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Evidence 2

1. The document sorts vocabulary words into three categories based on students' understanding: green for good understanding, yellow for some understanding, and red for not understanding. Words related to microbes, biology, and disease are included. 2. Students were asked to complete a glossary defining the yellow and red words in their list to develop their vocabulary and scientific literacy. 3. A second document discusses the HIV/AIDS drug AZT. It works by inhibiting the reverse transcriptase enzyme, reducing virus production. It is not 100% effective due to mutations, suppression of bone marrow cells, and side effects like muscle damage and nausea from mitochondrial toxicity. HIV can develop resistance over time by mutating while multiplying.

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37 views3 pages

Evidence 2

1. The document sorts vocabulary words into three categories based on students' understanding: green for good understanding, yellow for some understanding, and red for not understanding. Words related to microbes, biology, and disease are included. 2. Students were asked to complete a glossary defining the yellow and red words in their list to develop their vocabulary and scientific literacy. 3. A second document discusses the HIV/AIDS drug AZT. It works by inhibiting the reverse transcriptase enzyme, reducing virus production. It is not 100% effective due to mutations, suppression of bone marrow cells, and side effects like muscle damage and nausea from mitochondrial toxicity. HIV can develop resistance over time by mutating while multiplying.

Uploaded by

api-527267271
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Sort the following vocabulary into 3 categories:

This traffic light Red- Do not understand


work sheet this word
allowed students
to develop their Yellow- Some
vocabulary and understanding of this
scientific literacy word
skills through
Green- Good
engaging
teaching/learning understanding of this
activities. Students word
were required to
complete a
glossary list for all
the word Intracellular Complimentary binding
highlighted Yellow
and Red Pathogenicity Adaptations
Virulence Receptor molecules
Microbes Biofilms
Adhesins Toxins
Rhinovirus
Phagocyte
Antigen
Antibiotic resistance
Antigen Configuration

Complete a glossary of the yellow and red terms in your list


The HIV/AIDS drug AZT The drug AZT has been used since about 1987 in the treatment of HIV
infection. Do some research and write concise answers to the following questions.

1. Explain how the drug works to reduce the symptoms of the disease.
This Research AZT interferes with an enzyme called reverse transcriptase (RT), which is used by HIV-
activity assisted infected cells to make new viruses. Since AZT inhibits, or reduces the activity of this
students to
improve their enzyme, this drug causes HIV-infected cells to produce fewer viruses.
scientific
literacy skills
2. State reasons why the drug is not 100% successful in eliminating the virus.
because
students were It partially blocks the activity of certain human polymerase enzymes, including a
required to
mitochondrial DNA polymerase. It also suppresses the production of red blood cells,
read and
understand an neutrophils, and other cells in the bone marrow.
article on
HIV/AIDS drug
and answer the 3. Describe and state reasons for a complication or side effect of using the drug.
questions. This Taking these may cause muscle damage, fatigue, malaise, and anemia. Patients may
challenging yet
interesting also experience mild gastrointestinal intolerance, which cause nausea and vomiting. Its
writing task rare side effects include potentially life – threatening lactic acidosis and hepatic
allowed
steatosis, which stem from dysfunctional glucose metabolism by mitochondria in the
students to
improve their liver.
reading and
writing skills
4. Explain one way in which HIV can change to develop resistance to the drug.
HIV is capable of mutating while it multiplies, which makes it resistant to the drug.
Some of it develop while the patient is taking the HIV medicine. This occurs when
microevolution causes virions to become tolerant to antiretroviral treatments (ART). That is
why it is often given, either orally or intravenously, in combination with at least two or three
other drugs in order to overcome drug resistance.

Helpful Online RESOURCES about AZT Use the website below which will provide a valuable start in
your research for this Task:

https://www.britannica.com/science/AZT

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