced computational research.

His teaching focuses on Digitalization Strategy, Industry 5.0, Applied Mathematics, Artificial Intelligence, and Quantum Computing. His broader academic and professional mission is to empower individuals and organizations to achieve strategic goals while building trust, resilience, and technological capability.

Through his dual doctoral background, habilitation, international industrial experience, and current role as Forschungsprofessor, Prof. Villalba-Diez continues to advance the frontier between mathematical theory, quantum computation, and scalable industrial application.

• HyQCA -- Quantencomputing und hybride Quanten-Klassik-Architekturen im Schwerpunktbereich Digitale Lifeworlds & Health

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• Villalba-Díez, J., Losada-González, J.C. Exploiting quantum chaos diagnostics in QAOA for enhanced hybrid quantum classical deep learning classification. Sci Rep 16, 15744 (2026). https://doi.org/10.1038/s41598-026-51870-8
• Gish, C., Villalba-Diez, J. & Ordieres-Mere, J. A Brain-Inspired Model for Efficient Graph Learning in Human Cyber Physical Networks. Cogn Comput 18, 35 (2026). https://doi.org/10.1007/s12559-026-10574-x
• Villalba-Díez, J., González-Marcos, A., Losada-González, J.C., Ordieres-Meré, J. (2026) Squid–transmon quantum hardware simulation with deep learning for pancreatic radiotherapy image classification. Quantum Inf Process 25, 138. https://doi.org/10.1007/s11128-026-05144-x
• Villalba-Díez, J., Nuber, C., Ordieres-Meré, J. (2026) Curvature-coupled triangulated relativistic quantum computation: entanglement equilibrium, geometry registers, and discrete curvature-response relations. Quantum Studies: Mathematics Foundations 13, 21. https://doi.org/10.1007/s40509-026-00396-9
• Villalba-Díez, J., González-Marcos, A., Losada-González, J.C., Ordeires-Meré, J. (2026) Fractal photonic crystals with controlled disorder for robust 3D-integrated on-chip quantum mode localization. Optical and Quantum Electronics 58, 166. https://doi.org/10.1007/s11082-026-08741-3
• BOOK. Villalba-Díez J and Ordieres-Meré J (2026). Logistics for Engineers: Automatic Control, Network Science, and Industry 4.0. Hardcover, English edition, 21 April 2026.
• Jehnen S, Villalba-Díez J and Ordieres-Meré J (2026) FinTextSim: a domain-specific sentence-transformer for extracting predictive latent topics from financial disclosures. Frontiers in Artificial Intelligence 9:1752103. https://doi.org/10.3389/frai.2026.1752103
• Villalba-Díez, J., Ordieres-Meré, J. (2026). Standardized quantum transistor block enables differentiable learning on gait dynamics. Scientific Reports 16, 9506. https://doi.org/10.1038/s41598-026-40424-7
• Villalba-Díez, J., González-Marcos, A. (2026) Relativistic triangle–curvature computing for federated HIV-1 protein-sequence monitoring. Scientific Reports 16, 2957. https://doi.org/10.1038/s41598-025-32889-9
• Villalba-Díez, J., Ordieres-Meré, J. (2026) Triangulated relativistic quantum computation: a curvature-modulated unification of quantum and relativistic computing. Quantum Studies: Mathematics Foundations 13, 2. https://doi.org/10.1007/s40509-025-00376-5

• Villalba-Díez, J. (2025) Quantum drug discovery: a hybrid quantum graph neural network–variational quantum eigensolver framework for serine neutralization. European Physical Journal D 79, 81. https://doi.org/10.1140/epjd/s10053-025-01024-8
• Villalba-Díez, J., González-Marcos, A. (2025) Quantum-classical deep learning hybrid architecture with graphene-printed low-cost capacitive sensor for essential tremor detection. Scientific Reports 15, 20204. https://doi.org/10.1038/s41598-025-06359-1
• Villalba-Díez, J., & Ordieres-Meré, J. (2025). Quantum-enhanced signal processing via VQE for improved biomechanical feedback control. Digital Signal Processing, 157, Article 105357. https://doi.org/10.1016/j.dsp.2025.105357
• Gish, C.J., Villalba-Diez, J., Ordieres-Mere, J. (2025). Explainability as an Emergent Property of Brain-Inspired Human Cyber Physical Networks. In: Kurosu, M., Hashizume, A. (eds) Human-Computer Interaction. HCII 2025. Lecture Notes in Computer Science, vol 15767. Springer, Cham. https://doi.org/10.1007/978-3-031-93838-2_22
• Jehnen, S., Ordieres-Meré, J., & Villalba-Díez, J. (2025). FinTextSim: Enhancing financial text analysis with BERTopic. arXiv
• Sterkenburgh, T. R., Ordieres-Meré, J., & Villalba-Diez, J. (2025). Molograph 4.0: A demonstration of a non-invasive, automated system for evaluating aspects of the masticatory process in the horse. Veterinary and Animal Science, 100452. https://doi.org/10.1016/j.vas.2025.100452

• Grijalvo, M., Ordieres-Meré, J., Villalba-Díez, J., Aladro-Benito, Y., Martín-Ávila, G., Simon-Hurtado, A., & Vivaracho-Pascual, C. (2024). Sufficiency for PSS tracking gait disorders in multiple sclerosis: A managerial perspective. Heliyon, 10(9), e30001. https://doi.org/10.1016/j.heliyon.2024.e30001

• Sterkenburgh, T.R.; Villalba-Diez, J.; Ordieres-Meré, J. (2023) Socio-Technical Analysis of the Benefits and Barriers to Using a Digital Representation of the Global Horse Population in Equine Veterinary Medicine. Animals (2023), 13, 3557. https://doi.org/10.3390/ani13223557
• Ordieres-Meré, J., Gutierrez, M., & Villalba-Díez, J. (2023). Toward the industry 5.0 paradigm: Increasing value creation through the robust integration of humans and machines. Computers in Industry, 150, 103947. https://doi.org/10.1016/j.compind.2023.103947

• DIRECTOR DOCTORAL THESIS. SUMMA CUM LAUDE. Schmidt, Daniel (2022). From data and algorithms to value creation in the Industry 4.0. Thesis (Doctoral), E.T.S.I. Industriales (UPM). Download PDF Thesis Manuscript. Download PDF PhD Presentation
• Villalba-Diez, J., González-Marcos, A. & Ordieres-Meré, J. Quantum cyber-physical systems. Scientific Reports 12, 7964 (2022). https://doi.org/10.1038/s41598-022-11691-x
• Villalba-Diez, J., Ordieres-Meré, J., González-Marcos, A., & Larzabal, A. S. (2022). Quantum Deep Learning for Steel Industry Computer Vision Quality Control. 14th IFAC Workshop on Intelligent Manufacturing Systems IMS 2022, 55(2), 337–342. https://doi.org/10.1016/j.ifacol.2022.04.216
• BOOK. Villalba-Diez, J., & Ordieres Meré, J. (Eds.). (2022). JIDOKA. Integration of Human and AI within Industry 4.0 Cyber Physical Manufacturing Systems. MDPI. Download PDF
• BOOK. Villalba-Diez, J., & Ordieres Meré, J. (Eds.). (2022). Sense and Respond: Industrial Applications of Smart Sensors in Cyber-Physical Systems. MDPI. Download PDF
• DOCTORAL THESIS. SUMMA CUM LAUDE. Villalba-Diez, Javier (2022). Quantum Computation in Industry 4.0 Cyber-Physical Systems. Thesis (Doctoral), E.T.S.I. Agrónomos (UPM). Download PDF Thesis Manuscript. Download PDF PhD Presentation
• Sánchez-Herguedas, A., Mena-Nieto, A., Rodrigo-Muñoz, F., Villalba-Díez, J., Ordieres-Meré, J. (2022). Optimisation of Maintenance Policies Based on Right-Censored Failure Data Using a Semi-Markovian Approach. Sensors. 2022; 22(4):1432. https://doi.org/10.3390/s22041432
• Sánchez-Herguedas, A., Mena-Nieto, A., Rodrigo-Muñoz, F., Villalba-Diez, J., Ordieres-Meré, J. (2021) Aplicación de Enfoques Semimarkovianos a la Mejora de Políticas de Mantenimiento Predeterminado en Activos Industriales. Actas de las IV Jornadas ScienCity 2021 - Fomento de la Cultura Científica, Tecnológica y de Innovación en Ciudades Inteligentes, 17-19 Noviembre, 2021: 23-26. Huelva, Spain.
• Villalba-Diez, J., González-Marcos, A., Ordieres-Meré, J. (2022). Improvement of Quantum Approximate Optimization Algorithm for Max–Cut Problems. Sensors, 22(1). https://doi.org/10.3390/s22010244

• Villalba-Diez, J., & Ordieres-Meré, J. (2021). Human–Machine Integration in Processes within Industry 4.0 Management. Sensors, 21(17). https://doi.org/10.3390/s21175928
• Villalba-Diez, J., Molina, M., & Schmidt, D. (2021). Geometric Deep Lean Learning: Evaluation Using a Twitter Social Network. Applied Sciences, 11(15). https://doi.org/10.3390/app11156777
• Villalba-Diez, J., Gutierrez, M., Grijalvo Martín, M., Sterkenburgh, T., Losada, J. C., & Benito, R. M. (2021). Quantum JIDOKA. Integration of Quantum Simulation on a CNC Machine for In-Process Control Visualization. Sensors, 21(15). https://doi.org/10.3390/s21155031
• Villalba-Diez, J., Losada, J. C., Benito, R. M., & Schmidt, D. (2021). Industry 4.0 Quantum Strategic Organizational Design Configurations. The Case of 3 Qubits: Two Report to One. Entropy, 23(4). https://doi.org/10.3390/e23040426
• Villalba-Diez, J., Losada, J. C., Benito, R. M., & González-Marcos, A. (2021). Industry 4.0 Quantum Strategic Organizational Design Configurations. The Case of 3 Qubits: One Reports to Two. Entropy, 23(3). https://doi.org/10.3390/e23030374
• Grijalvo Martín, M., Pacios Álvarez, A., Ordieres-Meré, J., Villalba-Díez, J., & Morales-Alonso, G. (2021). New Business Models from Prescriptive Maintenance Strategies Aligned with Sustainable Development Goals. Sustainability, 13(1). https://doi.org/10.3390/su13010216

• Villalba-Diez, J., Benito, R. M., & Losada, J. C. (2020). Industry 4.0 Quantum Strategic Organizational Design Configurations. The Case of Two Qubits: One Reports to One. Sensors, 20(23), 6977. https://doi.org/10.3390/s20236977
• Villalba-Diez, J., & Zheng, X. (2020). Quantum Strategic Organizational Design: Alignment in Industry 4.0 Complex-Networked Cyber-Physical Lean Management Systems. Sensors, 20(20), 5856. https://doi.org/10.3390/s20205856
• Schmidt, D., Gevers, R., Schwiep, J., Ordieres-Meré, J., Villalba-Diez, J. (2020). Deep learning enabling quality improvement in rotogravure manufacturing. 30th International Conference on Flexible Automation and Intelligent Manufacturing (FAIM2021), 51, 330–336. https://doi.org/10.1016/j.promfg.2020.10.047
• Sun, S., Zheng, X., Villalba-Diez, J., Ordieres-Meré, J. (2020). Data Handling in Industry 4.0: Interoperability Based on Distributed Ledger Technology. Sensors, 20(11), 3046. https://doi.org/10.3390/s20113046
• Schmidt, D., Villalba Diez, J., Ordieres-Meré, J., Gevers, R., Schwiep, J., Molina, M. (2020). Industry 4.0 Lean Shopfloor Management Characterization Using EEG Sensors and Deep Learning. Sensors, 20(10), 2860. https://doi.org/10.3390/s20102860
• Villalba-Diez, J., Molina, M., Ordieres-Meré, J., Sun, S., Schmidt, D., Wellbrock, W. (2020). Geometric Deep Lean Learning: Deep Learning in Industry 4.0 Cyber–Physical Complex Networks. Sensors, 20(3), 0763. https://doi.org/10.3390/s20030763

• Wellbrock, W., Ludin, D., Villalba-Diez, J. (2019). Potentials and Success Factors of Early Supplier Integration into Own Product Development. International Journal of Business and Economic Affairs, 4(1), 1–11. https://doi.org/10.24088/IJBEA-2019-41001
• Sun, S., Zheng, X., Villalba-Diez, J., Ordieres-Meré, J. (2019). Indoor Air-Quality Data-Monitoring System: Long-Term Monitoring Benefits. Sensors, 19(19). https://doi.org/10.3390/s19194157
• Villalba-Diez, Javier, Schmidt, D., Gevers, R., Ordieres-Meré, J., Buchwitz, M., Wellbrock, W. (2019). Deep Learning for Industrial Computer Vision Quality Control in the Printing Industry 4.0. Sensors, 19(18). https://doi.org/10.3390/s19183987
• Villalba-Diez, Javier, Zheng, X., Schmidt, D., Molina, M. (2019). Characterization of Industry 4.0 Lean Management Problem-Solving Behavioral Patterns Using EEG Sensors and Deep Learning. Sensors, 19(13). https://doi.org/10.3390/s19132841
• Ordieres-Meré, J., Villalba-Diez, J., Zheng, X. (2019). Challenges and Opportunities for Publishing IIoT Data in Manufacturing as a Service Business. Procedia Manufacturing, 39, 185–193. https://doi.org/10.1016/j.promfg.2020.01.308

• Villalba-Díez, J., Ordieres-Mere, J., Molina, M., Rossner, M., & Lay, M. (2018). LEAN DENDROCHRONOLOGY: COMPLEXITY REDUCTION BY REPRESENTATION OF KPI DYNAMICS LOOKING AT STRATEGIC ORGANIZATIONAL DESIGN. Management and Production Engineering Review, 9(4), 3–9. https://doi.org/10.24425/119541

• Villalba-Diez, J., DeSanctis, I., Ordieres-Meré, J., Ciarapica, F.E. (2017). Lean Structural Network Resilience. In Cherifi, C., Cherifi, H., Karsai, M., Musolesi, M. (Eds.), Complex Networks & Its Applications VI: Proceedings of Complex Networks 2017 (The Sixth International Conference on Complex Networks and Their Applications) (pp. 609–619). Springer International Publishing. https://doi.org/10.1007/978-3-319-72150-7_49
• BOOK. Villalba-Diez, J. (2017b). The Lean Brain Theory. Complex Networked Lean Strategic Organizational Design. CRC Press. Taylor and Francis Group LLC.
• BOOK. Villalba-Diez, J. (2017a). The HOSHIN KANRI FOREST. Lean Strategic Organizational Design (1st ed.). CRC Press. Taylor and Francis Group LLC.

• Villalba-Diez, J., Ordieres-Meré, J. (2016). Improving the Management of Projects through Hoshin Kanri. Dirección y Organización, 60, 40–46.
• Villalba-Diez, J., Ordieres-Meré, J., Rubio-Valdehita, S. (2016). Lean Learning Patterns. (CPD)nA vs. KATA. Procedia CIRP, 54, 147–151. https://doi.org/10.1016/j.procir.2016.05.101
• Villalba-Diez, J., Ordieres-Meré, J. (2016). Strategic Lean Organizational Design: Towards Lean World-Small World Configurations through Discrete Dynamic Organizational Motifs. Mathematical Problems in Engineering, 2016, 1–10. https://doi.org/10.1155/2016/1825410
• DOCTORAL THESIS. SUMMA CUM LAUDE. Villalba-Diez, Javier (2016). Hoshin Kanri Forest: lean strategic organizational design. Thesis (Doctoral), E.T.S.I. Industriales (UPM). https://doi.org/10.20868/UPM.thesis.42976

• Villalba-Diez, J., Ordieres-Meré, J., Nuber, G. (2015). The HOSHIN KANRI TREE. Cross-Plant Lean Shopfloor Management. CIRP, 32, 150–155. https://doi.org/10.1016/j.procir.2015.02.120
• Villalba-Diez, J., Ordieres-Meré, J., Chudzick, H., Lopez-Rojo, P. (2015). NEMAWASHI: Attaining Value Stream alignment within Complex Organizational Networks. Procedia CIRP, 37, 134–139. https://doi.org/10.1016/j.procir.2015.08.021
• Villalba-Diez, J., Ordieres-Meré, J., Alba-Elías, F., González-Marcos, A. (2015, July 6). PMO standardization through Hoshin Kanri Improving the Management of Projects by Process Management. 9th International Conference on Industrial Engineering and Industrial Management XXI International Conference on Industrial Engineering and Operations Management International IIE Conference 2015, Aveiro, Portugal.
• Villalba-Diez, J., Ordieres-Meré, J. (2015). Improving manufacturing operational performance by standardizing process management. Transactions on Engineering Management, 62(3), 351–360. https://ieeexplore.ieee.org/document/7103303?arnumber=7103303

• The Hoshin Kanri Forest
• The Lean Brain Theory
• Sense and Respond: Industrial Applications of Smart Sensors in Cyber-Physical Systems
• JIDOKA. Integration of Human and AI within Industry 4.0 Cyber Physical Manufacturing Systems
• Quantum Computation in Industry 4.0 Cyber-Physical Systems (doctoral thesis)
• Hoshin Kanri Forest: Lean Strategic Organizational Design (doctoral thesis)
• Logistics for Engineers: Automatic Control, Network Science, and Industry 4.0

• Local Newspaper Germany. Haller Tagblatt. Vorstellung H4 (11.18)
• Local Newspaper Germany. Haller Tagblatt. eLearning Angebot (03.20)
• Press release Germany. Quantum Computation Scientific Reports (07.22)
• Interview Goethe Institut Madrid (02.23)
• Local Newspaper Germany. Haller Tagblatt. Bürger in Gefahr durch KI (03.23)
• Hochschule Heilbronn. Keynote AI und Kunst. Klara und die Sonne. (11.23)
• Local Newspaper Germany. Haller Tagblatt. Der Mensch steuerbar (03.24)
• Interview Schwatz und Weis (04.24)
• Interview Best Doctoral Tesis Prize Universidad Politécnica de Madrid (03.24)
• Local Newspaper Germany. Heilbronner Stimme. Quantum Computing (06.24)
• Local Newspaper Germany. Heilbronner Stimme. Exzellenz Rückkehr (10.24)
• Local TV Germany. L-TV. Frederick Tag (10.24)
• Volkshochschule Schwäbisch Hall. Brain Hacking (11.24)
• HHN-Bildungscampus. Rhein-Neckar Zeitung. Brain Hacking (12.24)
• Local TV Germany. L-TV. Brain Hacking (12.24)
• Heilbronner Stimme. Quantum Computing ein Meilenstein. (12.24)
• HHN. Deep Learning by Hand (04.25)
• HHN. Sex and Math (06.25)
• HHN. Kinder? Ja / Nein. (06.25)
• Heilbronner Stimme. Quantum Computing und Medizintechnik. (06.25)
• HHN. Warum Einstein für das Quanteninternet entscheidend bleibt (01.26)
• Madrid+d. Internet cuántico fiable (01.26)
• HHN Wissenschaftspreis der Thomas Gessmann-Stiftung für herausragende Forschung - Pressemitteilung (05.26)
• HHN Wissenschaftspreis der Thomas Gessmann-Stiftung für herausragende Forschung - Video (05.26)
• Heilbronner Stimme Auszeichnung für Wissenschaftliche Glanzlichter (05.26)

• Best Doctoral Thesis (01.18)
• Chess ELO 2090 (10.18)
• Public Awards
• Best Doctoral Thesis (01.24)

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