New research highlights how parasitic infections can alter brain chemistry and behavior in humans.
Category: neuroscience – Page 4
Six-hour ‘undo’ button: GAI-17 rewinds stroke damage and may beat Alzheimer’s
Stroke kills millions, but Osaka researchers have unveiled GAI-17, a drug that halts toxic GAPDH clumping, slashes brain damage and paralysis in mice—even when given six hours post-stroke—and shows no major side effects, hinting at a single therapy that could also tackle Alzheimer’s and other tough neurological disorders.
MRI study reveals structural brain changes in children with restrictive eating disorders
In the last decade, the incidence of restrictive eating disorders in children, like anorexia-nervosa and avoidant/restrictive food intake disorders (ARFID), has doubled. These disorders have severe consequences for growing children, resulting in nutritional deficiencies and problems with bone development, statural growth and puberty. Most studies have focused on the effects of these disorders in older individuals, and little is currently known about how restrictive eating disorders affect the brain in children or what mechanisms in the brain might be responsible for this restrictive eating behavior.
To get a better understanding of how these early-onset eating disorders work in the brain, researcher Clara Moreau and her team conducted MRI brain scans on 290 children, of which 124 had been hospitalized for early-onset anorexia-nervosa (EO-AN), 50 had been hospitalized for ARFID, and 116 were children with no eating disorders. All participants were under 13 years old, and those who were hospitalized had very low body mass index (BMI) due to restrictive eating. The results were published in Nature Mental Health.
Although EO-AN and AFRID both result in low BMI and malnutrition due to restrictive eating, they are distinct disorders. EO-AN—as well as later onset anorexia-nervosa—is characterized by restrictive eating arising from a distorted body image, while restrictive eating in AFRID arises from sensory issues, such as a dislike of certain food textures, a lack of interest in food or fear of negative health consequences from food. These differences indicate that the disorders probably arise from different mechanisms in the brain.
How the Brain Increases Blood Flow on Demand
All day long, our brains carry out complicated and energy-intensive tasks such as remembering, solving problems, and making decisions.
To supply the energy these tasks require while conserving this precious fuel, the brain has evolved a system that allows it to quickly and efficiently send blood only to the areas that need it most in any given moment. This system is essential to brain function and overall health, yet how it works has remained somewhat of a mystery.
Now, a team led by researchers at Harvard Medical School has uncovered new details of how the brain moves blood to active areas in real time. Their findings are published July 16 in Cell.
In experiments in mice, the team discovered that the brain uses specialized channels in the lining of its blood vessels to communicate where blood is needed.
“This work helps us understand how you can get that super-important blood supply to the correct areas of the brain on a time scale that is useful,” said co-lead author Luke Kaplan, a research fellow in neurobiology in the Blavatnik Institute at HMS.
If confirmed in additional studies in animals and humans, the findings could be used to better understand findings on brain imaging tests such as functional MRI (fMRI). The insights may also advance understanding of neurodegenerative diseases, in which this communication system often breaks down, leading to cognitive problems.
Teilhard De Chardin; The Omega Point and the Noosphere
In this video we look at the thought of French Paleontologist, Cosmologist, WWI veteran and Jesuit Priest, Teilhard De Chardin, and his conceptions of the Omega Point and the Noosphere as articulated in his most significant work, The Phenomenon of Man.
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#integral #philosophy #evolution #consciousness #history #noosphere
Krembil Brain Institute researchers identify new model of Alzheimer’s as an autoimmune disease
(Toronto, Sept. 27, 2022) – Scientists at the Krembil Brain Institute, part of the University Health Network, have proposed a new mechanistic model (AD2) for Alzheimer’s, looking at it not as a brain disease, but as a chronic autoimmune condition that attacks the brain.
This novel research is published today, in Alzheimer’s & Dementia.
“We don’t think of Alzheimer’s as fundamentally a disease of the brain. We think of it as a disease of the immune system within the brain,” says Dr. Donald Weaver, co-Director of the Krembil Brain Institute and author of the paper.
Alzheimer’s disease, the most common form of dementia, impacts more than 50 million people around the world, with a new person being diagnosed every three seconds. Yet, despite more than 200 clinical trials in the past 30 years, there are no disease modifying therapeutics to prevent, halt or treat Alzheimer’s.
(Circa 2022 the immune function and immune molecules have been focused on recently making immunotherapy targets interesting consdering they can help remove plaques)
Elon Musk’s Neuralink microchip implanted into patient’s brain at University of Miami
Dr. Jagid and his team executed the implant on RJ just months ago.
“This device is completely invisible, you know, to anybody else that interacts with somebody who has it implanted. The other thing that makes it very unique is how it’s been miniaturized. It’s a very small device,” Dr. Jagid said.
During Neuralink’s summer update on the trial, they showed the moment one participant was able to move a cursor with his thoughts.
Consciousness, Being and Animacy; Whitehead, Bergson and the Bifurcation of Nature
An introduction to the topics of consciousness and philosophy of nature within the thought of Alfred North Whitehead and Henri Bergson.
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#consciousness #philosophy #videoessay #philosophyofscience #bergson #henribergson #animism
The Anatomy of Collective Mind Control
Unlock All The Power of Your Mind:
https://thehiddenlibrary.org/
Behind the illusion of free choice and authentic thought lies an invisible architecture shaping the collective mind. In this video, we dive deep into the anatomy of large-scale mind control. This is a form of psychic engineering that goes far beyond propaganda and mainstream media. We expose the hidden mechanisms that domesticate consciousness and manufacture consensus, from symbolic archetypes to technologies of mass emotional manipulation.
You are alive, but not awake. You walk, speak, decide, yet everything in you is mechanical. An automaton moved by impulses you do not understand. The collective mind is the machine and you are just a part of it. This video is not entertainment. It is a call to inner work. If there is still a living spark within you, it will feel this. And maybe, for the first time, you will realize you have never been free.