Esophageal Foreign Bodies: Types and Techniques For Removal: Milton T. Smith, MD Roy K.H. Wong, MD
Esophageal Foreign Bodies: Types and Techniques For Removal: Milton T. Smith, MD Roy K.H. Wong, MD
Opinion statement
 Patients with esophageal foreign bodies require prompt diagnosis and therapy. The first
 tasks are to determine the type of object, time since ingestion, location of the object,
 and the likelihood of associated complications. Patients who have evidence of complete
 esophageal occlusion or who have ingested a sharp or pointed object require urgent
 treatment due to the increased risk of complications. Button batteries are particularly
 injurious in the esophagus and should be removed immediately. Coins in the esophagus
 should also be removed; however, a brief period of observation is appropriate for coins
 in the distal esophagus, as some will pass spontaneously. Flexible endoscopy is the
 therapeutic modality of choice for most patients. The key principles for endoscopic
 management of esophageal foreign bodies are to protect the airway, to maintain control
 of the object during extraction, and to avoid causing additional damage. Endotracheal
 intubation is sometimes necessary, especially in younger children and those at higher
 risk for aspiration. The use of devices such as an esophageal overtube and a latex pro-
 tector hood may facilitate safer extraction of sharp/pointed objects. Patients with food
 impactions usually require treatment of an associated structural lesion of the esophagus.
 Introduction
Foreign body ingestions and esophageal food bolus                        including the type of object and its physical characteris-
impactions, common problems faced by clinicians, are                     tics; location of the object; age of the patient and asso-
a frequent reason for urgent endoscopy. True nonfood                     c i a t ed m e d i c a l co n d i t i o n s; t i m e e l a p s ed si n c e
foreign body ingestions are more common in children,                     ingestion; and evidence of complications such as
the majority of whom are aged 6 months to 6 years                        complete obstruction or perforation. An assessment
[1,2]. Although 80% to 90% of ingested foreign objects                   should be made as to whether the patient can be opti-
that reach the stomach will pass uneventfully without                    mally managed with available physician skills and
intervention, the remainder may become lodged in the                     whether all necessary equipment and support staff are
esophagus, placing the patient at risk for development                   immediately available.
of complications such as perforation or aspiration. The
esophagus is the most common location in the gas-                        ANATOMY AND PATHOPHYSIOLOGY
trointestinal tract for foreign body obstructions and                    Ingested foreign objects most commonly become
accounts for 75% of all impactions [3]. The true inci-                   impacted in areas that are physiologically or pathologi-
dence and overall mortality rate from ingested foreign                   cally narrowed. The four sites of physiological narrow-
objects are unknown, but deaths have been reported                       ing are the cricopharyngeus muscle of the upper
rarely [4,5]. The management of objects impacted in                      esophageal sphincter, the aortic arch, the left mainstem
the esophagus is influenced by several key factors,                      bronchus, and the lower esophageal sphincter [6••].
76     Esophageal Disease
Treatment
                                        • Flexible endoscopy is the preferred treatment modality in the majority of
                                          cases. It is helpful to plan ahead to assure that all necessary equipment is
                                          readily available (Table 3).
                                        • Successful management is influenced by the experience level and skills of
                                          the endoscopist [36]. The timing of endoscopy is dictated by the perceived
                                          risk of complications [37••].
                                        • It is critical to protect the patient’s airway from inadvertent aspiration of
                                          saliva, retained esophageal or gastric contents, and the object itself during
                                          attempted extraction.
78    Esophageal Disease
                  (Fig. 2). A major benefit of using the Roth net is that the bolus is totally encom-
                  passed within the net, so it can be grasped more securely, reducing the risk of acci-
                  dentally dropping the food in the trachea [25]. Once the bolus is ensnared, the
                  endoscope is withdrawn proximally to a level just below the cricopharyngeus. The
                  bolus is then pulled snuggly against the tip of the endoscope, suction is applied, and
                  the endoscope and ensnared food bolus are removed together as one unit. The endo-
                  scopist should be careful to avoid dislodging pieces of the bolus in the hypopharynx.
                  If this occurs they should be quickly retrieved to avoid aspiration.
                       Many endoscopists prefer to use an endoscopic suction technique [40,41].
                  A friction–fit adapter from a variceal ligation kit is fitted over the tip of the
                  endoscope. Continuous suctioning creates a vacuum and pulls the meat into the
                  adapter. This technique is highly effective for most meat impactions.
                       In situations in which the bolus has become soft and fragmented and repeated
                  intubation seems unavoidable, we prefer to insert an esophageal overtube. After
                  lubrication of the internal and external surfaces, a 44-Fr Maloney dilator is passed
                  through the tube, and the entire unit is gently guided into the esophagus; the
                  dilator is then removed. The overtube serves the dual function of protecting the
                  airway as well as facilitating esophageal intubations.
                       Several authors have advocated using a “push” technique to guide an esoph-
                  ageal food bolus into the stomach [7•,39,42,43•]. Pushing is generally considered
                  safe if the endoscope can be successfully guided around the bolus to evaluate the
                  distal esophageal anatomy. The endoscope is then withdrawn proximal to the bolus,
                  and gentle pressure is applied to carefully guide the bolus into the stomach. When
                  a hiatal hernia is present, the esophagogastric junction often takes a left turn as
                  it enters the stomach; therefore, gentle pushing from the right side of the bolus is
                  advised [25]. In situations in which the bolus cannot be passed with the endoscope,
                  one may still attempt to push gently as long as significant resistance is not encoun-
                  tered. If gentle pushing is not successful, it may be helpful to use a polypectomy
                  snare or biopsy forceps to fragment the meat into smaller pieces. Some authors have
                  also used a guidewire placed in the stomach under direct visualization to guide the
                  endoscope [39,42] or to pass small Savary dilators [39]. Vicari et al [43•] reported a
                  97% success rate using the push technique for acute esophageal food impactions.
                  Push methods require experience and good judgment and should probably be avoided
                  if multiple esophageal rings are visualized [44].
Contraindications Evidence of esophageal perforation.
   Complications Aspiration, perforation, recurrent impactions. Prospective studies are lacking.
   Special points Immediate dilation of an associated Schatzki ring or peptic stricture is appropriate
                  if there is minimal mucosal damage and the bolus has been present for a short
                  period [7•,43•]. Otherwise, the patient is generally placed on a proton-pump
                  inhibitor and a soft or liquid diet and brought back for dilation at a later date.
                  Patients should be instructed to chew carefully and avoid troublesome foods.
                       Elective endoscopy is advised in situations in which the patient experiences
                  food impaction but the bolus passes spontaneously.
80    Esophageal Disease
 Pharmacologic therapy
                                         The aim of pharmacologic therapy is to relax esophageal smooth muscle to pro-
                                         mote passage of the food bolus. Glucagon is known to cause relaxation of the
                                         lower esophageal sphincter (LES) [45]. In normal subjects, the resting LES pressure
                                         decreases by up to 60% after intravenous administration of glucagon [46]. It has
                                         little effect on the proximal esophagus.
Glucagon
                     Standard dosage 1 to 2 mg intravenously. May repeat the dose in 5 to 10 minutes if necessary.
                    Contraindications Insulinoma, pheochromocytoma, Zollinger-Ellison syndrome, and known hyper-
                                      sensitivity to glucagon.
               Main drug interactions None.
                    Main side effects Nausea and vomiting, especially with doses above 1 mg or with rapid injection
                                      (less than 1 minute). Hyperglycemia.
                       Special points The results of using glucagon to treat food impactions have been variable, most
                                      likely due to its inability to affect the diameter of strictures or rings.
                                           In one series, glucagon given at the time of endoscopy was thought to relax the
                                      esophagus to facilitate clearing the food bolus using the “push” technique [45].
                                           Other agents such as benzodiazepines, nitroglycerin, calcium channel blockers,
                                      and anticholinergics do not appear to offer a significant advantage over glucagon.
                   Cost effectiveness Available commercially as GlucaGen (Novo Nordisk, Copenhagen, Denmark). The
                                      wholesale price for a kit containing a 1 mg dose plus sterile water for reconstitution
                                      is $65 (price per Bedford Laboratories, November 2005).
                    Other treatments Other nonendoscopic, nonpharmacologic techniques used in the past have now
                                      been largely abandoned due to potential complications and the availability of
                                      safer techniques.
                                           Administration of proteolytic enzyme preparations was once popular. Solutions
                                      containing papain or chymotrypsin were given as a drink or by nasogastric instilla-
                                      tion. Although therapeutic successes were reported in early trials, two potentially
                                      life-threatening complications can occur, including transumural digestion of the
                                      esophagus and hemorrhagic pulmonary edema if the solution is aspirated. Enzyme
                                      preparations have no place in current management.
                                           Various gas-forming agents have been used to treat acute esophageal meat
                                      impactions. The ingested agents release carbon dioxide in the esophagus, which
                                      raises intraluminal pressure against a closed upper esophageal sphincter, thus forc-
                                      ing the bolus into the stomach. Agents used have included a “cocktail” of tartaric
                                      acid and bicarbonate, Carbex effervescent granules, and carbonated beverages.
                                      Several series reported success with this technique; however, esophageal perfora-
                                      tion has been reported. We do not use or recommend the use of gas-forming agents.
 Blunt objects
Endoscopic therapy
                                         Coins in the esophagus are commonly encountered, particularly in children, and
                                         should be removed to prevent damage caused by direct pressure necrosis. Perfora-
                                         tion and tracheoesophageal fistula have been reported. Pennies manufactured in
                                         the United States since 1982 are composed primarily of zinc and tend to be more
                                         corrosive than older, copper pennies.
                                             Button batteries in the esophagus are seen less frequently but require urgent
                                         removal to prevent severe caustic damage to the esophageal mucosa.
       Esophageal Foreign Bodies: Types and Techniques for Removal                Smith and Wong         81
Standard procedure Flexible endoscopy is the method of choice to extract coins from the esophagus.
                    Small children may be less cooperative and often require general anesthesia to
                    expedite removal. Because coins sometimes pass spontaneously, x-ray confirmation
                    is indicated prior to endoscopy if significant time has elapsed. Direct visualization
                    during esophageal intubation is necessary because coins are often located proxi-
                    mally. Once the coin is located in the esophagus at endoscopy, a choice is made
                    between one of several commercially available endoscopic accessories used to grasp
                    the object [47]. We prefer to use the Roth net for most coin extractions, provided
                    there is sufficient space to open the net to ensnare the coin. This may be difficult if
                    the coin is located within or very close to the cricopharyngeal sphincter. The net is
                    used to grasp the coin more securely to decrease the chance of inadvertently drop-
                    ping it during extraction. A standard polypectomy snare may also be used. The for-
                    eign body grasping forceps (rat tooth) is particularly useful in grasping the elevated
                    edges of a coin. Once the coin is securely grasped, it is pulled against the tip of the
                    endoscope, which is then slowly withdrawn. The patient should be placed in the
                    Trendelenberg position prior to extraction to lessen the risk of aspiration.
                         Button batteries may be more difficult to grasp with a snare or foreign body
                    forceps. A recent animal study by Faigel et al [36] showed the Roth net to be
                    superior to other accessories in retrieving button disc batteries.
                         If a smooth object cannot be securely grasped in the esophagus, it may be
                    possible to gently advance it into the stomach. This will usually allow reorientation
                    of the object for easier extraction.
  Contraindications Clinical evidence of esophageal perforation.
     Complications The risks are those of upper endoscopy with perhaps a greater emphasis on the risk
                    of aspiration.
     Special points Coins located in the distal esophagus will often pass spontaneously. In a recent
                    prospective study, Waltzman et al [48] found that 56% of coins in the distal third
                    of the esophagus passed spontaneously during observation compared with 27% of
                    those coins in the mid or proximal esophagus. For this reason, a period of observa-
                    tion not exceeding approximately 12 to 16 hours is warranted.
                         Rigid endoscopy for coin extraction is safe and highly successful. It provides
                    excellent visualization of the esophagus, airway protection, and control of the
                    object. The major disadvantage is the requirement for general anesthesia.
 Cost effectiveness Costs are generally those associated with an outpatient upper endoscopy. Costs are
                    higher if general anesthesia is required.
  Other treatments Nonendoscopic methods used to remove coins from the esophagus include the
                    balloon-tipped catheter method, esophageal bougienage, and the “penny
                    pincher” technique.
                         The use of balloon-tipped catheters to extract coins from the esophagus is
                    controversial. Standard Foley catheters (size 14 or 16) and similar inflatable vascu-
                    lar catheters have been used. The use of sedation for the procedure is optional.
                    Under fluoroscopic guidance, the catheter is passed orally into the esophagus to
                    a point just distal to the object. The patient is then moved from the sitting to
                    oblique prone position, and the table is turned to a steep head-down position. The
                    balloon is inflated with contrast, and the object is withdrawn while the operator
                    observes on fluoroscopy. Some series have reported success rates similar to that of
                    endoscopy. Potential complications include nosebleeds, laryngospasm, hyperpyr-
                    exia, and hypoxia [11••]. Despite favorable success rates, we do not recommend
                    this technique because there is little control of the object, and the airway is not
                    protected during extractions.
                         The bougienage technique involves using a standard esophageal dilator to
                    push a coin from the esophagus into the stomach. Bonadio et al [49] reported
                    successful use of this technique in children who had a single coin in the esopha-
                    gus for less than 24 hours. The position of the coin must be confirmed by x-ray,
                    and there must be no prior history of foreign bodies, esophageal disease, or surgi-
                    cal procedures, and no respiratory compromise. When these criteria were met, they
                    passed a single dilator without prior sedation. A success rate of 100% was reported
                    in 46 patients treated in this manner, and no complications were observed.
82    Esophageal Disease
                                              A newer method of removing coins is the “penny pincher” technique [50]. This
                                          method involves placing an endoscopic grasping forceps through a soft rubber catheter
                                          from which the end has been cut off. The device is passed orally through a bite block
                                          without sedation, using fluoroscopic observation. The prongs of the forceps are then
                                          used to grasp the edge of the coin, and the device is quickly removed. The authors
                                          reported 100% success in 19 children and no complications.
                                              Few centers have sufficient experience using these techniques, and all are “blind”
                                          in that they do not allow inspection of the mucosa. Flexible endoscopy remains the
                                          standard of care for patients with blunt foreign objects in the esophagus.
 Sharp-pointed objects
Endoscopic therapy
                                          Sharp-pointed objects lodged in the esophagus represent a medical emergency due
                                          to the fact that the risk of a complication is as high as 35% [37••]. They are often
                                          more challenging to remove. Unlike other foreign bodies such as coins, a sharp-
                                          pointed object that has reached the stomach or proximal duodenum should still be
                                          retrieved endoscopically if possible.
                                               Special precautions should be taken to avoid causing mucosal injury during
                                          extraction of these objects.
                     Standard procedure   The best principle to follow when extracting a pointed object such as a metal
                                          tack or an open safety pin from the esophagus is that the pointed end should
                                          trail, not lead. If necessary, a pointed object may be guided into the stomach
                                          first in order to achieve proper orientation before extraction. An open safety pin
                                          is best removed by grasping the hinged portion and allowing the pointed end
                                          to trail. If the pointed end is directed caudally on initial inspection, it may be
                                          grasped without reorientation.
                                               As with other types of foreign bodies, selecting the proper accessory device for
                                          extraction is important. Faigel et al [36] found that the Roth net was not useful for
                                          retrieving toothpicks (a particularly dangerous pointed object), but the polypectomy
                                          snare, Dormia basket, and foreign body forceps were highly successful. The polypec-
                                          tomy snare was also better than the Roth net for retrieving metal tacks [36].
                                               There are two techniques used to protect the esophagus from injury while sharp-
                                          pointed objects are extracted during flexible endoscopy. First, an overtube may be
                                          placed in the esophagus. The object is then grasped and pulled into the overtube,
                                          and the entire assembly is removed together as one unit. A longer overtube may be
                                          needed for sharp objects in the stomach. Second, a bell-shaped latex hood can be
                                          attached to the tip of the endoscope to retrieve sharp objects from the stomach. The
                                          bell portion of the hood is inverted back on itself with at least 2 to 3 mm of the endo-
                                          scope exposed during insertion. The object is then grasped and pulled against the tip
                                          of the endoscope. As the endoscope is withdrawn through the gastroesophageal junc-
                                          tion, the latex hood flips downward, covering the sharp object.
                                               Toothpicks, straight pins, hat pins, and similar long, pointed objects should
                                          be grasped close to the tip so that the longitudinal axis is approximately parallel
                                          to the endoscope. If necessary, the object may be pulled into an overtube prior
                                          to removal.
                      Contraindications   Clinical evidence of perforation.
                         Complications    The major potential complications of removing sharp-pointed objects include
                                          mucosal laceration and puncture, bleeding, transmural perforation, and aspiration
                                          of the object.
                         Special points   Some sharp-pointed objects are radiolucent and may not be visualized on x-rays
                                          (eg, glass, toothpick). In these settings, endoscopic intervention is indicated for
                                          diagnosis and potential therapy.
                                               Rigid endoscopy under general anesthesia is another very effective means of
                                          removing sharp-pointed objects. The mucosa and airway are protected as the
                                          object is withdrawn.
                                               Despite a higher overall complication rate, most sharp-pointed objects that
                                          reach the small intestine will pass through the GI tract without complications.
                                          The patient should be placed on a high-fiber diet, but laxatives should be avoided
                             Esophageal Foreign Bodies: Types and Techniques for Removal                   Smith and Wong            83
                                          [25]. The patient should be instructed to screen the stools, and daily x-rays should
                                          be obtained. Surgical intervention should be considered if the object has not
                                          progressed after 3 to 4 days.
                       Cost effectiveness No data are available.
Surgery
                                            Surgical intervention is more often indicated for sharp-pointed objects compared
                                            to other types of foreign bodies. In a recent series of adult patients with upper GI
                                            foreign bodies, three patients (1.1%) had objects that could not be removed endo-
                                            scopically [51]. In each case, a sharp object was impacted in the cervical esopha-
                                            gus, requiring surgery.
                                                Potential indications for surgical intervention include the following: inability
                                            to remove the object endoscopically; failure of a sharp-pointed object to progress
                                            through the intestinal tract after several days of observation; evidence of perforation;
                                            and development of other complications during observation, such as pain, fever,
                                            bleeding, and obstruction.
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This article is the current practice guideline published by the
American Society for Gastrointestinal Endoscopy. It is concise,
easy to read, and gives recommendations based upon large
series and reports from recognized experts on the subject.