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St. Paul College of Ilocos Sur

This document provides information on the drug Cefuroxime, including its classification, mechanism of action, indications, contraindications, side effects, and nursing responsibilities. Cefuroxime is a second-generation cephalosporin antibiotic that works by binding to penicillin-binding proteins in bacterial cell walls to inhibit cell wall synthesis. It is indicated for various bacterial infections and should be administered intravenously over 3-5 minutes or intermittently over 15-30 minutes. Nurses should monitor for potential side effects such as diarrhea and advise patients to report severe side effects.

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Charina Aubrey
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0% found this document useful (0 votes)
84 views5 pages

St. Paul College of Ilocos Sur

This document provides information on the drug Cefuroxime, including its classification, mechanism of action, indications, contraindications, side effects, and nursing responsibilities. Cefuroxime is a second-generation cephalosporin antibiotic that works by binding to penicillin-binding proteins in bacterial cell walls to inhibit cell wall synthesis. It is indicated for various bacterial infections and should be administered intravenously over 3-5 minutes or intermittently over 15-30 minutes. Nurses should monitor for potential side effects such as diarrhea and advise patients to report severe side effects.

Uploaded by

Charina Aubrey
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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St.

Paul College of Ilocos Sur


(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Oct. 29, 2019_

Name of Classification Mechanism of Contraindications Indications Side effects and Adverse Nursing Responsibilities
Drug Action effects

Cefuroxime ( Cephalosporins, Cefuroxime, like the  Antimicrobial For the treatment of many >10%  Administer IV:
Rx) 2nd Generation penicillins, is a beta- resistance, viral different types of bacterial Diarrhea (4-11%; depends on Inject direct IV over
Brand and lactam antibiotic. By infection infections such as bronchitis, duration) 3 to 5 minutes.
Other binding to specific  Cephalosporin sinusitis, tonsillitis, ear infections, 1-10% Infuse intermittent
Names: penicillin-binding hypersensitivity, skin infections, gonorrhea, and Decreased hemoglobin or infusion over 15 to
Ceftin, proteins (PBPs) urinary tract infections. hematocrit (10%) 30 minutes.
penicillin
Zinacef located inside the Eosinophilia (7%)  Instruct patient may
hypersensitivity
Route: IV Nausea or vomiting (3-7%) experience these
bacterial cell wall, it  Renal failure,
inhibits the third and Vaginitis (<5%) side effects:
renal Transient rise in hepatic Stomach upset or
last stage of bacterial impairment transaminases (2-4%) diarrhea.
cell wall synthesis.  Colitis, diarrhea,
Cell lysis is then
Diaper rash (3%)  Advice patient to
GI disease, Increase in alkaline phosphatase
mediated by bacterial report severe
inflammatory (2%) diarrhea, difficulty
cell wall autolytic bowel disease, Thrombophlebitis (2%) breathing, unusual
enzymes such as pseudomembran Increase in lactate tiredness or fatigue,
autolysins; it is ous colitis, dehydrogenase (1%) pain at injection
possible that ulcerative colitis <1% site.
cefuroxime interferes Anemia
with an autolysin Cholestasis
inhibitor. Colitis
Dyspnea
Epidermal necrolysis
Increase in blood urea nitrogen
(BUN) and creatinine
Jaundice
Nephritis
Prolonged prothrombin time
(PT)/international normalized
ratio (INR)
Rash
Stevens-Johnson syndrome
Stomach cramps
Transient neutropenia and
leukopenia
Urticaria

St. Paul College of Ilocos Sur


(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Oct. 29, 2019_
Name of Classification Mechanism of Action Contraindications Indications Side effects and Adverse Nursing Responsibilities
Drug effects

Generic Acetaminophen The exact mechanism  caloric Paracetamol is a mild A very serious allergic  Assess patient’s fever or
Name: belongs to a of action of undernutrition. analgesic and reaction to this drug is rare. pain: type of pain,
paracetamol class of drugs acetaminophen is not  acute liver antipyretic, and is However, get medical help location, intensity,
(oral/rectal) called analgesics known. It may reduce failure. recommended for the right away if you notice any duration, temperature,
(par RA cet a (pain relievers) the production of treatment of most symptoms of a and diaphoresis.
 liver problems.
MOL) and antipyretics prostaglandins in the painful and febrile serious allergic reaction,  Assess allergic
(fever reducers).  severe renal conditions, for example,
Alternate brain. Prostaglandins including: rash, itching/swelli reactions: rash,
impairment. headache including
Name: are chemicals that ng (especially of the urticaria; if these occur,
 Shock. migraine, toothache, drug may have to be
acetaminoph cause inflammation  acetaminophen face/tongue/throat),
neuralgia, colds and discontinued.
en (a SEET a and swelling. overdose. influenza, sore throat, severe dizziness, trouble
 Teach patient to
MIN oh fen) backache, rheumatic breathing.
 Acute recognize signs of
Inflammation pain and chronic overdose:
of the Liver dysmenorrhoea. bleeding, bruising,
due to malaise, fever, sore
Hepatitis C throat.
Virus.  Tell patient to notify
prescriber for pain/
fever lasting for more
than 3 days.

St. Paul College of Ilocos Sur


(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING
Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Oct. 29, 2019_

Name of Classification Mechanism of Action Contraindications Indications Side effects and Adverse Nursing Responsibilities
Drug effects

Generic Antipasmodics The mechanism of  Prostate  Spasm in the  Constipation  Drug compatibility
Name: action of Buscopan is hypertrophy  Headache should be monitored
genitourinary
HYOSCINE Anticholinergic that it blocks the with urinary  Weakness closely in patients
BUTYLBRO muscarinic receptors retention tract requiring adjunctive
 Nausea
MIDE - found on the smooth mechanical  Spasm in the therapy
 Xerostomia  Avoid driving &
ORAL (HI- muscle walls which stenosis of GI gastrointestinal  Tachycardia
oh-seen means its blocks the operating machinery
tract tract  Urinary retention and after parenteral
BYOU-tull- action of acetylcholine  Hypersensitivit
 Spasm in the skin reaction administration.
BROH-mide) on the receptors found y to drug
biliary tract  Rarely dypsnea  Avoid strict heat
within the smooth contents  Raise side rails as a
Brand  Visual
muscle of the  Tachycardia  Colic precaution because
name: accommodation
gastrointestinal and  Myasthenia some patients become
Buscopan disturbance
urinary tract and thus gravis temporarily excited or
Adverse Effects:
reduces the spasms  Megacolon disoriented and some
and contractions. This  Parenteral  CNS: dizziness, develop amnesia or
relaxes the muscle and untreated anaphylactic become drowsy.
thus reduced the pain reactions,  Reorient patient, as
narrow-angle
from the cramps and anaphylactic shock, needed, Tolerance may
glaucoma
spasms. increased ICP, develop when therapy 
disorientation, restless is prolonged
ness, irritability,  Atropine-like toxicity
dizziness, drowsiness, may cause dose related
headache, confusion, adverse reactions.
hallucination, Individual tolerance
delirium, varies greatly
impaired memory  Overdose may cause
 CV: hypotension, curare-like effects, such
tachycardia, as respiratory paralysis.
palpitations, flushing Keep emergency
 GI: Dry mouth, equipment available.
constipation, nausea,
epigastric distress
 DERM: flushing,
dyshidrosis
 GU: Urinary
retention, urinary
hesitancy
 Resp: dyspnea,
bronchial plugging,
depressed respiration
 EENT: mydriasis,
dilated pupils, blurred
vision, photopobia,
increased intraocular
pressure, difficulty of
swallowing.

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