This repository houses the analysis codes from the Bayesian preclinical tutorial paper led by the DIA/ASA-BIOP Nonclinical Bayesian Working Group members.

Deep learning pipeline for automated semantic segmentation and endotheliosis quantification in glomeruli histology images using transfer learning from mitochondria electron microscopy images

A 3D printable design for Bruker preclinical MRI using the 2x2 mouse or rat surface array coil for any abdominal imaging instead of brain.

Miscellaneous 3D printing designs related to preclinical imaging.

A modification on a published 3D printing design for mouse or rat brain MRI imaging.

Reproduces the results of "Cecal microbiome transplantation without antibiotic preconditioning standardizes murine microbiomes"

pose-estimation for pre-clinical drug validation

Glioblastoma (GBM) remains lethal despite multimodal therapy, with median survival under 15 months. Immunotherapy has failed in over 100 clinical trials due to three fundamental barriers: inadequate immune priming in "cold" tumors, blood–brain barrier (BBB) exclusion of therapeutics, and profound local immunosuppression.

A 3D printable design to scan on the Inveon PET/CT with 4 mice simultaneously, dynamically.