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An extensible, state-of-the-art framework for columnar compression, and the fastest FOSS columnar file format. Formerly at @spiraldb, now an Incubation Stage project at LFAI&Data, part of the Linux…

Rust 2,895 150 Updated Apr 29, 2026

fastVEP: High-performance Variant Effect Predictor in Rust

Rust 75 8 Updated Apr 29, 2026

Scalable annotated de Bruijn graphs for DNA indexing, alignment, and assembly

C++ 229 26 Updated Apr 29, 2026

An extremely fast Python package and project manager, written in Rust.

Rust 84,143 3,009 Updated Apr 29, 2026

v2.x of the microassembly based somatic variant caller

C++ 25 5 Updated Apr 29, 2026

The CSV magician

Rust 3,959 80 Updated Apr 29, 2026

Porting of Protein Activity and Pathway Inference to single cell and Python.

Jupyter Notebook 15 6 Updated Apr 29, 2026

Blazing-Fast Bioinformatic Operations on Python DataFrames

Python 159 30 Updated Apr 29, 2026

Open-source data framework for biology. Context and memory for datasets and models at scale. Query, trace & validate with a lineage-native lakehouse that supports bio-formats, registries & ontologi…

Python 259 24 Updated Apr 29, 2026

Precision HLA typing from next-generation sequencing data

Nextflow 79 36 Updated Apr 29, 2026

Short-read and long-read sequencing tools for diagnostics

C++ 176 35 Updated Apr 29, 2026

A reactive notebook for Python — run reproducible experiments, query with SQL, execute as a script, deploy as an app, and version with git. Stored as pure Python. All in a modern, AI-native editor.

Python 20,698 1,063 Updated Apr 29, 2026

Open Source alternative to Algolia + Pinecone and an Easier-to-Use alternative to ElasticSearch ⚡ 🔍 ✨ Fast, typo tolerant, in-memory fuzzy Search Engine for building delightful search experiences

C++ 25,751 881 Updated Apr 29, 2026

An analysis pipeline for long-reads from both PacBio and Oxford Nanopore Technologies (ONT), written in Nextflow.

Nextflow 64 22 Updated Apr 29, 2026

GitHub Action to push a subdirectory as a branch to any git repo (e.g. for GitHub Pages)

TypeScript 234 46 Updated Apr 29, 2026

Efficient and versatile C++ software program for eQTL analysis

C++ 2 Updated Apr 29, 2026

Rust/Wasm-powered SQL transpiler for more than 30 SQL dialects

Rust 797 43 Updated Apr 29, 2026

Pipeline to fetch metadata and raw FastQ files from public databases

Nextflow 189 91 Updated Apr 29, 2026

Interactive roadmaps, guides and other educational content to help developers grow in their careers.

TypeScript 353,873 43,979 Updated Apr 29, 2026

The lean application framework for Python. Build sophisticated user interfaces with a simple Python API. Run your apps in the terminal and a web browser.

Python 35,648 1,184 Updated Apr 29, 2026

A Python library for extracting structured information from unstructured text using LLMs with precise source grounding and interactive visualization.

Python 36,208 2,479 Updated Apr 29, 2026

A python library for multi omics included bulk, single cell and spatial RNA-seq analysis.

Python 967 124 Updated Apr 29, 2026

Create static executable from dynamic executable

C 414 44 Updated Apr 29, 2026

CellWhisperer bridges the gap between transcriptomics data and natural language, enabling intuitive interaction with scRNA-seq datasets

Jupyter Notebook 202 28 Updated Apr 28, 2026

AlphaGenome PyTorch port

Python 120 29 Updated Apr 28, 2026

Open-source orchestration for zero-human companies

TypeScript 60,535 10,603 Updated Apr 28, 2026

Spatial omics analysis and visualization library

Jupyter Notebook 25 3 Updated Apr 28, 2026

AnnData interoperability in R

R 169 19 Updated Apr 28, 2026

Presentation-Ready Data Summary and Analytic Result Tables

R 1,186 143 Updated Apr 28, 2026

tidyverse and ggplot2 methods for terra spatial objects

R 215 11 Updated Apr 28, 2026
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