1.
30 year female reported to the opd with palpitations , dyspnoea,
koilonychia and glossitis. Investigations revealed Hb- 4 gms%, HCT-
10%, S.ferritin- 10ng/ml(normal 12-150 ng/ml)
a) What is the provisional diagnosis
b) What are the causes for this condition
c) What further laboratory investingations required to confirm your
diagnosis
2. 60 yrs old male patient was brought with history of numbness of feet,
difficulty in walking. O/E Hb- 6 gms %, platelet- 50,000cells/cu.mm TLC-
4000 , MCV-108 fl (1+5+4)
a) What is the diagnosis
b) What are the causes for this condition
c) List the laboratory investigations needed for diagnosis
d) Describe the PS and bone marrow findings in this condition
3. A 40 year old male was admitted with easy fatiguability, anorexia,
weakness, weight loss, night sweats and dragging sensation in the
abdomen due to splenomegaly. His total WBC count WAS
2,50,000/mm3 (1+5+5+4)
a. What is the probable diagnosis
b. Describe the peripheral smear with diagram of
this case
c. What are the different phases of this condition
d. Add a note on molecular basis of this condition
4. 60 year old male with history of bone pain, lytic lesion of bone and 3+
positive protein in the urine sample
a) 1.What is the diagnosis
b) 2.What are the investigations done in this case
c) 3.Describe the PS & bone marrow picture of this condition
SHORT NOTES
1. Blood and bone marrow picture in megaloblastic anemia.
2. Aplastic anemia
3. Sickle cell anemia
4. Immune thrombocytopenia
5. Hemophilia
6. Coombs test
7. Bombay blood group
8. Differentiate between myeloblast and lymhoblast
9. Hereditary spherocytosis
10. Blood transfusion reactions
11. Leukemoid reaction