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Structural Variation Filter


Table of Contents


alt text


User Guide


Configuration

# download svf files  
$ wget https://github.com/xueyeduzhuo/svf/archive/master.zip

# decompress it on your server
$ unzip svf-master.zip

# enter svf master
$ cd svf-master

Run svf

# under svf master directory
$ ./svf.sh
or
$ python svf.py feature -b <*.bam> -c <*.vcf.gz>  -v <*.vcf.gz> -o <*_feature.txt> -g hg19 -f <*.fa>

Input

svf requires aligned files(.bam format), SV files(.vcf.gz format or .bed format) , SNV files(.vcf.gz format).

$ python svf.py pipeline -b <*.bam> -c <*.vcf.gz> -v <*.vcf.gz ...> -o <*.txt> -g hg19 -f <*.fa> 

Output

Output is generated in the current working directory by default.

$ svf ... -o <*.txt>

Requirements

  • python 2.7

    • numpy
    • pybedtools
    • pysam 0.9+
    • scikit-learn v0.19+
    • multiprocessing
    • vcf
  • bedtools 2.25.0 or later


Contact

xlwu@hit.edu.cn

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structual variation filter

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