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    83 repositories

    • CREsted

      Public
      CREsted is a Python package for training sequence-based deep learning models on scATAC-seq data, for capturing enhancer code and for designing cell type-specifi…
      deep-learningsequence-modelssingle-cell-genomics
      deep-learningsequence-modelssingle-cell-genomicsscatac-seqregulatory-genomicsscverse
      Python
      •
      Other
      •12•81•5•3•Updated Sep 22, 2026Sep 22, 2026

    • pycisTopic

      Public
      pycisTopic is a Python module to simultaneously identify cell states and cis-regulatory topics from single cell epigenomics data.
      Jupyter Notebook
      •
      Other
      •21•85•60•7•Updated Sep 15, 2026Sep 15, 2026

    • TF-MINDI

      Public
      Transcription Factor Motif Instance Neighborhood Decomposition and Interpretation
      Python
      •
      Other
      •3•26•5•7•Updated Sep 11, 2026Sep 11, 2026

    • ASAP

      Public
      Modeling cis-regulatory variation in human brain enhancers across a large Parkinson's Disease cohort
      Jupyter Notebook
      •
      MIT License
      •0•3•0•0•Updated Aug 26, 2026Aug 26, 2026

    • deepSCENIC

      Public
      Deep learning for single-cell Gene Regulatory Networks
      Python
      •
      Other
      •0•3•0•0•Updated Aug 19, 2026Aug 19, 2026

    • single_cell_toolkit

      Public
      Tools for correcting single cell barcodes for various scATAC-seq techniques and creating fragment files and spltting BAM files per cluster.
      scatac-seqhydrop
      scatac-seqhydrop
      Shell
      •4•29•3•0•Updated Aug 12, 2026Aug 12, 2026

    • deepSCENIC_analyses

      Public
      Analyses scripts for "DeepSCENIC: transfer learning from sequence-to-function models enables causal gene regulatory network inference"
      Jupyter Notebook
      •0•0•0•0•Updated Jul 31, 2026Jul 31, 2026

    • SCope

      Public
      Fast visualization tool for large-scale and high dimensional single-cell data
      awscloudreactjs
      awscloudreactjsgrpcgene-expressionsingle-cellloomlarge-scale-data-visualizationgene-regulatory-network
      Python
      •
      GNU General Public License v3.0
      •15•80•98•4•Updated Jun 23, 2026Jun 23, 2026

    • GAME-DeepBICCN2-Predictor

      Public
      DeepBICCN2 Cell Type-Specific Chromatin Accessibility Predictor Container for the Genomic API for Model Evaluation (GAME)
      Python
      •0•0•0•0•Updated Jun 16, 2026Jun 16, 2026

    • GAME-BICCN-Evaluator-EnhancerLabel

      Public
      GAME container files for the BICCN evaluator (on-target enhancer cell type classification)
      Python
      •0•0•0•0•Updated Jun 3, 2026Jun 3, 2026

    • biopython

      Public
      Official git repository for Biopython (converted from CVS)
      Python
      •
      Other
      •2k•0•0•0•Updated Apr 15, 2026Apr 15, 2026

    • ctxcore

      Public
      Core functions for pycisTarget and the SCENIC tool suite
      Python
      •
      GNU General Public License v3.0
      •10•5•3•4•Updated Apr 15, 2026Apr 15, 2026

    • pycistarget

      Public
      pycistarget is a python module to perform motif enrichment analysis in sets of regions with different tools and identify high confidence TF cistromes.
      Python
      •
      Other
      •5•21•16•0•Updated Apr 14, 2026Apr 14, 2026

    • scatac_fragment_tools

      Public
      Tools for working with scATAC-seq fragment files
      fragmentsfragmentsingle-cell
      fragmentsfragmentsingle-cellscatac-seq
      Python
      •
      MIT License
      •1•7•0•1•Updated Feb 25, 2026Feb 25, 2026

    • scenicplus

      Public
      SCENIC+ is a python package to build gene regulatory networks (GRNs) using combined or separate single-cell gene expression (scRNA-seq) and single-cell chromati…
      Jupyter Notebook
      •
      Other
      •57•264•196•10•Updated Jan 16, 2026Jan 16, 2026

    • CREsted-paper

      Public
      Jupyter Notebook
      •
      MIT License
      •0•3•0•0•Updated Dec 3, 2025Dec 3, 2025

    • HyDrop_v2_paper

      Public
      To facilitate the cost-effective generation of large scATAC-seq atlases for deep learning model training, we developed a new version of the open-source microflu…
      Jupyter Notebook
      •
      MIT License
      •0•0•0•0•Updated Nov 10, 2025Nov 10, 2025

    • PUMATAC

      Public
      Pipeline for Universal Mapping of ATAC-seq
      pipelinenextflowsequencing
      pipelinenextflowsequencingatac-seqchromatin
      Nextflow
      •
      GNU General Public License v2.0
      •2•27•1•0•Updated Sep 23, 2025Sep 23, 2025

    • pySCENIC

      Public
      pySCENIC is a lightning-fast python implementation of the SCENIC pipeline (Single-Cell rEgulatory Network Inference and Clustering) which enables biologists to …
      transcription-factorstranscriptomicssingle-cell
      transcription-factorstranscriptomicssingle-cellgene-regulatory-network
      Python
      •
      GNU General Public License v3.0
      •211•638•235•5•Updated Jun 26, 2025Jun 26, 2025

    • scenicplus_core

      Public
      Collection of common algorithms and functions for all SCENIC+ related tools.
      Rust
      •0•0•0•0•Updated Jun 20, 2025Jun 20, 2025

    • create_cisTarget_databases

      Public
      Create cisTarget databases
      Python
      •7•63•38•0•Updated Jun 18, 2025Jun 18, 2025

    • mango-ingest

      Public
      Python
      •
      BSD 3-Clause "New" or "Revised" License
      •3•0•0•0•Updated Jun 12, 2025Jun 12, 2025

    • Nova-ST

      Public
      A repository containing the analysis scripts for Nova-ST data
      Jupyter Notebook
      •0•9•1•0•Updated Apr 3, 2025Apr 3, 2025

    • DeepBrain

      Public
      DeepBrain: a collection of vertebrate sequence-based enhancer models aimed at understanding brain cell type enhancer code across and within species
      genomicsevolutiondeeplearning
      genomicsevolutiondeeplearningenhancersingle-cellbrain
      Jupyter Notebook
      •
      Other
      •0•8•0•0•Updated Jan 30, 2025Jan 30, 2025

    • regulatory_regions_delineation

      Public
      Create regulatory regions delineation
      Python
      •0•1•0•0•Updated Nov 15, 2024Nov 15, 2024

    • PUMATAC_tutorial

      Public
      Jupyter Notebook
      •3•9•0•0•Updated Oct 6, 2024Oct 6, 2024

    • scforest

      Public
      scforest: a visual overview of single cell technology
      TeX
      •1•4•0•0•Updated Aug 30, 2024Aug 30, 2024

    • nextcloud_share_url_downloader

      Public
      Download files from and list content of NextCloud (password protected) share directly from the command line without needing a webbrowser.
      Shell
      •
      MIT License
      •12•28•3•0•Updated Jun 18, 2024Jun 18, 2024

    • SpatialNF

      Public
      Spatial transcriptomics NextFlow pipelines
      Python
      •
      GNU General Public License v3.0
      •2•6•1•0•Updated May 16, 2024May 16, 2024

    • SCENIC

      Public
      SCENIC is an R package to infer Gene Regulatory Networks and cell types from single-cell RNA-seq data.
      HTML
      •
      GNU General Public License v3.0
      •100•498•112•1•Updated Apr 5, 2024Apr 5, 2024
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