- Install the R package with
devtools::install_github('Sarah145/SarahSeq') - Load the library with
library(SarahSeq) - Run the shiny app with
SarahSeq() - When app loads, upload your snp.vcf.gz file from Dante Labs (must be gzipped, or else you'll get max upload file size exceeded error)
- Play!
Disclaimer: This whole process is very slow, especially step 1 because the package includes uk biobank data and step 4 because your vcf contains ~4 million variants. I'm not sure if there is a way to optimise any of the steps because the data is just so large but I'm open to suggestions!