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gRNAde is a Generative AI framework for inverse design of 3D RNA structure and function

Jupyter Notebook 292 25 Updated Dec 16, 2025

Differentiable, Hardware Accelerated, Molecular Dynamics

Jupyter Notebook 1,397 235 Updated Mar 28, 2026
Python 13 6 Updated Dec 14, 2025

A predictor of enzyme optimal temperature

Jupyter Notebook 14 1 Updated Mar 13, 2025

A Score-Only Adaptation of AlphaFold3 for Biomolecular Structure Evaluation

Python 118 24 Updated Jan 28, 2026

a lightweight distogram-prediction model trained via contrastive learning

Python 14 2 Updated Dec 26, 2025

A comprehensive macromolecular library

TypeScript 921 229 Updated Mar 27, 2026
Python 562 127 Updated Feb 6, 2025
Python 59 11 Updated Nov 7, 2025

open source repository

Python 146 31 Updated Nov 30, 2023

A modular framework for neural networks with Euclidean symmetry

Python 1,230 179 Updated Feb 13, 2026
Jupyter Notebook 120 12 Updated Mar 14, 2026

Arc Virtual Cell Atlas

Jupyter Notebook 509 50 Updated Feb 12, 2026

ProTrek: illuminating the Protein Universe through Trimodal Protein Language Model

Python 201 24 Updated Feb 14, 2026

Scoring function for interprotein interactions in AlphaFold2 and AlphaFold3

Python 216 29 Updated Jan 3, 2026

Generative Language Modeling for Antibody Design

Python 184 30 Updated Oct 5, 2024

BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody se…

Python 233 60 Updated May 13, 2025

Official Implementation of IgGM

Python 184 36 Updated Nov 30, 2025

Graduation Project of Bachelor

3 Updated Apr 15, 2018
Jupyter Notebook 1,519 323 Updated Nov 12, 2025

Saprot: Protein Language Model with Structural Alphabet (AA+3Di)

Python 580 68 Updated Mar 8, 2026

Making Protein Design accessible to all via Google Colab!

Python 898 214 Updated Mar 10, 2026

Official Repository for ProteinConformers: Benchmark Dataset for Simulating Protein Conformational Landscape Diversity and Plausibility

Python 9 2 Updated Dec 25, 2025
Python 2 Updated Oct 15, 2025

Reinforcement learning based cyclic peptide binder design

Ruby 13 2 Updated Jul 22, 2025
Python 137 15 Updated Jun 3, 2025

Step-by-step guide to install and configure AlphaFold 3 using a Conda Python 3.11 environment. No system-wide installations required. ✅ Miniconda setup & dependencies ✅ Repository cloning & model s…

Shell 43 6 Updated Dec 23, 2025
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