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Starred repositories

87 stars written in C
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Eigen tools by Nick Patterson and Alkes Price lab

C 192 63 Updated Nov 3, 2023

UCSC command line bioinformatic utilities

C 185 95 Updated Jul 31, 2024

Simple oligo analysis and primer design

C 183 44 Updated Sep 14, 2025

miscellaneous scripts for bioinformatics/genomics that dont merit their own repo.

C 182 105 Updated Nov 26, 2018

LongQC is a tool for the data quality control of the PacBio and ONT long reads.

C 175 19 Updated Dec 1, 2023

PAML is a package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood. Please report only **technical issues** on this repository (e.g., compiling, programs a…

C 175 27 Updated Sep 26, 2025

Yet another Hi-C scaffolding tool

C 163 21 Updated Nov 4, 2024

Nanopore data assembler

C 161 23 Updated Mar 27, 2022

Microassembly based somatic variant caller for NGS data

C 154 34 Updated Jun 23, 2022

Match up paired end fastq files quickly and efficiently.

C 152 33 Updated Jun 2, 2024

Yet another k-mer analyzer

C 151 10 Updated Oct 8, 2025

A genomic k-mer counter (and sequence utility) with nice features.

C 147 15 Updated Jul 4, 2025

Global alignment and alignment extension

C 139 28 Updated Jun 27, 2023

Haplotype based scans for selection

C 135 31 Updated Nov 3, 2025

Ultra-fast de novo assembler using long noisy reads

C 135 31 Updated Feb 24, 2021

Tools to work with GWAS-VCF summary statistics files

C 125 8 Updated Aug 20, 2025

The first deep learning based Nanopore simulator which can simulate the process of Nanopore sequencing.

C 123 39 Updated Oct 20, 2020

A bioinformatic toolkit to align genome assemblies into pangenome graphs

C 115 7 Updated Nov 9, 2025

Genotype and phase short tandem repeats using Illumina whole-genome sequencing data

C 101 32 Updated Feb 27, 2023

Scrappie is a technology demonstrator for the Oxford Nanopore Research Algorithms group

C 93 26 Updated Jan 13, 2022

A local-haplotagging-based small and structural variant caller

C 89 4 Updated Nov 7, 2025

EasyCodeML: A visual tool for analysis of selection using CodeML

C 83 21 Updated May 7, 2023

PHAST

C 76 27 Updated Nov 9, 2025

FALCON-Phase integrates PacBio long-read assemblies with Phase Genomics Hi-C data to create phased, diploid, chromosome-scale scaffolds

C 74 17 Updated Nov 12, 2020

Adaptive semi-global banded alignment on string graphs

C 67 5 Updated May 4, 2018

GSAlign: an ultra-fast sequence alignment algorithm for intra-species genome comparison

C 59 16 Updated Apr 24, 2024

A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 57 8 Updated Jun 4, 2024

Exact Tandem Repeat Finder (not a TRF replacement)

C 50 2 Updated Oct 22, 2019

Sequence analysis library used by Eddy/Rivas lab code

C 49 30 Updated Sep 2, 2025