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Production-grade engineering skills for AI coding agents.

Shell 15,751 2,014 Updated Apr 12, 2026

Hands-on AlphaFold implementation for educational purposes.

Python 114 28 Updated Apr 5, 2025

SEQUOIA: Digital profiling of cancer transcriptomes with grouped vision attention

Python 50 16 Updated Mar 24, 2026

Dreamento (DReam ENgenieering TOolbox): a Python-based software for dream engineering while monitoring/analyzing real-time EEG data.

Python 135 12 Updated Mar 18, 2024

My attempt to reproduce the workflow used by Paul Coyningham to develop an RNA immunotherapy for his dog Rosie

Python 7 Updated Mar 26, 2026

An implementation of iterative deep research using the OpenAI Agents SDK

Python 753 87 Updated Dec 27, 2025

Because `model.fit()` isn't an explanation

Python 1,268 96 Updated Mar 19, 2026

"Context engineering is the delicate art and science of filling the context window with just the right information for the next step." — Andrej Karpathy. A frontier, first-principles handbook inspi…

Python 8,725 973 Updated Feb 27, 2026

A minimal PyTorch re-implementation of AlphaFold2's model & training

Python 478 57 Updated Mar 19, 2026

🤗 Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.

Python 159,421 32,878 Updated Apr 15, 2026

Pure Python from-scratch zero-dependency implementation of Bitcoin for educational purposes

Jupyter Notebook 1,878 321 Updated Jun 21, 2021

Neural Networks: Zero to Hero

Jupyter Notebook 21,434 3,127 Updated Aug 18, 2024

Video+code lecture on building nanoGPT from scratch

Python 4,921 788 Updated Aug 13, 2024

Unifying flow matching and diffusion on Riemannian manifolds and discrete spaces, for generative deep learning.

Julia 38 5 Updated Mar 30, 2026
Julia 20 6 Updated Nov 24, 2025

An Awesome List of Open-Source Data Engineering Projects

3,143 542 Updated Oct 4, 2024

Scoring function for interprotein interactions in AlphaFold2 and AlphaFold3

Python 224 34 Updated Jan 3, 2026

Metrics for our protein design competitions.

Python 35 4 Updated Nov 1, 2024

Local Interaction Score (LIS) for structure prediction analysis

Jupyter Notebook 65 9 Updated Apr 15, 2026

code for the SE3 Transformers paper: https://arxiv.org/abs/2006.10503

Python 578 77 Updated Apr 3, 2026

Identifying peptide-receptor interactions using AlphaFold-Multimer

Jupyter Notebook 28 7 Updated Sep 12, 2023

Supercharge Open-Source AI Models

Python 349 17 Updated Apr 16, 2023

Target Sequence-Conditioned Generation of Peptide Binders via Masked Language Modeling

Python 121 24 Updated Oct 30, 2025

Protein Structure Analysis

Python 73 8 Updated Mar 21, 2026
Python 13 9 Updated Dec 23, 2025

Code for running RFdiffusion

Python 2,826 601 Updated Nov 20, 2025

The Simple Agent Development Kit.

Python 1,318 114 Updated Aug 23, 2025

Residue Level Alignment

Python 22 4 Updated Nov 21, 2024

The Fast Cross-Platform Package Manager

C++ 7,993 440 Updated Apr 14, 2026

Making Protein folding accessible to all!

Jupyter Notebook 2,724 712 Updated Mar 17, 2026
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