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2569 11770 4 PB
https://doi.org/10.24294/jipd.v8i1.2569
Article
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Chang’an University, School of Economics and Management, Xi’an 710000, China
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Xuzhou University of Technology, School of Management Engineering, Xuzhou 221018, China
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School of Foreign Languages, Northwest University, Xi’an 710069, China
* Corresponding author: Jingxiao Zhang, zhangjingxiao964@126.com
CITATION Abstract: We studied the role of industry-academic collaboration (IAC) in the enhancement
Esangbedo CO, Zhang J, Esangbedo
of educational opportunities and outcomes under the digital driven Industry 4.0 using
MO, et al. (2024). The role of research and development, the patenting of products/knowledge, curriculum development,
industry-academia collaboration in and artificial intelligence as proxies for IAC. Relevant conceptual, theoretical, and empirical
enhancing educational opportunities literature were reviewed to provide a background for this research. The investigator used
and outcomes under the digital driven
Industry 4.0. Journal of
mainly principal (primary) data from a sample of 230 respondents. The primary statistics
Infrastructure, Policy and were acquired through a questionnaire. The statistics were evaluated using the structural
Development. 8(1): 2569. equation model (SEM) and Stata version 13.0 as the statistical software. The findings indicate
https://doi.org/10.24294/jipd.v8i1.25 that the direct total effect of Artificial intelligence (Aint) on educational opportunities
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(EduOp) is substantial (Coef. 0.2519916) and statistically significant (p < 0.05), implying
ARTICLE INFO that changes in Aint have a pronounced influence on EduOp. Additionally, considering the
indirect effects through intermediate variables, Research and Development (Res_dev) and
Received: 10 August 2023
Accepted: 25 September 2023 Product Patenting (Patenting) play crucial roles, exhibiting significant indirect effects on
Available online: 11 December 2023 EduOp. Res_dev exhibits a negative indirect effect (Coef = −0.009969, p = 0.000) suggesting
that increased research and development may dampen the impact of Aint on EduOp against a
COPYRIGHT priori expectation while Patenting has a positive indirect effect (Coef = 0.146621, p = 0.000),
indicating that innovation, as reflected by patenting, amplifies the effect of Aint on EduOp.
Notably, Curriculum development (Curr_dev) demonstrates a remarkable positive indirect
Copyright © 2023 by author(s).
Journal of Infrastructure, Policy and effect (Coef = 0.8079605, p = 0.000) underscoring the strong role of current development
Development is published by EnPress activities in enhancing the influence of Aint on EduOp. The study contributes to knowledge
Publisher, LLC. This work is licensed on the effective deployment of artificial intelligence, which has been shown to enhance
under the Creative Commons
educational opportunities and outcomes under the digital driven Industry 4.0 in the study area.
Attribution (CC BY) license.
https://creativecommons.org/licenses/ Keywords: Industry 4.0; industry-academia collaboration; artificial intelligence; patent
by/4.0/
development; curriculum; research and development; SEM
1. Introduction
Collaboration frameworks (Perkmann, Tartari et al., 2012) have been developed
in response to modifications of the working environments of different corporate
institutions (Cunningham and Link, 2014). Industries have always looked to
institutions of higher education as possible sources of new ideas and knowledge in
an effort to expand their knowledge base and to improve their ability to provide fresh
solutions to the complex problems confronting society (Perkmann, Neely et al.,
2011). According to Perkmann, Neely et al. (2011), in order to achieve their goals of
knowledge and innovation, a rising number of organizations are collaborating with
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academic institutions. Academics and policymakers are now more interested than
ever in the effect of university study on corporate innovation.
Universities have the potential to collaborate with businesses in a mutually
beneficial manner, thereby enhancing educational possibilities and value. This can be
achieved through the creation of improved resources for higher and advanced
education, facilitating the exchange of innovative ideas and technology transfer, and
cultivating an environment conducive to continuous learning. There exists potential
for enhanced collaboration between higher education institutions and industries, with
the aim of collectively attaining shared objectives and ensuring that graduates
possess the necessary skills and knowledge to successfully integrate into the labor
market and make meaningful contributions to global economies (Weagle et al.,
2019). This is one of the most effective strategies for technological development in
developed or industrialized countries and is a useful instrument for the effective and
efficient application of science and technology to solve social issues. There are
several ways in which these collaborations can take place, including through
cooperative research initiatives, joint curriculum creation, and joint product
patenting (product collaborations) (Lucietto et al., 2021). Schools and businesses can
work together to increase the eminence of education and design training programs by
means of collaborating. In an increasingly competitive global market, success
requires a workforce that can keep up with and learn from new markets and
technologies. Quality educational programs are clearly essential to the sustainability
of industrialization. Accordingly, there has been a shift in thinking regarding
education and industry partnership,which is now gathering steam (Weagle et al.,
2019).
Mukherji and Silberman (2021) posit that the phenomenon of industry-
academic collaboration, commonly denoted as industry-academia collaboration (IAC)
or university-industry collaboration (UIC), entails a mutually beneficial alliance
between academic establishments (such as universities and research institutions) and
industrial entities (including companies, businesses, and industries). The
establishment of partnerships between universities and industries, frequently
facilitated by government action, is widely recognized as a crucial factor in
enhancing regional and national innovation systems (O’Dwyer et al., 2023). The
purpose of this partnership is to leverage the respective experience, resources, and
capacities of the involved parties in order to promote the advancement of research,
innovation, and societal improvement in a mutually beneficial manner. Fischer et al.
(2019) argue that the establishment of partnerships between industry and academics
serves as a means to foster the flow of knowledge and expertise. Academic
institutions play a vital role in generating theoretical knowledge and conducting
research, whereas industry offer valuable practical insights and present real-world
issues. Collaborative endeavors encompass cooperative research initiatives aimed at
resolving industry-specific challenges, propelling technological advancements, and
nurturing the cultivation of innovative ideas (Alexander et al., 2020). Academic
research frequently generates novel technologies that are subsequently
commercialized through collaborative efforts, effectively bridging the gap between
academia and practical market applications. The partnership aims to synchronize
educational curriculum with the requirements of the industry, so augmenting the
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competencies of graduates and facilitating their seamless integration into the labor
market (O’Dwyer et al., 2023). Moreover, the institution provides opportunities for
internships, training programs, and workshops, hereby facilitating the exposure of
students and staff members to real-world industrial experiences.
The percentage of industry-academia collaboration in China has been increasing
in recent years. In 2019, the Chinese government issued a policy document that
called for increased collaboration between industry and academia, and set a goal of
doubling the number of industry-academia collaboration projects by 2025 (Ministry
of Science and Technology China, 2020). According to a report by the Chinese
Ministry of Science and Technology, the number of industry-academia collaboration
projects in China increased from 180,000 in 2015 to 320,000 in 2020, representing a
quantum leap. The total funding for industry-academia collaboration projects in
China also increased from 100 billion Yuan in 2015 to 300 billion Yuan in 2020 as
shown in Figure 1. The Chinese government is expected to continue to promote
industry-academia collaboration in the coming years. The government has identified
a number of key areas for industry-academia collaboration, including artificial
intelligence, big data, and semiconductors.
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various settings to machines has led to the rise of smart environments as the world
continues to enter the digital era. The educational context is one of these
environments. We hypothesize that the adoption of artificial intelligence will be a
prerequisite for achieving the desired level of educational opportunities.
China is one of the world’s leading centers of artificial intelligence (AI)
development, with its largest technology companies driving R&D. Its large populace
and varied industrial composition can generate enormous amounts of data and create
a vast market (Manyika et al., 2017). China’s future economic growth could be
contingent on the extensive adoption of artificial intelligence (AI) technologies in
R&D, product patenting, and curriculum development. The application of AI in
industry-academia collaborations has enormous economic potential for China due to
its rapidly evolving nature. The country will need to pay close attention to
developing its potential for innovation. For instance, despite the fact that Chinese
scholars have written and published more research articles on AI than American
researchers, their works have not had the same influence as those authored by
American or British authors. Furthermore, a comparable AI environment to that of
the United States, which has generated a lot more AI startup businesses than China,
is also lacking in China (Manyika et al., 2017). The American environment is vast,
creative, and diverse (including study institutions and further education colleges as
well as private corporations). It incorporates all of Silicon Valley’s well-known
strengths and has numerous advantages that are uncommon elsewhere (Biba, 2016).
In addition, current expansion of quantitative research is occurring (for example,
Kim et al., 2019; Belitski et al., 2019). It is still necessary to do quantitative research,
particularly in China, to determine the role of intermediaries (such as artificial
intelligence) in the connection between academic-industrial collaboration and
industrial innovation.
As an outcome of the rapid transformation of the technical growth of
industrialized nations, China, which is unquestionably the Asian superpower in every
field, must find a more efficient and expedient means of improving educational
prospects. To reach the current level of industry-academia collaboration in the USA,
a more effective method of enhancing educational outcomes is required in China.
The adoption of artificial intelligence enables the university and industry to make
great decisions, hence improving the speed and accuracy of strategic decision-
making processes, which will improve basic business operations and enhance the
product and services quality.
The research problem addressed in this study revolves around investigating the
transformative potential of industry–academia collaboration in the context of
enhancing educational opportunities and outcomes amidst the pervasive digital
landscape of Industry 4.0. The study recognizes the fundamental shift brought about
by Industry 4.0, driven by advanced digital technologies and artificial intelligence
(AI), and aims to comprehend how the synergy between academia and industry can
be harnessed to optimize educational prospects. It seeks to elucidate the mediating
role of AI, acting as a catalyst, in mediating the relationship between industry–
academia collaboration and educational outcomes. This research problem
encapsulates the pressing need to explore innovative strategies that align educational
systems with the rapidly evolving demands of the digital era, ultimately fostering a
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aimed at benefiting both markets and customers. The Triple Helix model is a
common way for public institutions to support university and industry collaborations.
It has been found to be a critical component in the development of regions and
countries around the world (Cai and Etzkowitz, 2020; Guimón, 2013; Dooley and
Kirk, 2007).
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(Koomsap et al., 2019), and the development of Industry 4.0 competences in Estonia
and Tanzania (Kusmin et al., 2018; Mgaiwa, 2021).
H4: There is no recursive nexus between artificial intelligence and educational
opportunities.
The recursive nexus between artificial intelligence and educational
opportunities that exist through artificial intelligence offers limitless opportunities to
students in school and industry experts (Jing, 2018; S Chen, 2018; He and Bowser,
2017). AI can assist school students in obtaining solutions to their most frequently
asked questions within seconds. This not only saves teachers a significant amount of
time but also reduces the time spent by students looking for answers or awaiting a
response to their inquiries. Artificial intelligence is a flourishing field of technology
that has the potential to change peoples’ experiences. In education, the role of AI has
been attributed to its ability to provide answers to the problems of society. This
development is currently being evaluated as a variety of scenarios (S Chen, 2018).
AI requires sophisticated infrastructure and a strong community of innovators. The
goal of the experimental artificial intelligence course conducted under the aegis of
the industry/academic partnership was to strengthen the partnership, as there is a
Granger causality effect of artificial intelligence on educational opportunities. We
believe that artificial intelligence (AI) has the power to moderate, reshape, and
transform the global technological landscape by improving educational opportunities.
AI is being broadly used across all major fields of human endeavor as well as for
national defense and security (Zhang et al., 2018). Consequently, its usage as a
moderating variable to expedite educational outcomes in industry–academia
collaboration is a positive factor in the continuing discussion over industry–academia
collaboration.
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study equally highlights the directions of the movement of the exogenous variables
as they interact to affect educational opportunities.
3. Research methodology
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Table 1 shows the Cronbach reliability of the instrument. From Table 1, the
statistics for the study’s individual variables show index values of 0.9794 for A1,
0.9800 for A2, 0.9791 for B1, 0.9799 for B2, 0.9774 for C1, 0.9781 for C2, 0.9789
for D1, and 0.9776 for D2. The Artificial Intelligence construct (Aint) index is
0.9803. The overall index of reliability is 0.9813, as shown in Table 1. According to
George and Mallery (2021), a Cronbach Alpha value of 0.70 is reliable for social
science research. In early research, a reliability of 0.70 or higher was sufficient
(Thorndike, 1995). Even with a reliability of 0.90, the standard error of measurement
is almost one-third as large as the standard deviation of the test scores, so 0.90 is the
minimum acceptable reliability, and 0.95 is the desired standard. Thus, this study’s
data collection instrument is reliable.
Table 2 shows the results of an item correlation test that was conducted to
determine whether any test item was inconsistent with the averaged behavior of the
others and could therefore be discarded. The 9-item study value scale reliability was
analyzed. The questionnaire’s Cronbach’s Alpha was 0.9813, which is acceptable.
Most items were shown to be worth keeping; deleting them would lower the alpha
value. No item’s Cronbach value was higher than the overall Cronbach Alpha value.
Deleted items would not improve the overall Cronbach Alpha statistics for any of the
study’s variables.
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early stages of university education provides a key advantage for enhancing the
educational opportunities of Chinese citizens. More males participated in the survey
than their female counterparts. Males constituted 56.52% of the sample (130
respondents), while female respondents represented 43.48% of the sample (100
respondents).
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Table 3. (Continued).
Variable Obs Mean Std. Dev. Min Max
B1 230 3.3913 0.5865397 1 4
B2 230 3.17826 0.6188146 1 4
C1 230 3.24783 0.6767309 1 4
C2 230 3.22609 0.6482879 1 4
D1 230 3.33913 0.5510919 1 4
D2 230 3.3 0.6067308 2 4
Aint 230 3.42609 0.5845294 2 4
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while a moderate RMSEA (0.05–0.10) indicates a fair fit, and a large RMSEA (>
0.10) indicates a poor fit. However, an RMSEA of 0.06 may indicate a good fit, as
suggested by Hu and Bentler (1999) in the root-mean-squared error of approximation
(RMSEA) formula. Higher values of CFI, a fit index with a range from 0 to 1,
indicate a better fit. Thus, CFI is the most popular measure of compatibility at 0.95
(Hu and Bentler, 1999; West et al., 2012). The TLI (Tucker and Lewis, 1973)
assesses the degree to which there has been a reduction in misfitting. As shown by
the data, the model fitness hypothesis cannot be supported (RMSEA = 0.048). This
means the model was fitted according to this measure of appropriateness. The CFI
and TLI values should be close to 1 to be considered acceptable; these values can be
used as criteria for model fitness (West et al., 2012). The study results show values
of CFI = 0.756 and TLI = 0.582. Evidence from these statistics suggests that the
study’s model is appropriate, and that the study’s estimates can be used to
confidently advise policymakers. Standardized root-mean-squared residual
coefficient of determination.
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Table 6. (Continued).
Eigenvalue Modulus
0 0
0 0
0 0
0 0
0 0
0 0
All eigenvalues lie inside the unit circle. SEM satisfies the stability conditions.
The path for the covariance between the exogenous variables in the model is
represented by res-dev, patent, and curr. The recursive nexus between educational
opportunities and artificial intelligence is established. The path shows that all the
exogenous variables are positive and significant predictors of the dependent
variables.
Table 7 shows the conceptual model’s SEM results. SEM models the
relationships between latent variables, not their means, to control for measurement
errors(Preacher and Hayes, 2004). In the first system of the equation, the recursive
nexus between artificial intelligence and educational opportunities [aint & edu]
indicates that educational opportunities is a positive and significant predictor of
artificial intelligence (β = 1.099941, p < 0.05). This result supports the hypothesis
that the deployment of artificial intelligence positively and significantly improves
educational opportunities. The second system of the equation presents the nexus
between the endogenous variable of educational opportunities (eduop) and a set of
three other predictor variables: research and development (res_dev), product
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LR test of model vs. saturated: chi2(21) = 1020.06, Prob > chi2 = 0.0846.
In accordance with the hypothesis, artificial intelligence is a significant
predictor of educational opportunities (β= −0.3207327, p < 0.05). This result
demonstrates a negative correlation between artificial intelligence and educational
opportunities. This may be the case due to a number of factors, including low
investment in science and technology and the absence of national strategies
(Abrahams et al., 2010). The patent was signed in accordance with a priori
expectations (β= 0.3128488, p < 0.05). Curriculum development (cur) was shown to
have a positive impact on educational opportunities in the study area (β = 0.405391,
p < 0.05), and this effect was statistically significant and consistent with a priori
expectations. This indicates that an increase of one unit in [cur] will result in a
0.4053915.
The research and development construct is significantly predicted by item A2 (β
= 0.9803375, p < 0.05), which indicates that the outcomes of R&D are freely
transferred or traded in the market. B2 is a significant predictor of product patenting
(β = 0.9009662, p < 0.05). This indicates that there is an increase in patenting due to
greater interaction between the university and industry in product development.
Curriculum development is positively and significantly affected by C2 (β =
0.9299666, p < 0.05). The D2 measure of how collaboration increases the supply of
quality workers to the industry is a strong indicator of future academic success.
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Cov (res dev, patent) and Cov (patent, curr) are positively and significantly
correlated (cov1 = 0.2720847, p = 0.000 and cov2 = 0.0630601, p = 0.001). Positive
covariance indicates that the two variables are positively related and have similar
trends over time. However, because the variables all trend in the same direction,
there is not much of a correlation between them. The sign of the covariance between
two variables specifies the direction of their linear dependence. Coefficients are
positive if there is a general trend toward an increase or decrease in both variables
(Xie and Bentler, 2003).
Specific mechanisms through which AI contributes to educational opportunities
(direct and indirect effect).
This structural equation model (SEM) Table 8 focuses on the direct effects in
the context of how artificial intelligence (Aint) mediates the relationship between the
role of industry-academia collaboration and educational opportunities (EduOp)
within the digital-driven Industry 4.0 landscape. The coefficient (Coef.) of
0.2262638 indicates a statistically significant positive direct effect of artificial
intelligence (Aint) on educational opportunities (EduOp). Aint plays a crucial role in
enhancing educational opportunities, particularly in the context of Industry 4.0. The
statistical significance (p-value < 0.001) and a 95% confidence interval ([0.1764826,
0.2760449]) suggest a robust and reliable effect. The coefficient (Coef.) of
−0.009969 suggests a statistically significant negative direct effect of educational
opportunities (EduOp) on itself. This negative effect may imply a regulatory
mechanism where an increase in educational opportunities could lead to a slight
decrease in further opportunities, possibly due to saturation or other contextual
factors. The statistical significance (p-value < 0.001) and a narrow 95% confidence
interval ([−0.010293, −0.0096451]) indicate a highly reliable effect.
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As shown in Table 10, the statistical significance (p-value < 0.001) and a 95%
confidence interval ([0.0908396, 0.1365746]) indicate a highly reliable indirect
effect. For Res_dev, the coefficient (Coef.) of −0.0010178 suggests a statistically
significant negative indirect effect of research and development (Res_dev) on
educational opportunities (EduOp). This implies that the impact of Res_dev on
EduOp is partially mediated through other variables. However, for the variable
Patenting, the coefficient (Coef.) of 0.0149697 suggests a statistically significant
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The structural equation model (SEM) total summary table provides crucial
insights into the relationship between the independent variables “Res_dev”,
“Patenting”, and “Curr_dev”, and the dependent variable “EduOp”, while
considering the mediating influence of “Aint”. The analysis reveals a multifaceted
picture of how “Aint” impacts “EduOp”. Firstly, the direct total effect of “Aint” on
“EduOp” is substantial (Coef. 0.2519916) and statistically significant, implying that
changes in “Aint” have a pronounced influence on “EduOp” without any mediation.
Additionally, considering the indirect effects through intermediate variables,
“Res_dev” and “Patenting” play crucial roles, exhibiting significant indirect effects
on “EduOp”. “Res_dev” exhibits a negative indirect effect, suggesting that increased
research and development may dampen the impact of “Aint” on “EduOp”, while
“Patenting” has a positive indirect effect, indicating that innovation, as reflected by
patenting, amplifies the effect of “Aint” on “EduOp”. Notably, “Curr_dev”
demonstrates a remarkable positive indirect effect, underscoring the strong role of
current development activities in enhancing the influence of “Aint” on “EduOp”.
4.7. Discussion
This study answers crucial research questions about how R&D, product
development, patenting, and curriculum development bring about educational
opportunities, contributing to previous research on industry–academia collaboration.
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Further, it shows the influences of causal variables and their respective directions.
The first set of equations revealed a positive and statistically significant relationship
(β = 1.099941, p < 0.05) between AI and educational possibilities. This indicates that
access to education can increase the application of AI in teamwork, and vice versa.
In the first set of equations, AI is a significant predictor of educational
opportunities, despite its negative sign (β = −0.3207327, p < 0.05). This is in contrast
to the views of Polt et al. (2001), who credited industry-academia collaboration with
increasing productivity in the workplace. The researchers found that higher levels of
innovation, productivity, competitiveness, and growth (educational opportunities) are
the desired outcomes when university–industry cooperation is used in innovation
processes (such as AI) (Argyropoulou et al., 2019). One of the biggest obstacles to
the implementation of AI in the classroom is the current state of funding and
investment in the field. Several things could be at play here. While artificial
intelligence has the potential to greatly enhance educational opportunities in China,
the country’s low investment in science and technology (such as AI) and lack of
national strategies in these areas make this goal extremely challenging to achieve, as
stated by Abrahams et al. (2010). The “innovation paradox” is not unique to Europe;
it is also present in China. This paradox describes a scenario in which high-quality
scientific outputs or inputs (like AI) have low conversion to productivity
(Argyropoulou et al., 2019; Dosi et al., 2006; Wang and Wang, 2016). The findings
indicate that while China has made some investments in AI, putting those resources
to use to improve educational opportunities has not been a top priority.
There is a connection between the exogenous variable “educational
opportunities” (eduop) and three explanatory variables: “research and development”,
“product patenting” and “curriculum development” (curr). [β > 1 p < 0.05)] . This
finding is consistent with the opinions of Hommaet et al. (2008) and Munyoki et al.
(2011), who argued that one common way that universities link up with industry to
carry out research and development collaborations is by providing opportunities for
student attachments and co-op placements in the productive sector. Student research
projects may also have input from industries if they address problems and issues that
are of immediate relevance to those sectors (Boersma et al., 2008). Similarly, Hou,
Hong, Wang et al. (2018) discovered that R&D collaboration between academic
institutions and commercial businesses boosts innovation productivity. Universities
are the key to science and technology innovation. Patents are an important indicator
of scientific and technological innovation. Positive patent signing is expected (β =
0.3128488, p < 0.05). When product patent and development increases by 1, the
endogenous variable increases by 0.3128488. In the study of Hou, Hong, Wang et al.
(2018), it was found that Chinese universities lack experience in successful industry
collaboration and market understanding, which may lead to inefficient collaborative
outcomes. Positive patenting figures indicate technological knowledge creation,
which benefits education (Griliches, 1990; Nagaoka et al., 2010). Incentives for
patenting in China have been successful (Prud’homme, 2017). This positive effect
could be due to political pressure in China via state-set patent targets tied to the
performance evaluations of managers at State Owned Enterprises and university and
government officials (Liefner et al., 2016; Cheng and Drahos, 2017).
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emphasize the intricate interplay of factors and the critical mediating role of AI,
providing valuable guidance for optimizing educational opportunities amidst the
evolving digital landscape.
Author contributions: Conceptualization of ideas and writing the first draft of the
manuscript with computational and data analysis, COE; Research supervision and
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formulated this article’s objectives and general goals, certifying the correctness of
the manuscript with funding acquisition, JZ; Re-writing the manuscript research
design, statistical work, analysis of the results, and interpretation of the results, MOE;
Questionnaire design and data curation, SDK; Funding acquisition and confirmatory
data analysis, LX. All authors have read and agreed to the published version of the
manuscript.
Additional information: Authors report all methods were carried out in accordance
with relevant guidelines and regulations of Chang’an University.
Funding: This research is supported by the National Social Science Fund projects of
China (No.20BJY010); the National Social Science Fund Post-financing projects of
China (No.19FJYB017); the China Sichuan-Tibet Railway Major Fundamental
Science Problems Special Fund (No.71942006); the China Qinghai Natural Science
Foundation (No.2020-JY-736); the List of Key Science and Technology Projects in
China’s Transportation Industry in the 2018 International Science and Technology
Cooperation Project (No.2018-GH-006 and No.2019-MS5-100); the Emerging
Engineering Education Research and Practice Project of Ministry of Education of
China (No.E-GKRWJC20202914); the Higher Education Teaching Reform Project
in Shaanxi Province, China (No.19BZ016); the Humanities and Social Sciences
Research Project of the Ministry of Education of China (21XJA752003); the Going
Global Partnership: UK-China-ASEAN, Education Partnership Initiative funded by
British Council (“Integrated Built Environment Teaching & Learning in the Joint
Curriculum Development amid Digital-Driven Industry 4.0 among China, Vietnam,
and UK” ); the International Education Research Program of Chang’an University,
China, 2022 (No. 300108221113); and the National Natural Science Foundation of
China (No. 72074191).
Data availability statement: The datasets used and/or analyzed during the current
study available from the corresponding author on reasonable request. Please contact
the corresponding author (Jingxiao Zhang: zhangjingxiao@chd.edu.cn).
Conflicts of interest: The authors declare no conflict of interest.
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