strategies to enhance their academic and personal Classify and describe the skeletal

life. muscles based on architecture.

Classify skeletal muscle based on action.
NORMAL STRUCTURE
Describe the parts of a skeletal muscle.
THEORY General
Describe and differentiate the basic organization of
GROSS ANATOMY TOTAL HOURS = 15 Anatomy
innervation to skeletal, smooth, and cardiac muscle.
CODE
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC Describe the structure of Synovial Bursae
Briefly describe the applied branches of anatomy Comprehend the meaning of Hypertrophy,
Describe the "Anatomical Position" Hemiplegia, quadriplegia, paraplegia, hemiparesis
Describe the anatomical planes of body. Classify the types of blood circulation. Classify and
Describe the terms of relationship, commonly used in Introduction to exemplify various types of blood vessels.
General
F-A-001 General
Anatomy. Anatomy Describe and exemplify various types of
Anatomy
Describe the anatomical terms used specifically for anastomoses.
Limbs. Explain the importance of End Arteries
General Vascular System
F-A-007
Describe the terms related to movements. Describe the general organization of Lymphatic Anatomy (Angiology)

Describe, identify, and exemplify the general Circulation

morphological features of bones. Describe the Define the terms: Lymphoid Tissue, Tissue Fluid,
developmental classification of bones. Lymphatic, Capillaries, Lymph and Lymphatic Vessels
Describe the regional classification of bones. Define the terms; Lymphangitis, Lymphadenitis.
Describe the morphological classification of bones. Define neuron.
Describe and exemplify Sesamoid, Pneumatic, Describe the anatomical structure of a neuron. General
Wormian and Heterotopic bones. Classify neurons based on morphology with Anatomy
Describe the general features of adult typical long examples.
bone. General Bones
F-A-002 Classify neurons based on function. Describe the
Anatomy (Osteology)
Describe the types of epiphyses components of the central nervous system.
Discuss the general concept of ossification (primary Describe the components of the peripheral nervous Nervous Tissue
F-A-008
and secondary centers and rule of ossification) system. (Neurology)
Describe the relationship of growing end of bones Name the supporting cells (neuroglia) of the central General
with the direction of nutrient foramen nervous system. Anatomy
Describe the blood supply of various types of bones Describe the structure and functions of the neuroglia
Describe the salient features of common types of of the central nervous system.
fractures and basic concept of healing of fracture. Enumerate the supporting cells (neuroglia) of the
F-A-003 Describe the general features of cartilage and its General Cartilage peripheral nervous system.

90 92

importance in gross anatomy. Anatomy (Chondrology) Describe the structure and functions of the neuroglia
Describe the subtypes and gross features of Hyaline, of the peripheral nervous system.
elastic and fibro Cartilage. Differentiate the three Enlist the cranial nerves I to XII
types of cartilages Describe the types of nerve fibers carried by and
Describe and exemplify the structural classification of distribution of the cranial nerves.
Joints (synovial, cartilaginous & fibrous) along with Describe the formation, types of modalities carried by,
their sub-classification. and distribution of the spinal nerves.
Describe the components and characteristic features Explain Dermatome (s)
of a Synovial Joints. Describe the blood supply, General Joints
F-A-004 Explain Myotome (s)
Anatomy (Arthrology)
innervation of Synovial Joints, cartilaginous joints, Describe the formation of Plexuses. Differentiate
and fibrous joints. List the factors stabilizing a between Somatic and Visceral nervous system.
synovial joint. Define Receptors
Define common joint injuries and diseases Describe the functions of receptors.
Describe the structure and function of Skin on the Classify sensory receptors based on modality (with
basis of its two layers; Epidermis and Dermis location)
Describe the structure of Hair as an appendage of Define Effectors
skin. Describe the functions of effectors.
Describe the structure of Nail as an appendage of Describe ANS (Autonomic Nervous System) and
skin. differentiate between sympathetic and
Describe the structure of Sweat and Sebaceous parasympathetic nervous system
Glands General Integumentary
F-A-005 Identify displacement of fracture segments of the
Anatomy System
Describe the structure and function of Superficial bone Integrate with Imaging in
F-A-009
Radiology Anatomy
Fascia Identify dislocation of joints
Describe the structure, function, and modifications of
EMBRYOLOGY & POST-NATAL
TOTAL HOURS = 25
Deep Fascia DEVELOPMENT
CODE
Describe important clinical correlates of skin (skin SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC
infections, sebaceous cyst, skin burns and skin Define Chromosome Theory of inheritance
grafting) Enlist different stages of Mitosis and Meiosis
Classify and describe Muscle Tissue based on Compare and contrast Mitosis and Meiosis Cell division
Structure, Function and Development F-A-010 Enlist the numerical chromosomal anomalies Embryology
and
General Muscle Tissue Chromosomal
F-A-006 Describe Somatic and Visceral Muscles Describe the anatomical basis for numerical abnormalities
Anatomy (Myology)
Describe and differentiate the Red and White Variety chromosomal abnormalities. Describe the clinical
of Skeletal Muscles presentation of numerical chromosomal abnormalities

91 93
 & justify them embryologically Describe the Abnormal implantation/ extra uterine
Describe the clinical presentation of structural implantations.
chromosomal abnormalities and justify them Define the Molar pregnancy.
embryologically. Describe the formation of amniotic cavity, embryonic
Describe the embryological basis for mosaicism disc, and umbilical vesicle Describe the formation of
Describe the embryological basis for teratoma chorionic sac.
Describe Concept of Gene Mutation. Enlist common Describe the Establishment of uteroplacental Utero-Placental
F-A-022
diagnostic techniques for identifying genetic circulation. circulation
abnormalities. Describe the Formation & fate of primitive streak.
Describe the Process of spermatogenesis and Draw a concept map highlighting the sequence of
spermiogenesis Gametogenesis events responsible for transformation of bilaminar
F-A-011 Embryology Spermatogenesis
Describe the embryological basis for Abnormal germ disc into trilaminar germ disc. Embryology
gametes F-A-023 Integrate with Gastrulation
Describe the embryology behind sacrococcygeal
Gynaecology
Describe the Prenatal and postnatal maturation of Gametogenesis teratoma and justify its clinical picture.
Integrate with
F-A-012 Oogenesis
oocyte Gynecology Describe the molecular factors responsible for
Describe the significance of arrested development of Gametogenesis gastrulation.
F-A-013 Oogenesis
oocyte Describe the Invagination and movement of
Embryology
Compare and contrast oogenesis and prenotochordal cells
F-A-014 Gametogenesis Describe the Notochordal plate formation Describe
spermatogenesis
Describe the hormonal control of female reproductive the Neuroenteric canal formation

cycles Describe the fate of the notochord

Enumerate and describe the steps of the ovarian Describe the Establishment of body axis

cycle Draw and label the fate map establishment Formation of

F-A-024 Embryology
Describe the process of ovulation Female Describe the Fate map establishment notochord
Integrate with
F-A-015 Reproductive
Describe the formation, function and fate of corpus Gynecology Describe the molecular basis for notochord formation
Cycle
luteum Describe the role of notochord as an inducer
Define Mittelschmerz pain Describe the embryological basis for situs inversus,
Define menstrual cycle Sirenomelia, holoprosencephaly
Describe the phases of menstrual cycle Describe the development of trophoblast and
Transportation of chorionic villi during 3rd week of development
F-A-016 Describe the transportation of Oocyte
gametes Describe the Formation of neural tube from neural
Describe Capacitation & Acrosomal Reaction Embryology
plate. Derivatives of
F-A-017 Fertilization F-A-025 Embryology
Define fertilization ectoderm
Justify embryologically the clinical picture seen in
94 96

Describe the phases of fertilization Draw and label a various neural tube defects
diagram illustrating the phases of fertilization Describe the process of Migration of neural crest
Enumerate and describe the results of fertilization cells
Define contraception Enlist the Derivatives of neural tube and describe the
Explain the mechanisms of following contraceptive fate of each
techniques: Enlist the Derivatives of neural crest cells
1. Barrier methods Integrate with Contraception Enlist the ectodermal derivatives
F-A-018
2. Hormonal methods physiology Describe the molecular and genetic factors for the
3. Intrauterine device (IUD) process of neurulation
4. Emergency contraceptive pills (ECPs) Describe important Neural tube defects
5. Male and female sterilization Describe the Differentiation of mesoderm into its
Describe the anatomical and physiological basis of constituting components
male and female infertility Describe the Somite formation and its fate Describe Integrate with Mesodermal
F-A-026
pediatrics derivatives
Define assisted reproductive techniques Describe the Infertility & the Estimation of age by somites Describe the
Integrate with
mechanisms of In vitro fertilization (IVF) & embryo assisted
F-A-019 Gynecology formation of intra-embryonic coelom
reproductive
transfer techniques Describe the processes of vasculogenesis &
Explain the correlation of multiple births with assisted angiogenesis
reproductive techniques Explain the features of primordial cardiovascular Early
Integrate with
Describe the process of cleavage of embryo and F-A-027 development of
system Cardiology
CVS
blastocyst formation Describe the anatomical justification for
Describe the origin and uses of embryonic stem cells Capillary hemangiomas
and the techniques of obtaining these cells from the Embryology Describe the Cephalo-caudal folding Integrate with Folding of
embryo (reproductive cloning & therapeutic cloning) F-A-028
Describe the Lateral folding Gynaecology embryo
Cleavage,
Explain the embryological basis of spontaneous Enlist the derivatives of germ layers
F-A-020 blastocyst
abortion. formation Enlist and Describe the Derivatives of intermediate
Integrate with Embryology
Compare and contrast the villi. and lateral plate mesoderm Enlist & Describe the
Gynaecology Germ layer
F-A-029
Derivatives of endoderm derivatives
Describe the process of Compaction.
Integrate with
Describe the Formation of morula (division into Embryology Enlist & describe the derivatives of ectoderm Gynaecology/
inner and outer cell mass) Pediatrics
Describe the Uterus at the time of implantation Describe the Regulation of embryonic development Control of the
Implantation F-A-030 embryonic
F-A-021 (decidua reaction) Embryology Week 2 of by HomeoBox genes development
Embryology
Illustrate the concept of Implantation. Development Folding of
F-A-031 Enlist the characteristic features of the embryo during
Embryo

95 97
 2nd month Embryonic Describe stem cell transplantation and gene therapy
period
Describe the criteria for estimating the developmental Molecular
Define morphogens, protein kinases, notch delta regulations and
staging in human embryos Explain the estimation of F-A-038
pathway, transcription factors, epigenetics signaling
gestational & embryonic age pathways
Explain the measurement and Define teratology and causes of birth defects
characteristics of fetus/Key events during Embryonic Define genomic imprinting
Period. Define human disorders associated with genetic
Describe the Overview of External appearance of mutations
fetus during fetal period. Enlist developmental Describe birth defects caused by genetic factors:
horizons during fetal life event. numerical and structural anomalies
F-A-032 Fetal Period
Describe Viability of fetuses and low birth weight Define and enlist the teratogens
babies Describe the role of following in causing teratogenicity
Explain the factors influencing fetal growth in humans:
F-A-039 Teratogenicity
Describe the clinical problems 1. Drugs
encountered by babies born with IUGR (Intra Uterine 2. Environmental agents
Growth Restriction) 3. Chemicals & heavy metals
Tabulate the criteria for estimating fertilization age 4. Infectious agents
during the fetal period 5. Radiation
Describe the procedures for assessing fetal status 6. Hormones
Integrate with
F-A-033 Fetal Status
Describe the clinical picture of IUGR & factors Gynaecology 7. Maternal diseases
resulting in IUGR (Intra Uterine Growth Restriction) Describe the basis for male-mediated teratogens
Define Pre-eclampsia Describe prevention of birth defects
List the fetal membranes MICROSCOPIC ANATOMY (HISTOLOGY AND TOTAL HOURS = 08
PATHOLOGY)
Describe the macroscopic & microscopic features of CODE
Decidua SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Enlist the various parts of decidua Functionally Introduction to
Describe different types of microscopies Describe Basic technique microscopy &
correlate the parts of the decidua with its structure F-A-040
Staining methods and their significance in Histology Basic staining
Describe the Changes in the trophoblast leading to Integrate with
F-A-034 Placenta technique
Gynaecology
the development of placenta Describe the Structure Describe the electron microscopic structure and fluid
(macroscopic & microscopic) of placenta mosaic model of plasma membrane
F-A-041
Enlist & correlate the Functions of placenta with its Draw the fluid mosaic model of plasma membrane Basic Histology Cell membrane
structure Describe the structure of glycocalyx coat and lipid raft
Describe the Microscopic anatomy of Placental and correlate it with function

98 100

membrane Describe different types of membrane

Describe the Placental circulation (fetal & maternal) proteins and their functions
Embryologically justify the hemolytic disease of the Explain different modes of transport across the cell
neonate (Erythroblastosis fetalis) membrane
Describe the functions of placenta List the membranous and non-
Describe the Formation & fate of Umbilical cord membranous cellular organelles
Describe the Cord abnormalities Describe the structure of the following cellular
Justify embryologically the clinical features observed organelles and correlate with their function:
in Absence of umbilical artery 1. Ribosomes
Describe the formation and circulation of 2. Endoplasmic reticulum (rough & smooth)
Integrate with
Amniotic fluid 3. Golgi apparatus Pathology
Describe the Procedure of diagnostic amniocentesis Integrate with Fetal 4. Lysosomes
F-A-035
Explain the significance of amniotic fluid Gynecology membranes 5. Proteasomes
Describe the factors responsible for Polyhydramnios F-A-042 6. Mitochondria Cell organelles
and oligohydramnios 7. Peroxisomes
Describe the consequences of oligohydramnios and Describe the structural components of cytoskeleton,
polyhydramnios Define Amniotic Bands and correlate them with their functions
Explain the formation and fate of umbilical vesicle Explain the histological basis of immotile cilia
(yolk sac) Define Physiological Umbilical Hernia syndrome
Describe the development of Dizygotic twins Describe the histological features of cytoplasmic Integrate with
Describe the development of Monozygotic twins inclusions Pathology
Describe the fetal membranes in twin pregnancy Describe the structure of nuclear envelope and Integrate with
Describe Fetus Papyraceous Multiple
F-A-036 nuclear pores Physiology
pregnancies
Explain the zygosity of the twins Describe the structure of chromatin
Describe the characteristics of various types of Describe the structure of chromosome
conjoined monozygotic twins Describe the structure of nucleolus
Embryology
Define preterm Birth Describe the structure and types of DNA (Deoxy Histology
Describe parturition & three stages of Labor. Ribonucleic Acid) and RNA (Ribonucleic Acid)
Describe the Various methods of prenatal diagnosis F-A-043 Cell nucleus
Describe the histological basis for apoptosis and
Prenatal
F-A-037 Describe the Fetal therapy diagnosis and necrosis
Describe Maternal serum Screening fetal therapy
Describe structure of different types of cell junctions
Corelate levels of Alpha feto protein levels and fetal Integrate with
Describe the cell cycle & cell division
Pathology
anomalies Define important clinicopathological terms:
99 101
 Atresia, Hypertrophy, Atrophy, Hyperplasia, EMBRYOLOGY TOTAL HOURS = 05
Metaplasia, Anaplasia, Neoplasia, Inflammation, CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Metastasis
Calculate fertilization age, gestational age,
Describe the histological structure and function of
embryonic/fetal age and expected date of delivery.
basement membrane (light and electron)
On models, charts, aborted embryos and fetal
Draw and label a diagram illustrating the electron
specimens, identify the:
microscopic structure of basement membrane
Events of embryonic period, i.e., cleavage, morula
Describe the basal surface modifications of epithelia
Histology and blastula formation, yolk sac, amniotic cavity,
Describe the electron microscopic structure and
connecting stalk,
functions of intercellular junctions (lateral surface
Gastrulation (notochord & primitive streak, three germ
modifications) and give their locations
layers and their parts/derivatives), angiogenesis,
Describe the Biochemical composition of the
neurulation, somites and embryonic age
basolateral modifications
determination based on it, chorionic villi (primary,
Describe the electron microscopic structure &
secondary & tertiary), developmental defects
functions of the following apical cell surface
(sacrococcygeal teratoma, neural tube defects)
F-A-044 specializations: Integrate with Epithelium
Placenta and it’s positional & Implatational variations,
1. Microvilli Biochemistry
umbilical cord and its contents
2. Stereocilia Anatomy Embryology
F-A-047 Fetal features during fetal period. Determine age of
3. Cilia
fetus based on these features.
Classify and exemplify the epithelia with their Integrate with
Describe the USG (Ultrasonography) report for the:
histological structure, locations and functions Pathology
Fetal features, fetal age estimation, placental
Describe the structure of exocrine glands Explain the
attachment with variations, fetal membranes and
mechanism of transport across the epithelia
multiple pregnancies
Describe the classification of exocrine glands on the
Gastrulation (notochord & primitive streak, three germ
basis of: Histology
layers and their parts/derivatives), angiogenesis,
1. Shape of secretory portions and ducts
neurulation, somites and embryonic age
2. Mode of secretion
determination based on it, chorionic villi (primary,
3. Type of secretion
secondary & tertiary), developmental defects
Describe the composition and list the constituents of
(sacrococcygeal teratoma, neural tube defects) fetal
connective tissue Classify the connective tissue with
Connective features during fetal period. Determine age of fetus
F-A-045 examples Histology
tissue based on these features.
Describe the composition of ground substance of
Describe the USG (Ultrasonography) report for the:
connective tissue

102 104

Describe the composition, distribution, and function of Fetal features, fetal age estimation, placental
glycosaminoglycans in connective tissue attachment with variations, fetal membranes and
Describe connective tissue fibers, cells. Define multiple pregnancies
Fibrosis HISTOLOGY TOTAL HOURS = 14
Describe the structure, distribution, and functions of CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
the cells of macrophage mononuclear phagocytic
Describe different types of staining techniques and
system
their significance with special emphasis on H&E Staining
F-A-048
Describe the role of macrophages in innate immunity techniques
Integrate with (Hematoxylin and Eosin) staining
& formation of foreign body Giant cell Biochemistry/
Physiology Enlist important features of different parts of light
Describe the structure & functions of Mast cells. Role F-A-049 Microscope
microscope
of Mast cells in immediate hypersensitivity reactions.
Identify and draw & label different cell shapes under
Describe structure of Plasma cells and their role in F-A-050 Cell shape
the microscope
antibody formation.
Identify under light microscope and Draw & Label the
Describe the types of adipose tissue (white & brown),
Histology following types of epithelia:
their histogenesis, locations and function
Microscopic
1. Simple squamous
Describe lipid storage and mobilization in and from Anatomy
Integrate with 2. Simple cuboidal
adipocytes and compare the brown and white adipose
Pathology 3. Simple columnar (ciliated & non-ciliated)
tissue
4. Pseudostratified columnar (ciliated & non-
F-A-051 Epithelium
ciliated)
5. Stratified squamous (keratinized & non
ANATOMY TOTAL HOURS = 03 keratinized)
CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC 6. Stratified cuboidal
7. Stratified columnar
Demonstrate the anatomical terms of position and
8. Transitional
movement, in particular on limbs.
Identify under light microscope and Draw & Label

Demonstrate various anatomical movements of body F-A-052 serous & mucous secreting glands under light Epithelium
Osteology Microscopic
Identify various elevations and anatomical landmarks microscope
Imaging and Anatomy
F-A-046 on bones. Anatomy cross-sectional Identify under light microscope and Draw & Label the Connective
Anatomy F-A-053
various types of connective tissue tissue
Identify and interpret normal radiographs of various Arthrology
body regions
Identify and interpret joint dislocations and displaced
fracture bone segments radiographically.

103 105
 Enlist the abnormal types of hemoglobin
NORMAL FUNCTION
Enumerate the types of white blood cells
THEORY
Describe the characteristics and functions of
MEDICAL PHYSIOLOGY TOTAL HOURS = 40
Neutrophils
CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC Explain the process of defense against invading

Define Homeostasis agent by neutrophils

Explain control system of body by giving examples Define leukocytosis and leukopenia

Differentiate between Extracellular and Explain the effects of leukemia on body

Intracellular Fluids Explain the process of defense against invading

Explain the positive and negative feedback agent by macrophages

mechanisms with examples Discuss different lines of defense during inflammation Medical White Blood
F-P-005
Physiology Cells
Explain the significance of feed forward/ adaptive Explain the functions of neutrophils and macrophages
control/delayed negative feedback mechanisms in spread of inflammation (walling off effect)
Explain the structure of cell membrane Define the Reticuloendothelial system
Enlist the types of cell membrane proteins Enlist the different components of
Enumerate the functions of membrane proteins Reticuloendothelial system
Define and enumerate the functions of cell Glycocalyx Explain the characteristics and functions of basophils
Enlist membranous and non-membranous organelles Explain the characteristics and functions of
Enlist the self-replicative organelles Medical
F-P-001 Cell Biology eosinophils and enlist conditions in which these cells
Physiology
Differentiate between the functions of smooth and are raised.
rough endoplasmic reticulum
Enumerate different blood group types.
Explain the functions of Golgi apparatus
Explain the basis of ABO and Rh blood system Medical
F-P-006 Blood Types
Enlist the enzymes of lysosomes Physiology
Explain the Landsteiner law
Explain the functions of lysosomes
Enlist the enzymes of peroxisomes Discuss Components of ANS (Autonomic nervous

Explain the functions of peroxisomes system)

Enumerate the components and functions of Explain the physiological anatomy of sympathetic Medical
cytoskeleton and parasympathetic nervous system Physiology
Autonomic
F-P-007 Also integrate
Define and enlist types of endocytosis Describe the types of adrenergic and nervous system
with Anatomy
Explain the mechanism of pinocytosis cholinergic receptors and their functions part of ANS

Classify different transport mechanisms Explain the effects of sympathetic and

Compare the composition of Na (Sodium), K parasympathetic on various organs/ system of body

106 108

(Potassium) and Cl (Chloride) in extracellular and

intracellular fluid
Define and enlist different types of diffusion Explain
PHYSIOLOGY TOTAL HOURS = 12
the process of facilitated diffusion with the aid of CODE
diagram SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC

Define and classify different types of active transport Explain laboratory/clinical procedure to the subject.
Describe primary and secondary active transport with F-P-008 Obtain verbal consent from subject before starting a Consent
examples procedure. Reassure the subject after the procedure.
Explain voltage and ligand gated channels with Determine Erythrocyte Sedimentation Rate and RBCs (Red
F-P-009
examples packed cell volume Blood Cells)

Name Na, K channel Blockers. F-P-010 Determination of blood group Medical Blood Group
Discuss functions and significance of Na/K ATPase Interpret Total Leucocyte Count, Differential Physiology

pump. Leucocyte Count (normal & abnormal) in a CBC

Enumerate the functions of blood (Complete Blood Count) report generated by WBCs (White
F-P-011
Explain the composition of blood Automated Cell Counter Blood Cells)

F-P-002 Enumerate the plasma proteins Blood Identify various types of WBCs in a prepared DLC
Discuss functions of plasma proteins (Differential Leukocyte Count)
Describe the pathophysiology of edema THEORY
Discuss the characteristics of red blood cells
MEDICAL BIOCHEMISTRY TOTAL HOURS = 36
Explain different types of Bone marrows Enumerate Medical
CODE
Physiology
the different sites of erythropoiesis at different ages SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Explain the stages of erythropoiesis Differentiate between different types of cells.
Enumerate factors that regulate erythropoiesis Red Blood
F-P-003 Explain the concept of organization of cells to tissue,
Cells
Discuss the site and role of erythropoietin in red F-B-001 tissues to organ, organs to system. Structure of cell
blood cell production Differentiate between the eukaryotic and prokaryotic
Explain the significance of vitamin B12 and folic acid cells.
in maturation of red blood cell Describe the composition and structure of cell on Biochemistry
Enumerate the types of normal hemoglobin in biochemical basis and justify it as fluid mosaic model. Cell Biology
different ages of life Describe the structure and function of cell membrane
Explain the role of Iron in Hemoglobin formation. with particular reference to the role of Cell
Medical F-B-002
F-P-004 Hemoglobin Membrane
Define blood indices, give their normal values & Physiology 1. Lipids
enumerate the conditions in which these values are 2. Carbohydrates
disturbed 3. Proteins

107 109
 Explain why the cell membrane is called fluid mosaic 3. uncompetitive
model
Discuss the various ways of cell- Explain the application of enzyme in clinical diagnosis
to-cell communication and to the environment. and therapeutic use
Describe cell to cell communications. Cell signaling Signal
F-B-003
pathways (only G protein signaling I e. Gs, Gi and transduction
Classify amino acids based on polarity, nutritional
Gq) importance and glucogenic/Ketogenic properties
Describe cell to cell adhesion. F-B-011 Amino acids
Explain the biochemical markers and importance of Explain the structure, physical, chemical properties of
subcellular organelles and their inherited disorders amino acids and their biomedical importance
especially:
Subcellular
F-B-004 1. cell disease Classify proteins on the basis of functions, solubility
organelles
2. Refsum disease and physicochemical properties
3. Parkinsonism 1. Explain its biomedical importance
4. Progeria
2. Distinguish between class A and B proteins
Describe the chemistry of purines and pyrimidines
Chemistry of
F-B-005 and their linkage in nucleic acid synthesis and their purine and Explain the structural levels of proteins
metabolism pyrimidines
1. Differentiate between alpha helix and beta
Discuss the organization of DNA with special F-B-12 pleated protein structures Protein
reference to Watson and crick model, composition, DNA (Deoxy 2. Identify bonding at different levels of proteins
F-B-006 Ribonucleic
structure, role of Pairing
Acid)
Describe the structural forms of DNA Describe the role of chaperons in protein folding
Discuss the structure of different types of RNAs with 1. Interpret disorders related to protein misfolding
special reference to composition, linkage, functions of on basis of given data
2. Describe the biochemical basis of Alzheimer’s Biochemistry
RNA, micro-RNA
RNA Cell Biology
Illustrate the structure and functions of various types Biochemistry disease/ prion disease
F-B-007 (Ribonucleic
Cell Biology
of RNAs Acid)
Classify and explain the bio-chemical role of each
Describe the functions of various small RNAs present F-B-13 Plasma proteins
class of plasma proteins
in cell
Explain the structure and nomenclature of
nucleotides, biomedical importance of natural and Biochemistry
F-B-008 Nucleotides
synthetic analogues Cell Biology
Interpret the role of synthetic analogues of

110 112

nucleotides in medicine based on sign/symptoms and Explain the structure and biochemical role of
data e.g Methotrexate, 5 Flurouracil and Allupurinol. immunoglobulins
Explain the higher organization of DNA. Difference 1. Describe the production, structure and
F-B-009 Chromosome
between DNA, chromatid and chromosome functions of B cells, plasma cells, and
Describe enzymes with reference to: antibodies (IgA, IgD, IgE, IgG, and IgM).
1. Active sites 2. Discuss the functions of the cytokines
F-B-14 Immunoglobulins
2. Specificity (Interleukins (ILs), Tumor Necrosis Factor
3. Catalytic efficiency (TNFs), IFs, Platelet derived growth factor
4. Cofactor (PDGF), and Platelet activating factor (PAF)).
5. Coenzyme 3. Interpret multiple myeloma on basis of given
6. Holoenzyme data
7. Apoenzyme
8. Prosthetic group
9. Zymogens
10. Location
BIOCHEMISTRY TOTAL HOURS = 09
Classify enzymes according to the reaction they CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
catalyze and their nomenclature
Demonstrate the step taken to prevent or rectify the
F-B-015 Lab hazards
F-B-010 Explain the mechanism of enzyme action from Enzymes Laboratory Hazards
reactants to products (catalysis). F-B-016 Identify the structure of cells under microscope cell

Discuss the effect of various factors on enzymatic F-B-017 Identify the methods of isolation of cell organelles’ Cell organelles

activity: Identify the different parts of equipment i.e.,

centrifuge, Microlab, Electrophoresis, Hot Oven, Biochemistry
1. Substrate concentration F-B-018 Equipment

2. Temperature water bath

3. PH Detection of amino acids by paper chromatography

4. Enzyme concentration Chromatography
F-B-019 Prepare different types of solution Molar, Molal, Solutions
Explain the regulation of enzymatic activity (Michaelis Normal and %
Menten and Line weaver Burk’s equation). THEORY
Discuss inhibitors of enzymatic activity Biochemistry
PATHOLOGY TOTAL HOURS = 12
(with special reference to Km/V max) Cell Biology
CODE
1. Competitive SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
2. Non competitive General
F-Pa-001 Discuss the significance of pathology. Cell Injury
Pathology
111 113
 Discuss the causes of cell injury. Explain Germ theory & multifactorial causation Health
Identify the types of cell injury. Describe the Describe Epidemiological Triad
mechanism of cell injury.
Discuss Web of disease causation
Identify the types of cell death.
Define necrosis and apoptosis. Describe Gradient of infection

Describe different types of necrosis.

Describe principles of prevention and control on
Compare apoptosis with necrosis.
prevalent diseases
Identify different types and mechanism of cellular
Explain difference between elimination and Community
adaptations to stress Medicine Disease
F-CM-005 eradication
Discuss the mechanism and types of intracellular and Public Prevention
Describe disease surveillance, types and cycle
Health
accumulations and pathological calcifications
Explain Primary, secondary, & tertiary prevention
Enumerate the microbes causing infectious diseases.
Describe five levels of interventions
Describe the structure of bacterial cell
Differentiate cell walls of gram positive and gram-
IMPACT (EPIDEMIOLOGY, SOCIOLOGY/SOCIETY, COMMUNITY MEDICINE & PUBLIC HEALTH)
negative bacteria.
Compare the structure of bacterial cell and virus THEORY

F-Pa-002 Discuss the growth curve of bacteria. Introduction to TOTAL HOURS = 08

Microorganisms CODE SPECIFIC LEARNING OBJECTIVES
Enlist steps of viral replication DISCIPLINE TOPIC
Identify types of bacterial infections Identify the Biological Basis of human behavior and
Enlist stages of bacterial pathogenesis General
discuss social behavior
Microbiology
Discuss the determinants of bacterial F-BhS- Describe processes such as neurobiology of memory, Biological Basis
001 of Behavior
pathogenesis emotions, sleep, learning, motivation, sex, arousal,
Define sterilization and disinfection. reward and punishment
Describe the principles of sterilization and Identify the burden of mental illness on the person,
disinfection. family and society
Sterilization & F-BhS- Psychological
F-Pa-003 Behavioral
Describe clinical uses of common disinfectants and Disinfection 002 Describe Intellectual disability, Mental Disorders and Disorders
Sciences
their mode of sterilization Personality Disorders
Discuss physical and chemical agents of sterilization Identify the role of psychosocial factors in various
illnesses
PHARMACOLOGY AND THERAPEUTICS
F-BhS- Describe psychosocial aspects of various system
Psychology and
THEORY 003 diseases such as Cardio-vascular system (CVS), Disease

TOTAL HOURS = 04 Central Nervous System (CNS), Gastro Intestinal

CODE SPECIFIC LEARNING OBJECTIVES
DISCIPLINE TOPIC Tract (GIT), Respiration, renal, endocrine and Cancer

114 116

Definitions of Pharmacology, drug, pro-drug, placebo, Identify the behavioral factors associated with
Absorption,
active principles, sources of drugs; General Distribution, pharmacological treatment of diseases Behavioral
F-Ph-001 Metabolism and F-BhS-
Brief outline of Absorption, Distribution, Metabolism Pharmacology Discuss Health belief model, treatment compliance Factors &
Excretion of 004 Pharmacological
and Excretion drugs and its psychosocial factors, social factors in drugs Treatment
Definitions of receptor, agonist, partial agonist, prescription and drug resistance
inverse agonist, antagonist and types of receptors Identify the rehabilitation work for patients on dialysis
Basic
F-Ph-002 and second messengers; terminologies of and any kind of physical disability
Diagrammatic concept of signaling Pharmacology F-BhS- Discuss the care requirements in chronic debilitating Palliative Care
005
mechanisms General conditions like Diabetes, Multi-infarcts Dementia,
Pharmacology
Pharmacological aspects of Autonomic chronic renal disease, limb amputation
Behavioral
Receptors Identify the various physiological effects of stress Sciences
Autonomic
F-Ph-003
(types of autonomic receptors, important sites and System Explain ANS response to stress,
actions) F-BhS-
Describe Behavioural manifestations of stress, Stress Stress
006
COMMUNITY MEDICINE & PUBLIC HEALTH related multiple sclerosis and autoimmune
diseases
THEORY
AGING
TOTAL HOURS = 08
CODE SPECIFIC LEARNING OBJECTIVES
DISCIPLINE TOPIC THEORY
Describe the changing concepts and new philosophy TOTAL HOURS = 01
Concept of CODE SPECIFIC LEARNING OBJECTIVES
F-CM-001 of health DISCIPLINE TOPIC
Health
Explain responsibility for health Geriatrics
F-Ag- Discuss telomeres and telomerase and their clinical
Explain dimensions and determinants of health and Integrate with Process of Aging
001 significance in aging.
Biochemistry
their role in achieving positive health Positive Health
Dimensions,
F-CM-002 Discuss concept of health and wellbeing Community
Medicine Health
Describe the Physical quality of Life Index & Human Determinants
and Public
Development Index Health
Describe the importance of health indicators
Classify health indicators
F-CM-003 Calculate Morbidity and Mortality Health indicators
Describe Disability indicators
Compare indicators among countries
Conceptualize disease causation and natural history Community
Disease
F-CM-004 Medicine
of disease causation
and Public
115 117
 Enlist and explain the conditions that cause excessive
NORMAL STRUCTURE
bleeding
THEORY HL-P-006 Define thrombocytopenia Coagulation
disorders
Enlist the causes and consequences of Integrated with
GROSS ANATOMY TOTAL HOURS = 02 Medicine
CODE Thrombocytopenia
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC
Define immunity
Identify and describe the components of the Classify immunity
Hematopoietic & Lymphoid Tissue and their function
Explain humoral immunity
Location, coverings, relations of Spleen Explain Innate immunity.
Origin, course branches and distribution of Elaborate cell mediated immunity.
Splenic artery Hematopoietic &
HL-A-001 Human Describe the structure of antigen and immunoglobulin
Lymphoid
Anatomy Describe the role of Helper T-cells in cell mediated Medical
Venous drainage of Spleen, Portal vein formation, Tissue HL-P-007 Immunity
immunity Physiology
tributaries, and area of drainage.
Enlist the types of Immunoglobulins along with their
Location and relations of Thymus. Age related functions
changes in Thymus Explain the role of memory cells in enhancing
antibody response (secondary response)
EMBRYOLOGY & POST-NATAL
TOTAL HOURS = 01
DEVELOPMENT Describe the mechanism of action of antibodies
CODE
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC Elaborate the complement system.
Developmental Elaborate Immune tolerance
HL-A-002 Intrauterine Development of spleen Embryology Anatomy of Explain the process of clone selection during T cell Medical
Spleen HL-P-008 Tolerance
processing Physiology

Discuss the failure of tolerance mechanism

Discuss immunization. Immunization
HISTOLOGY TOTAL HOURS = 02
CODE Define passive Immunity
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC Explain features and physiological basis of delayed
Medical
Light microscopic structure of Spleen, thymus, Histological
reaction allergy. Physiology
HL-P-009
HL-A-003 Lymph features of Explain features and physiological basis of Atopic Integrate with Immunization
nodes, tonsils and Mucosa Associated Histology Pediatrics
lymph node,
Lymphoid Tissue (MALT) including appendix. Allergy
spleen & thymus
Explain features and physiological basis of
Anaphylaxis, urticaria and Hay fever.

124 126

Discuss the pathophysiology, features and treatment

NORMAL FUNCTION Medical Blood group
HL-P-010 of ABO and RH incompatibility.
Physiology Incompatibility
THEORY Enlist the changes that take place in the stored Blood.
Discuss the features and complications of
MEDICAL PHYSIOLOGY TOTAL HOURS = 20
CODE mismatched blood transfusion reaction Blood mismatch
HL-P-011 Integrate with
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC Describe the Hazards of blood transfusion. Transfusion
Pathology
reactions
Define, classify and explain anemia on the basis of
Elaborate the Transplantation of Tissues and Organs
HL-P-001 morphology and cause Anemia
Explain the process of tissue typing Medical
Discuss the effects of anemia on the body
Physiology Transplantation
HL-P-012 Explain the prevention of Graft Rejection by
Define polycythemia Integrate with of tissues
HL-P-002 Polycythemia suppressing immune system Nephrology
Explain types of polycythemias
Discuss the effects of polycythemia on the body THEORY
Define hemostasis
MEDICAL BIOCHEMISTRY TOTAL HOURS = 19
HL-P-003 Describe the mechanisms by which hemostasis is Hemostasis CODE
secured SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Explain the steps of synthesis of hemoglobin and
Discuss the characteristics and functions of platelets
HL-P-004 Platelets interpret Porphyrias on basis of sign symptoms and

Explain the mechanism of formation of platelet plug data.

Medical Discuss the biochemical role and types of hemoglobin
Enlist the clotting factors in blood Physiology
1. Differentiate Hemoglobin and myoglobin
Explain the conversion of Prothrombin to Thrombin &
HL-B-001 2. Explain oxygen dissociation curve of hemoglobin Medical Hemoglobin and
formation of Fibrin Fibers Biochemistry its types/ RBCs
and myoglobin and factors regulating them
Explain the Intrinsic & extrinsic clotting pathway.
3. Interpret Carbon monoxide (CO) toxicity on the
Name & explain the mechanism of anticoagulants
basis of sign and symptoms
used in laboratory.
4. Explain the role of 2,3 Bisphosphoglycerate (2,3
HL-P-005 Explain the factors that prevent intravascular Coagulation
factors BPG) in fetal circulation
coagulation
Discuss haemoglobinopathies and their biochemical
Explain the role of Calcium ions in Intrinsic and
and genetic basis with special emphasis on sickle cell
Extrinsic pathways
anemia, Thalassemia and methemoglobinemia Medical Hemoglobino
Enlist the vitamin K dependent clotting factors HL-B-002 Biochemistry pathies/
a) Discuss the following types of anemia on the basis
Integrate with RBCs/
Explain the prothrombin time, International of signs and symptoms and laboratory data: Pathology Homeostasis
Normalized Ratio (INR), and its clinical significance. 1. Hypochromic microcytic
2. Normochromic microcytic
125 127
 3. Normochromic normocytic PATHOPHYSIOLOGY AND PHARMACOTHERAPEUTICS
4. Macrocytic (megaloblastic)
THEORY
Explain the iron metabolism with mechanism of
absorption and factors affecting it. TOTAL HOURS = 2+5=07
CODE SPECIFIC LEARNING OBJECTIVES
1. Interpret Iron deficiency anemia on basis of given DISCIPLINE TOPIC
Medical
data and microscopic findings Iron
HL-B-003 Biochemistry Describe the oral and parenteral iron preparations
Metabolism/
2. Interpret folic acid and cobalamin in relation to Integrate with including their pharmacokinetics, uses, adverse
RBCs Pharmacology
medicine
anemias on given data and microscopic findings HL-Ph-001 effects & Anemia
3. Discuss biochemical role of pyridoxine and vitamin Therapeutics
Vitamin B12 preparations, Iron Antidotes
C in microcytic anemia
Discuss the degradation of heme in macrophages of Should know the terms: Hematopoietic growth
reticuloendothelial system factors, their name, mechanism of actions, uses and
Heme
HL-B-004 1. Describe the formation of bile pigments, their Degradation/ adverse effects
types and transport RBCs
Define and classify anemias according to underlying
2. Discuss the fate of bilirubin
mechanism and Mean Corpuscular Volume/ Mean
Discuss hyperbilirubinemias and their biochemical Corpuscular Hemoglobin (MCV/MCH)
basis Discuss the causes and investigations of iron
Medical Hyperbilirubi
1. Differentiate types of jaundice on basis of Biochemistry nemias / deficiency anemia and megaloblastic anemia
HL-B-005 Blood
sign/symptoms and data RBCs/ Blood
Groups Classify the benign and malignant disorders of WBCs Cells,
2. Evaluate the genetic basis of jaundice on the HL-Pa-001 Pathology Platelets and
basis of lab investigations Blood
Discuss the causes leading to reactive leukocytosis Group

Classify and explain the biomedical importance of Plasma Interpretation of anemias on the basis of peripheral
HL-B-006 Proteins/
each class of plasma proteins blood smear and bone marrow findings
Homeostasis

Classify bleeding disorders

Discuss first line laboratory investigations for

bleeding disorders

Describe the basic concept of blood grouping and

acute hemolytic transfusion reaction

128 130

Explain the structure and biochemical role of DISEASE PREVENTION AND IMPACT
immunoglobulins
THEORY
1. Describe the production, structure and
functions of B cells, plasma cells, and antibodies Immunoglob TOTAL HOURS = 05
HL-B-007 ulins/ WBCs/ CODE SPECIFIC LEARNING OBJECTIVES
(IgA, IgD, IgE, IgG, and IgM). DISCIPLINE TOPIC
Immunity
2. Discuss the functions of the cytokines (ILs, TNFs, Describe the nutritional aspects of iron deficiency
HL-CM-01 Anemia
IFs, PDGF, and PAF). anemia and psychological aspects of diseases
Interpret multiple myeloma on basis of given data Enlist most common blood borne diseases in Community
Pakistan Medicine and
communicable
HL-CM-02 Public Health
Explain and interpret pedigree of single gene defect Describe the routes of spread of blood borne diseases
HL-B-008 i.e. sickle cell anemia (Autosomal recessive) and Genetics diseases
Beta Thalassemia (X linked recessive) HL-CM-03 Genetic diseases
Genetic counseling of parents
Psychological Counselling of patients and their Counselling,
HL-BhS-01 informational
families
care

TOTAL HOURS = 6+6=12 Identify and deal with the various psychosocial Behavioral
CODE SPECIFIC LEARNING OBJECTIVES
aspects of Hematopoietic System disorders (such as Sciences Personal,
DISCIPLINE TOPIC HL-BhS-02 Psychosocial and
Interpret the Red Blood Cell Count, Hemoglobin Sickle Cell Disease, Hemophilia, and Conditions of
vocational issues
concentration, Hematocrit and RBC Indices by the Blood) on Individual, Family and Society.

Automated Cell Counter Bleeding/

HL-P-013 AGING
Interpret the Total Leucocyte Count Clotting time
Medical
Differential Leucocyte Count THEORY
Physiology
Platelet Count by Automated Cell Counter. TOTAL HOURS = 01
Jaundice & CODE SPECIFIC LEARNING OBJECTIVES
Determine Bleeding Time. Anemias/ DISCIPLINE TOPIC
HL-P-014
Determine Clotting Time. RBCs/
Discuss the role of platelets in Platelet-Rich Plasma Platelet Rich
Homeostasis
HL-Ag-01 Plasma
Jaundice & (PRP) treatment in old age (for skin, hairs and joints)
Interpret types of jaundice on the basis of data Biochemistry Therapy
HL-B-009 Medical Anemias/
/Dermatology
Perform estimation of bilirubin Biochemistry RBCs/
Homeostasis HL-Ag-02 Explain the role of glutathione in skin whitening Glutathione

129 131
 NORMAL STRUCTURE contents
Describe Axillary Artery with reference to its 3 parts
THEORY
their relations, branches, and anastomoses
GROSS ANATOMY TOTAL HOURS = 105
Describe the formation, tributaries, and drainage of
CODE
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC Axillary Vein
UPPER LIMB Identify and demonstrate the course/ relation and
Describe the topographical anatomy of Pectoral branches/tributaries of axillary vessels
Region Describe the Axillary Lymph Nodes in terms of
location, grouping, areas of drainage and clinical Human
Perform dissection of the Pectoral Region or use Human Pectoral
MS-A-001 Anatomy
models to identify the key structures Anatomy Region significance
Describe muscles of the Pectoral Region with their Describe the course, relations, root value and
origin, insertion, nerve supply and actions. distribution of Axillary nerve.
Describe the cutaneous nerves. and Superficial Describe the boundaries and contents of
Human
Dermatomes
veins of the Upper Limb. Anatomy quadrangular space.
MS-A-002 and cutaneious
Describe the extent, attachments, and structures innervation of Describe the Osteology of Humerus (Side
Human
Upper Limb MS-A-007 Determination, morphological features, attachments, Bones of upper
passing through Clavipectoral Fascia Anatomy
limb: Humerus
Describe the extent, structure, vascular supply, ossification)
Human
lymphatic drainage of Breast (Mammary Glands) Anatomy Describe the Shoulder Joint under the following
Define the boundaries of auscultation and state headings: Articulation, Type/ Variety, Capsule,
Integrate with
its clinical significance Medicine Ligaments, Innervation, Blood supply, Movements.

Demonstrate palpation of breast and define its Describe the 3 parts of Deltoid Muscle and correlate
Integrate with
relation to the Fibrous septa in Carcinoma of Breast Surgery them with its unique functions.
Explain its role in abduction of shoulder joint. Human
Explain the anatomical basis of position adopted for Pectoral region
Integrate with Anatomy
& Explain mechanism of Abduction of arm Joints of Upper
breast examination and mammography. Radiology
MS-A-003 Back MS-A-008 Limb: Shoulder
Describe the osteology of the bones in pectoral + Identify and demonstrate the movements of scapula
Joint
region. Mammary and shoulder joint.
Glands
Enumerate the superficial muscles of back, Draw and label the arterial anastomosis around

connecting shoulder girdle with vertebral column. shoulder joint

Human
Anatomy Describe, in detail, the Scapula-Humeral Mechanism
Describe the
in relation to movement of abduction. Discuss
1. Attachments
2. Nerve supply important clinical conditions

Actions of Trapezius, Latissimus Dorsi, Rhomboid

139 141

major and minor. Describe Rotator Cuff Muscles, state their

Mention the neurovascular supply of pectoral region Anatomical significance and explain Rotator Cuff Human
Anatomy
and Correlate with important clinical conditions. MS-A-009 Tendinitis Rotator Cuff
Describe superficial muscles of the back with their Clinical correlates of shoulder joint. (shoulder joint Integrate with
origin, insertion, nerve supply and actions. stability, dislocation and shoulder pain) Surgery
Describe the Osteology of Clavicle Describe the formation of Brachial Plexus; Infra and

(Morphological features, side determination, Supraclavicular parts. Discuss

attachments, ossification) Brachial plexus injuries

Demonstrate and identify the formation of brachial
Describe the correlates functions of Clavicle
plexus and its branches
(clavicle fracture, its role in terms of weight
List the branches of brachial plexus and give their
transmission of upper limb, compression of
areas of distribution and muscles they innervate
neurovascular structures) Human Nerves of
MS-A-010 Enlist and tabulate the muscles of anterior
Describe the Osteology of Scapula (morphological Bones of Anatomy Upper Limb
Upper compartment of arm with their attachments, nerve
MS-A-004 features, attachments, ossification) Human
Limb: Clavicle supply and action.
Anatomy
Determine the side and identify the landmarks of &
Scapula
Identify & Describe Musculocutaneous Nerve in
scapula
terms of its Origin, Course, Termination, Relations,
Describe the movements of Scapula
Branches, and distribution.
associated with movements of Shoulder Girdle
Describe and illustrate the cutaneous innervation of
Tabulate the muscles of scapular region and give
the arm.
their attachments, nerve supply and action
Describe the Brachial Artery in terms of its course,
Tabulate the attachments, origin, insertion,
relations, branches, and distribution
innervation, and actions of Anterior Axio-
Tabulate the attachments, innervation, and actions
appendicular Muscles
of Triceps brachii as a muscle of Blood supply of
Bones of MS-A-011
Describe the Sternoclavicular Joint in terms of Posterior Fascial Compartment of Arm arm
thorax, Joints
MS-A-005 articulating surfaces, ligaments, articular disc, Human of Upper Limb: Identify & Describe the Profunda Brachii Artery
nerve supply. Anatomy Sternoclavicula Human
giving its course, relations, branches, and
r Joint Anatomy
Develop clear concepts of the topographical distribution
anatomy of Axilla and its contents Describe Cubital Fossa with emphasis on its
Describe the boundaries of Axilla. (Identification of boundaries, contents, and clinical significance
MS-A-006 Human
Axila MS-A-012 Demonstrate surface marking of superficial veins of
muscles forming the boundaries of axilla) Anatomy Muscles of Arm
arm and forearm for IV (Intra venous) injections
List the contents of Axilla
Perform dissection/ Identify the Axilla and its Demonstrate biceps brachi reflex, triceps reflex and

140 142
 brachioradialis reflex extensor expansion
Determine the side and identify the landmarks of Demonstrate the attachments and actions of the
radius and ulna. muscles of hand
Describe the Osteology of Radius (Side Identify the muscles and neurovasculature of palm.
MS-A-013 Determination, morphological features, Bones of Explain the morphology and tabulate the
Human
Forearm
attachments). Anatomy attachments, innervation and actions of intrinsic
Hand
Describe the Osteology of Ulna (Side Determination, muscles of hand. &
morphological features, attachments). Explain the fascial spaces of palm and pulp space of Actions of
MS-A-025 Human
Muscles of
Describe osseofascial compartment of forearm. fingers Anatomy
Muscle of Upper Limb as
Tabulate flexor and pronators muscles of forearm, Describe Dupuytren contracture, mallet finger and a Functional
MS-A-014 Anterior/Flexor
Unit
their attachments, actions and nerve supply. Compartment buttonaire deformity.
of Forearm
Describe the action of paradox with examples Describe hand as a functional unit. (position of hand,
Tabulate the attachments, innervation, and actions Muscle of movement of thumb and fingers while performing
Lateral and
of Extensor Muscles of the Forearm different functions)
MS-A-015 Posterior/Exten
Tabulate the attachments, innervation, and actions sor Discuss cupping of hand and fist formation.
Compartment Draw the Radial Artery course, relation and
of Lateral Muscles of the Forearm
of Forearm
Identify the muscles and nerves of flexor and termination in hand with its clinical significance in

extensor compartments of forearm the region

Describe the Ulnar Artery’s Course, relation and Blood vessels
Describe and illustrate the cutaneous innervation of Nerves of Human
MS-A-016 Human MS-A-026 of forearm and
Forearm termination in hand with its clinical significance in Anatomy
the Forearm Anatomy hand
the region
Describe ulnar, median and radial nerves in fore
arm. Describe the formation, branches, and areas of
distribution of Superficial and Deep Palmar Arch
Describe the Origin, Course, Relations, and
Describe the course, relations and branches of Nerves of
branches of Ulnar and radial Artery in Forearm MS-A-027 Human
forearm and
Ulnar, Median and Radial Nerves in the Hand Anatomy
Describe the Origin, Course, Relations and list the hand
tributaries of veins of Forearm. Describe the First Carpometacarpal Joint in terms
MS-A-017 Blood supply of
forearm of; Type, Variety, Articular Surfaces, Ligaments,
Surface marking of Brachial artery, Cephalic, Relations, Blood Supply, Innervation, movements.
Median cubital, Basilic Vein, Radial & Ulnar arteries, Demonstrate the movements of the 1st Human
MS-A-028 Joints of Hands
anterior &posterior interosseous artery carpometacarpal joint Anatomy

Identify the Extensor & Flexor Retinacula and Describe the Metacarpophalangeal &
Human Retinacula of
MS-A-018 describe their attachments and relations Anatomy Forearm interpharyngeal Joints in terms of; Type, Variety,
MS-A-019 Demonstrate the formation of carpal tunnel and Human Articular Surfaces, Ligaments, Relations, Blood

143 145

identify the contents Anatomy- Carpal tunnel Supply, Innervation & Movements
Integrate with syndrome
Describe Carpel Tunnel Syndrome Palpate the arteries of the upper limb on a subject Integrate with
surgery
Medicine
Describe the features, attachments, relations and
Identify the topographical features of upper limb in a
structures passing under Flexor
cross-sectional model/ specimen.
Retinaculum
Demonstrate and identify the anatomical landmarks Integrate with
MS-A-029 Skills
Describe the Origin, Course, Relations, and Radiology
of upper limb on radiographs/ CT (Computed
branches of Ulnar Artery in Forearm Human tomography)/ MRI (Magnetic resonance imaging)
Describe the Origin, Course, Relations and list the Anatomy Forearm: Blood
Mark the anatomical landmarks and surface marking Human
tributaries of veins of Forearm supply and
Venous on a subject/ simulated model Anatomy
Surface marking of Brachial artery, Cephalic, drainage
LOWER LIMB
Median cubital, Basilic Vein, Radial & Ulnar arteries,
MS-A-020 THEORY
anterior &posterior interosseous artery
Describe the Elbow Joint in terms of articular CODE SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
surfaces, type, variety, ligaments, muscles Draw and label the Parts of the hip bone, with its
producing movements, blood supply {Anastomosis Human attachments.
Anatomy Joints of Upper
around elbow joint}, nerve supply and radiological Limbs: Elbow Describe the parts, attachments of hip bone
imaging. Joint MS-A-030 Identify the parts and bony features of the hip bone, Human
Hip Bone
Anatomy
Describe Carrying Angle and justify its importance in Integrate with with its attachments, important relations
MS-A-021
limb movement Surgery Demonstrate the side determination of hip bone, its
Describe the Radioulnar Joints in terms of articular bony features, attachments
surfaces, type, variety, ligaments, muscles Describe the parts, attachments, side determination
producing movements, nerve supply and of femur
radiological imaging. Identify the parts and bony features of the femur,
Joints of Upper
Human Limbs: with its attachments.
MS-A-022
Describe the wrist joint in terms of articular surfaces, Anatomy Radioulnar MS-A-031 Demonstrate the side determination of femur, its Human
Femur
Joint Anatomy
type, variety, ligaments, muscles producing bony features, attachments, and important relations
movements, nerve supply and radiological imaging. (correlate these with fractures)
Demonstrate mechanisms of movements of Describe coxa Vara and coxa valga and their clinical
Pronation & Supination significance
Describe the features of Interosseous Human Interosseous Describe the extent, attachments, and modifications
MS-A-023
Membrane with structures that pierce through it Anatomy membrane of Fascia Lata
MS-A-032 Human
Fascia Lata
Describe the features and explain the importance of Fascia & Demonstrate the attachment of fascia Lata, iliotibial Anatomy
MS-A-024 Human Muscles of
Fibrous Flexor Sheaths, synovial flexor sheaths and tract
Anatomy Hand
144 146
 Describe the cutaneous nerves and vessels of thigh Describe and identify the lumbar and sacral plexus
Draw and label the cutaneous nerve supply of thigh and its branches supplying the lower limb
Describe the formation, course, relations, tributaries, Describe the cutaneous nerve supply and
and termination of the superficial veins lymphatics of the region
Explain the anatomical justification of venesection, List the structures passing through the greater and
varicose veins, and saphenous venous grafts Human Neurovascular lesser sciatic foramen.
MS-A-033
Describe the lymphatic drainage of the region with Anatomy Supply of thigh Describe the muscles of gluteal region with their
special emphasis on afferent and efferent of inguinal proximal and distal attachments, innervation, and
lymph nodes actions
Identify the superficial and deep lymph nodes Identify the muscles of gluteal region with their
Explain the anatomical justification for enlargement proximal and distal attachments
of inguinal lymph nodes Describe the origin, course, relations, branches/
Describe and identify the Boundaries and contents tributaries, distribution, and termination of
of femoral triangle MS-A-040 neurovascular structures of gluteal region Gluteal Region
Draw and label the Boundaries and contents of Demonstrate the actions of the muscles of gluteal
femoral triangle region
Identify the femoral sheath with its Explain the anatomical basis of the consequences of
compartments wrongly placed gluteal intramuscular injections Integrate with
Human
Describe the formation of femoral sheath and its Femoral Damage to Gluteus medius & minimus due to Medicine
MS-A-034 Anatomy
Triangle &
significance poliomyelitis
Canal
Describe the formation of femoral canal and its Demonstrate and identify the origin, course,
contents and significance relations, branches/tributaries and termination of Human
nerves and vessels of gluteal region Anatomy
Describe the formation and significance of femoral
ring Describe the Attachments of muscles of posterior
Compare and contrast the anatomical features of compartment of thigh with the innervation and action
Integrate with
femoral and inguinal hernias Surgery Identify the muscles of posterior compartment of Human
Muscles of
thigh with their proximal and distal attachments Anatomy
Tabulate the muscles of anterior compartment of MS-A-041 Posterior
thigh with their attachments, nerve supply and Demonstrate the actions of muscles of posterior Compartment
Muscles of of Thigh
actions compartment of thigh
MS-A-035 Human Anterior
Anatomy Compartment Describe the anatomical basis of signs and Integrate with
Demonstrate and identify the muscles of anterior
of Thigh symptoms of sciatica. Surgery
compartment of thigh with their proximal and distal
Describe the origin, course, relations, branches, Blood supply of
attachments MS-A-042
distribution, and termination of Profunda femoris Human Posterior

147 149

Demonstrate the actions of muscles of anterior artery Anatomy compartment

thigh
compartment of thigh Describe blood supply on back of thigh

Explain the anatomical basis of psoas abscess Integrate with Describe the origin, course, relations, branches,
Surgery Human
distribution, and termination of sciatic nerve
Identify and demonstrate the nerves and vessels of Anatomy
MS-A-043 Describe the anatomical basis, signs and Sciatic Nerve
anterior compartment of thigh along with their
symptoms of compression of or injury to sciatic
branches
nerve Integrate with
Describe the origin, course, relations, branches, Surgery
Describe the hip joint with its type, articulations,
distribution, and termination of femoral artery Neurovascular
ligaments, stabilizing factors
Describe the origin, course, relations, tributaries, supply of
MS-A-036 Human
Anterior Movements, and neuro-vascular supply with clinical
area of drainage and termination of femoral vein Anatomy
Compartment
significance.
Describe the origin, course, relations, branches, of Thigh
distribution, and termination of femoral nerve Perform the movements of hip joint at various
Tabulate the muscles of anterior compartment of angles and be able to describe the muscles
MS-A-044 Hip Joint
thigh with their attachments, nerve supply and producing the movement. Human
actions. Anatomy
Describe the formation, boundaries, contents of Discuss important associated clinical conditions
adductor canal (Hip dislocation, Arthritis, Hip joint stability and
MS-A-037 Adductor Canal
Identify and demonstrate the boundaries and Trendelenburg sign) movements, and neuro-
contents of adductor canal vascular supply with clinical significance.
Describe Muscles of medial compartment of thigh Human
Anatomy Describe the Boundaries and contents of popliteal
with their proximal and distal attachments,
fossa. Discuss clinical correlates (Popliteal
innervation and actions Muscles of
Medial aneurysm, Palpation of Popliteal artery, semi
MS-A-038 Identify the muscles of medial compartment of thigh
Compartment membranous bursa swelling and Baker’s cyst
with their proximal and distal attachments of Thigh
Draw and label boundaries and contents of popliteal
Demonstrate the actions of the muscles of the
MS-A-045 fossa Human
Popliteal Fossa
compartment on self/ subject Anatomy
Identify the boundaries and contents of popliteal
Describe the origin, course, relations, branches/
fossa
tributaries, distribution, and termination of Neurovascular
Describe the origin, course, relations,
neurovascular structures of medial compartment of supply of
MS-A-039 Medial branches/tributaries, distribution and termination of
thigh
Human Compartment popliteal artery and vein
Identify the nerves and vessels of medial Anatomy of Thigh
Describe parts of tibia and fibula, with their Human Knee Joint
compartment of thigh along with their branches MS-A-046
attachments, important relations and side Anatomy

148 150
 determination joints with their types, articulation, movements, Human foot
Anatomy
Identify the parts and bony features of the tibia & ligaments.
fibula, their bony features, attachments, important Describe the formation, components, stabilizing and
relations. maintaining factors of the arches of foot Integrate with
MS-A-055 Arches of foot
Draw and label Parts of patella with its attachments Describe the clinical significance of arches of foot Orthopedics

Describe features of patella, and name the factor with respect to flat foot, claw foot.
responsible for stabilizing Patella Describe the fibrous flexor sheaths, extensor Human Retinacula of
MS-A-056
Describe the knee joint with its type, articulations, expansions and synovial flexor sheaths Anatomy foot

ligaments, movements, and neuro-vascular supply Describe the origin, course, relations,
Explain the mechanism of locking and unlocking of branches/tributaries, distribution, and termination of
knee joint with the foot on ground and off the plantar vessels
ground Identify the nerves and vessels on the foot along
with their branches
Describe the attachments and role of popliteus in Describe the cutaneous nerves of foot
locking and unlocking of the knee joint MS-A-057 Draw and label the cutaneous nerve supply and Human Neurovascular
Anatomy supply of foot
Describe the factors responsible for stability of knee dermatomes of foot
joint. Discuss important associated clinical Identify the nerves and vessels in the sole of foot
conditions. along with their branches
Describe the Muscles of anterior, lateral, and Describe the palpation of dorsalis pedis artery
posterior compartments of leg with their proximal & Muscles of leg &explain the clinical significance of dorsalis pedis
distal attachments, innervation, and actions artery
MS-A-047
Identify the muscles of anterior, lateral, and posterior Describe the surface anatomy, course, relations,
compartments of leg with their proximal and distal Neurovascular
tributaries, and communications of the superficial
supply of Leg
attachments veins of the lower limb
Arterial and
Describe the origin, course, relations, MS-A-058 Draw a concept map of the superficial veins of lower Human Venous
branches/tributaries and termination of nerves and Human limb Anatomy drainage of
Anatomy lower limb
vessels of anterior, lateral, and posterior List the factors favoring venous return of the lower
compartments of leg- Compartment Syndrome, Foot Neurovascular limb
MS-A-048
Drop supply of Leg Explain the anatomical basis of the formation,
Describe the cutaneous nerves and veins of leg. and signs and symptoms of deep venous Integrate with
Draw and label the cutaneous nerve supply and MS-A-059 thrombosis Surgery
Human Gait
dermatomes of leg Discuss Clinical correlations of Lower Limb Arteries Integrate with
MS-A-049 Identify the extensor, flexor, and peroneal retinacula Flexor, (palpation of femoral, popliteal, posterior tibial & Medicine

151 153

and demonstrate the structures related to them Extensor, and dorsalis pedis arteries, collateral circulation,
peroneal
Describe the attachments, relations, and structures intermittent claudication, occlusive arterial disease)
Reticula
passing under cover of, extensor, Lymphatic
Draw a concept map of the lymphatic drainage of drainage of
peroneal, and flexor retinacula MS-A-060 Human
lower limb lower
Anatomy
Identify and demonstrate the nerves and vessels of limb
anterior, lateral, and posterior compartments of leg Draw and label the cutaneous nerves & dermatomes

along with their branches of the lower limb

Describe the formation of noncalcareous

(Achilles tendon) Discuss clinical correlates of Lower limb nerves Cutaneous
MS-A-061 (Femoral nerve injury, Sciatic Nerve injury, Common dermatomes &
Describe the articulations, muscles and nerve Human Tibio-fibular nerve supply of
MS-A-050
supply and movements at Tibiofibular joints Anatomy Joint fibular, tibial & obturator nerve injury) lower limb

Describe the ankle joint with its type, articulations,

ligaments, movements, and nerve supply Describe the anatomical basis of knee jerk, ankle
Human
Describe the factors stabilizing the ankle joint. jerk, and plantar reflex Anatomy
MS-A-051 Human Ankle Joint Demonstrate the surface marking of nerves and
Discuss important associated clinical conditions.
Anatomy
Identify and demonstrate the articulating surfaces vessels of lower limb
Demonstrate the surface marking of bony landmarks Topographical
and ligaments of ankle joint
and
Describe the formation, attachments, and clinical of lower limb radiological
Human MS-A-062
Anatomy Identify the topographical features of lower limb in a anatomy of
significance of plantar aponeurosis
MS-A-052 Plantar Fascia lower
Explain the anatomical basis of the signs and cross-sectional model
Integrate with limb
symptoms of plantar fasciitis. Orthopedics Demonstrate and identify the features of bones and Integrate with
joints of lower limb on radiograph/ CT scan/ MRI Radiology
Identify the parts and bony features, attachments,
and important relations of the articulated foot Describe the common fractures of the following

Describe the muscles of the dorsum and sole of foot bone with the risk factors, clinical presentations, and

with their proximal & distal attachments, innervation management:

and actions emphasizing the role of interossei and 1. Clavicle

MS-A-053 lumbricals. 2. Humerus

Muscles of foot
Human MS-A-063 3. Radius Orthopedics
Draw and label the muscles of the layers of sole of Bone Fracture
Anatomy and trauma
4. Ulna
foot
5. Small bones of hand
Demonstrate and identify the muscles and tendons
6. Hip bone
with their proximal and distal attachments in the sole
7. Femur
of foot
8. Tibia
MS-A-054 Describe the interphalangeal, subtalar and midtarsal Small joints of

152 154
 9. Fibula three types of muscle tissue
10. Small bones of foot Describe Myosatellite Cells & their role in
Histology/
Describe the dislocations of the following joints with regeneration of muscle, hyperplasia, and Integrate with
the risk factors and clinical presentations, and brief hypertrophy of muscle fiber Pathology Functional
MS-A-072 Histology
management: Explain the histopathological basis of
Histopathology
Shoulder joint leiomyoma
MS-A-064 Orthopedics Joint Describe the light and electron microscopic structure
1. Elbow joint
and trauma Dislocation
2. Interphalangeal joint of hand of bone cells
Histology
3. Hip joint Describe the light and electron microscopic structure

4. Knee joint of compact and spongy bone Histology of

MS-A-073
5. Ankle joint Describe the histological justification for Osseous tissue
osteoporosis, Osteopetrosis Integrate with
THEORY
Describe the histological basis for bone repair after Pathology
EMBRYOLOGY & POST-NATAL DEVELOPMENT TOTAL HOURS = 06 fractures.
CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC Compare and contrast the microscopic features of
compact and spongy bone
Name the molecular and genetic factors involved in
Explain the characteristic features of ossification
the development of musculoskeletal system MS-A-074 Histology Histology of
(Intramembranous & Endochondral ossification)
Bone
Describe the development of skeletal muscle and Describe the zones seen in an epiphyseal growth
MS-A-065 innervation of axial skeletal Muscles-developmental Human Development plate
Embryology of Muscles
basis of myotome Describe the metabolic role of bone - Integrate with
Medicine
Briefly discuss the development of cardiac and MS-A-075 Functional
Describe the clinical presentation of osteoporosis, Integrate with Histology of
smooth muscle (Detail to be covered in respective
osteopenia Orthopedics Bone
modules later).
Describe the microscopic and ultramicroscopic
structure of all types of cartilage
Describe the process of limb development and limb
MS-A-066 Human Development Compare and contrast the structure of cartilage and
growth
Embryology of Limb MS-A-076 bone matrix Histology of
Histology
Cartilage
Describe the embryological basis of cutaneous Tabulate the differences between three types of
innervation of limb Development cartilage
MS-A-067 Human
of Nerve
Describe the embryological basis of blood supply of Embryology
supply of limbs
Describe the histological basis for bone & Cartilage Mechanism of
limbs and concept of axial artery MS-A-077 Histology
growth and repair Bone growth

155 157

Describe the embryological basis of congenital Human

anomalies related to muscular system. Embryology

Describe the clinical presentations and

HISTOLOGY TOTAL HOURS = 08
embryological basis of; CODE
i. Amelia Congenital
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
MS-A-068
ii. Meromelia anomalies of Draw and label the histology of skeletal muscle
Integrate with
limbs Histology of
iii. Phocomelia Paedriatics MS-A-078 Draw and label the histology of smooth muscle Histology
Muscles
iv. Cleft Hand and Foot Draw and label the histology of cardiac muscle
v. Polydactyly, Brachydactyly, Syndactyly Draw and label the histological picture of compact
vi. Congenital club foot bone
MS-A-079 Histology of
Histology
Describe the developmental process of cartilage and Draw and label the histological picture of spongy Bones
bone Human Development bone
MS-A-069
Describe the process of histogenesis of cartilage Embryology of Cartilage Draw and label the microscopic structure of hyaline
and bone cartilage
List the factors contributing to the development of Draw and label the microscopic structure of elastic
MS-A-080 Histology of
Histology
Axial skeletal system cartilage Cartilage
Describe the clinical picture and explain the Development Draw and label the microscopic structure of fibro
MS-A-070 Human
embryological basis of Axial skeletal anomalies of Axial cartilage
Embryology
skeleton
Describe the developmental process of Vertebral
NORMAL FUNCTION
Column
THEORY
THEORY MEDICAL PHYSIOLOGY TOTAL HOURS = 32
CODE
MICROSCOPIC ANATOMY TOTAL HOURS = 06 SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
CODE
Explain the Physiological basis of membrane
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC Diffusion /
MS-P-001 potential Equilibrium
Describe the microscopic structure and
Histology Explain diffusion potentials of Na & K Potentials
ultramicroscopic structure of skeletal muscle
Define Nernst potential
Explain the basis of myasthenia gravis. Integrate with
Explain Physiological Basis of Nernst potential Medical
Medicine
Physiology
Describe the microscopic and Write the Nernst equation.
MS-A-071 Nernst
MS-P-002
ultramicroscopic structure of cardiac muscle Histology of Calculate Nernst potential for Na & K potential
Describe the microscopic and Muscles
Histology Explain the effects of altering the concentration of
ultramicroscopic structure of smooth muscle Na+, K+, Ca on the equilibrium potential for that ion
Compare and contrast the histological features of
156 158
 Describe the normal distribution of Na+, K+, Ca and Tetanization. Medical muscle
Physiology contraction
Cl- across the cell membrane Describe staircase effect/Treppe phenomena
Explain physiological basis of Goldman equation Goldman
MS-P-003 Discuss the mechanism of skeletal muscle fatigue.
Equation
Clarify the role of Goldman equation in generation of Explain the remodeling of skeletal muscle to match
Resting Membrane Potential (RMP). the function. Describe the development of macro
Describe the Physiological basis of generation of motor units in poliomyelitis.
RMP. Medical
Physiology
Explain the effects of hyperkalemia and Explain the physiological basis of rigor mortis Integrate with
Hypokalemia on the Resting Membrane Potential Resting Forensic
MS-P-004 (RMP) Membrane Medicine
Potential in Describe the physiological anatomy of Neuro
Name the membrane stabilizers Neurons
Muscular Junction (NMJ) Medical
Medical
Explain the physiological basis of action of Local Mechanism of Neuromuscular transmission & Physiology
Physiology
Anesthetics. Integrate with generation of End Plate Potential
Anesthesiology Medical
Describe the Physiological anatomy of Neurons Explain features, pathophysiology & treatment of Physiology
Discuss the axonal transport MS-P-016 myasthenia Gravis Integrate with Neuromuscular
Medicine junction
MS-P-005 Enlist & give functions of Neuroglial cells Neurons Describe the enhancers or blockers of
Explain process of myelination in Central Nervous neuromuscular transmission at the neuromuscular Medical
System (CNS) & Peripheral Nervous System (PNS) Physiology
junction.
Classify neurons functionally.
Classification of Discuss the steps/ events of excitation contraction
MS-P-006 Classify nerve fibers according to Erlanger & Gasser Medical
Neurons &
coupling in skeletal muscle. Physiology
Classification Fibers
Differentiate between types of smooth muscles.
Define Action Potential
Medical Describe mechanism of smooth muscle contraction
Enlist the Properties of action potential
Physiology in comparison to skeletal muscle.
Describe the ionic basis of an action potential.
Explain the physiological anatomy of neuromuscular
Explain the phases of action potential. Action junction of smooth muscle
MS-P-007 Explain the effects of hyperkalemia and Potential of
Medical
Neurons MS-P-017 Explain the excitatory and inhibitory transmitters Smooth Muscle
Hypokalemia on the action potential. Physiology
secreted at Neuro Muscular Junction (NMJ) of
Draw monophasic action potential.
smooth muscles.
Explain absolute and relative refractory period Explain the depolarization of multiunit smooth

Explain the role of other ions in action potential. Role of other muscles without action potentials.
MS-P-008 ions in action Explain the local tissue factors and hormones that
Elaborate the effect of hypocalcemia on neuron
potential
159 161

excitability. can cause smooth muscle contraction without action

Explain Physiological basis& properties of Graded potential.
potential Explain the regulation of smooth muscle contraction
Draw & explain Physiological basis & properties of by calcium ions.
compound action potential. Explain membrane potential and action potentials in
Local /
MS-P-009 Contrast between action potential and graded Graded smooth muscles.
potential potentials Explain the phenomena of stress relaxation and
Describe the ionic basis of excitatory Post Synaptic reverse stress relaxation in smooth muscles.
Potential (EPSP), Inhibitory Post Synaptic Potential Explain the LATCH mechanism
(IPSP), End Plate Potential (EPP). Describe the significance of LATCH mechanism.
Classify and explain Physiological basis of different Explain the nervous and hormonal control of Smooth
types of synapses Muscle Contraction.
MS-P-010 Synapse
Elaborate how signal transmission takes place
THEORY
across chemical synapse
Medical
Explain the mechanism of conduction of Nerve Physiology MEDICAL BIOCHEMISTRY TOTAL HOURS = 30
CODE
impulse in myelinated and unmyelinated nerve Conduction of SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
MS-P-011
fibers. Nerve Impulse
Classify carbohydrates along with the structure and Classification
Elaborate significance of saltatory conduction MS-B-001 Biochemistry
biomedical importance of each class carbohydrates
Enlist the types of nerve injury
MS-B-002 Explain the isomerization of carbohydrates Biochemistry Carbohydrates
Explain Wallerian degeneration.
Describe the physical and chemical properties of
Describe the process of regeneration of nerve fiber. Nerve
MS-P-012 carbohydrates
Medical Degeneration Biochemistry
Describe the causes, features & pathophysiology of Physiology Differentiate between proteoglycan and
Multiple sclerosis, GB syndrome. Integrate with glycoproteins
Medicine
Describe the components of extracellular matrix:
Discuss the physiological anatomy of skeletal
1. Describe structure, functions and clinical
muscles.
Extracellular
Skeletal muscle MS-B-003 significance of glycosaminoglycans
MS-P-013 Differentiate b/w skeletal, smooth, and cardiac matrix
2. Discuss structure and functions of Fibrous
muscle Medical
proteins (collagen and Elastin) Biochemistry
Describe the structure of Sarcomere Physiology
3. Interpret diseases associated with them on
Differentiate between isometric and isotonic
Characteristics basis of sign/symptoms and data
MS-P-014 contraction by giving examples. of whole muscle
contraction 4. Interpret the importance of vitamin C in
Compare the fast and slow muscle fibers.
collagen synthesis
MS-P-015 Explain the mechanism of summation and Mechanics of

160 162
 5. Describe sources, active form, functions and Discuss briefly the therapeutic effect of drugs used Drugs in
MS-Ph-02 Myasthenia
deficiency diseases of vitamin C in myasthenia gravis.
Gravis
6. Identify the defects in collagen synthesis Discuss briefly the therapeutic effect of drugs used
MS-Ph-03 Local
based on given data (Ostegenesis as local anesthetics. Anesthetics
Imperfecta) Describe the hyperplasia, hypertrophy, and atrophy
Interpret genetic basis of Duchene muscular MS-Pa-01 of muscle fiber Muscle
remodeling
dystrophy Explain the histopathological basis of leiomyoma
Explain the transport and uptake of glucose in cells, Biochemistry Describe the histological basis of Duchenne Diseases of
MS-Pa-02
steps of glycolysis and citric acid cycle along with Muscular Dystrophy and myopathy. Muscle
enzymes, co enzymes and cofactors involved Describe the clinical presentation and histological
Pathology
Discuss the provision of energy to the muscles and justification for osteoporosis, osteopetrosis Diseases of
Biochemistry Glycolysis and MS-Pa-03
cells through glycolytic pathway and TCA cycle Describe the histological basis for bone repair after Bone
MS-B-004 Tricarboxylic
Explain the hormonal and allosteric regulation of acid cycle fractures
Biochemistry (TCA)
glycolysis and TCA Describe the histological basis for cartilage growth Disease of
MS-Pa-04
Describe the digestion and absorption of proteins in Protein and repair Cartilage

MS-B-005 mouth, stomach and small intestine. Biochemistry Digestion &

Transport AGING
Discuss the uptake of amino acids by cells across cell
THEORY
Explain following reactions with enzymes involved in
it: TOTAL HOURS = 04
CODE SPECIFIC LEARNING OUTCOMES
1. Transamination DISCIPLINE TOPIC
Reactions
MS-B-006 2. Deamination decarboxylation Biochemistry involve in Discuss the effect of age on bone fragility and its
catabolism MS-Ag-01 Bone
3. Deamidation implications with management.
4. Trans deamination. Discuss the effect of age on loss of cartilage
MS-Ag-02 Cartilage
5. Oxidative deamination. resilience and its implications and management
Role of pyridoxal phosphate, glutamate, glutamine, Transportation Discuss the effect of age on Muscular strength and
MS-B-007 Biochemistry of ammonia to MS-Ag-03 Muscle
alanine its implications and management
the liver Geriatrics/
Illustrate steps of urea cycle with enzymes and its Medicine/
Biochemistry
MS-B-008 importance Explain the protective effect of estrogen (female sex
Discuss ammonia intoxication Biochemistry Urea cycle hormone) on bone mineral density and relate it to Effect of
MS-Ag-04 estrogen on
Interpret different types of hyperammonia on basis increased prevalence of postmenopausal fractures
MS-B-009 BMD
of sign symptoms and data in women.
Discuss the catabolic pathways of aliphatic, Protein
MS-B-010 Biochemistry
aromatic, branched chain, sulfur containing, metabolism
163 165

hydroxyl group containing amino acids with the DISEASE PREVENTION AND IMPACT
products formed and enzymes and vitamins involved
THEORY
in them
TOTAL HOURS = 14+3=17
Interpret the following on basis of given data: CODE SPECIFIC LEARNING OUTCOMES
1. Phenylketonuria DISCIPLINE TOPIC

2. Tyrosinemia Explain causes of low back pain

Inborn errors of MS-CM-001
MS-B-011 3. Albinism Describe prevention of low back pain Back Pain
Biochemistry amino acid
4. Homocystinuria metabolism Describe work related musculoskeletal disorders
Community
5. Maple syrup urine disease addition with its burden/epidemiology Medicine and
6. Alkaptonuria Identify risk factors of Musculoskeletal disorders Public
MS-CM-002 Work related
Health
MSD at workplace Musculoskeletal
disorders
Describe prevention of exposure to risk factors
related to workplace
TOTAL HOURS=06
CODE SPECIFIC LEARNING OBJECTIVES Describe MSD related to mobile addition with its
DISCIPLINE TOPIC burden/epidemiology
Demonstrate and categorize the following Describe MSD related to mobile usage (Text neck,
movements: Pushing against the wall, Biceps curls, Trigger thumb, DeQuervain Syndrome, Carpel
squats, yoga chair pose, standing on toes, running Physiology Locomotion Tunnel Syndrome) Community
MS-P-018
on an inclined treadmill, yoga tree pose, deadlift as MS-CM-003 Medicine and
MSD related to
Public
isotonic and isometric skeletal muscle contraction. mobile usage
Identify risk factors related to MSD due to excessive Health
Estimation of total proteins by kit method/dipstick mobile usage.
MS-B-012 Total proteins
methods. Describe the preventive strategies for mobile
MS-B-013 Estimation of albumin and globulin Albumin/
addiction-related MSD.
globulin
Describe the application of ergonomics in MSD
PATHOPHYSIOLOGY AND PHARMACOTHERAPEUTICS MS-CM-004 Ergonomics
related to the above disorders.
THEORY Describe the concept of non-communicable
MS-CM-005 Noncommunic
TOTAL HOURS = 4+7=11 Musculoskeletal diseases Community able disease
CODE SPECIFIC LEARNING OBJECTIVES Medicine and
Identify the risk factors in the community for
DISCIPLINE TOPIC Public
Osteoporosis Health Risk factor
Explain the mechanism by which drugs can
Drugs acting MS-CM-006 Learn and apply interventions to prevent the risk assessment of
stimulate NMJ. Pharmacology on Musculoskeletal
MS-Ph-01 factors for various musculoskeletal diseases in the diseases
Explain the mechanism by which drugs can block & Neuromuscular
Therapeutics Junction (NMJ) community.
NMJ.
MS-BhS-001 Identify and deal with the various psychosocial Behavioral Psychosocial

164 166
 aspects of Musculoskeletal conditions (such as Sciences factors Describe the external features of heart.
influencing
Osteoarthritis, Osteomyelitis, Rheumatoid arthritis, List various chambers of heart mentioning their
chronic
Gout, chronic back pain, psychosomatic complaints) illnesses salient features and openings.
and Neuromuscular conditions (Muscular dystrophy, Describe the arterial supply of heart: coronary arteries Human
Myasthenia Gravis, Sclerosis) on Individual, Family and their distribution with special emphasis on Anatomy
and Society collaterals established during ischemia.
Identify the psychosocial risk factors as mediating Describe the sites of anastomosis between right and
factors between illness and its effect. Psychosocial left coronary arteries with the participating vessels.
Impact of
MS-BhS-002 Discuss the role of psychological variables like Integrate
Disease and its Discuss the anatomical correlates of cardiac arterial with
coping, social support, and other health cognitions in management
supply cardiology/
mediating between illness and its effect. Medicine
Describe the anatomical correlates of
electrocardiography, cardiac referred pain. Integrate with
Cardiology/
Describe the anatomical basis for angioplasty, and
Medicine
coronary grafts.
Describe the features of angina pectoris and
CV-A-003 myocardial infarction and correlate them anatomically Heart

Describe the venous drainage of heart.

Describe the alternative venous routes to the heart
Identify the vessels supplying the heart with their
origins/terminations. Human
Anatomy
Describe the formation, relations, and distribution of
cardiac plexus.
Describe components and significance of fibrous
skeleton of heart
Describe the cardiac valves
Explain the anatomical basis for valvular heart Integrate with
Cardiology/
diseases
Medicine
Perform surface marking of various anatomical Human
landmarks of heart and great vessels Anatomy

Perform percussion and auscultation of heart Integrate with

Medicine
Identify the salient features of heart and great vessels Integrate with
Radiology

167 176

on Computed tomography/ Magnetic Resonance

NORMAL STRUCTURE
Imaging CT/ MRI

THEORY THEORY
EMBRYOLOGY & POST-NATAL
GROSS ANATOMY TOTAL HOURS = 10 TOTAL HOURS = 14
DEVELOPMENT
CODE CODE
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC
Define mediastinum giving its boundaries and Describe the early development of heart and blood Human
compartments. List the contents of its various CV-A-004 vessels Embryology
Introduction
compartments. Describe the development of pericardial cavity Human
Embryology
Describe the formation, tributaries, and termination of
superior vena cava Define parts of primitive heart tube and give its folding
Describe the formation, branches, and relations of
Describe the development of various chambers of Human
ascending aorta, aortic arch and descending thoracic Embryology Development
CV-A-005 heart with emphasis on their partitioning
aorta. of Heart
Human Identify various parts of developing heart tube and
CV-A-001 Discuss the distribution of ascending aorta, aortic Mediastinum
Anatomy structures derived from them during embryonic and
arch and descending thoracic aorta in reference to
fetal life (Models and specimens)
their branches
Describe the embryological basis of dextrocardia and
Describe formation, course and tributaries of Human
ectopia cordis Embryology
azygous, hemizygous and accessory hemizygous
Describe the partitioning of primordial heart:
veins.
Describe the course, relations, and distribution of atrioventricular canal and atrium

vagus and thoracic splanchnic nerves in relation to Describe the development of sinus venosus
nerve supply of heart. List clinically significant types of atrial septal defects
Describe Pericardium and its parts with emphasis on along with their embryological basis and features. Integrate with Development
Pediatrics
Describe probe patent foramen ovale of Heart and
their nerve supply. CV-A-006 Development
Human Describe the partitioning of truncus arteriosus and
Describe the pericardial cavity mentioning transverse of Lymphatic
Anatomy
bulbus cordis System
and oblique sinuses. Discuss their clinical significance Human
Describe the anatomical correlates of various Describe the formation of ventricles and Embryology
CV-A-002 Pericardium
pericardial conditions like pericardial rub, pericardial interventricular septum
pain, pericarditis, pericardial effusion, and cardiac Integrate with Describe the clinical features and embryological basis Integrate with
tamponade. Medicine of ventricular septal defects Pediatrics

Describe the anatomical basis for Paracentesis Describe the development of cardiac valves and Human
/pericardiocentesis. conducting system. Embryology

175 177
 Describe the development of lymphatic system Human system (Lymph capillaries, Lymph vessels & System
Embryology
Lymphatic duct)
Describe the embryological correlates and clinical
presentation of developmental defects of heart:
Integrate
Tetralogy of Fallot, Patent ductus arteriosus, Unequal with
division of arterial trunks, Transposition of great Pediatrics
HISTOLOGY TOTAL HOURS = 03
vessels and Valvular stenosis, Coarctation of aorta CODE
CV-A-007
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Describe the formation and fate of pharyngeal arch Human Development
arteries Embryology of Arteries Histological
Identify, draw and label histological structure of features of
CV-A-018
Describe the anomalies of great arteries emerging Integrate with Histology
cardiac muscle Cardiac
Cardiology/
from heart: Coarctation of aorta, anomalous arteries Muscle
Medicine
Describe the development of embryonic veins Identify, draw and label histological sections of elastic Histological
associated with developing heart: Vitelline veins, CV-A-019 artery, muscular artery, arterioles, vein, capillaries and Histology features of
Blood
Umbilical Veins and Common cardinal vein and their sinusoids Vessels
fate
CV-A-008 Describe the formation of superior & inferior vena Human Development NORMAL FUNCTION
Embryology of Veins
cava and portal vein with their congenital anomalies THEORY
With the help of diagrams illustrate the development
MEDICAL PHYSIOLOGY TOTAL HOURS = 68
of superior vena cava, inferior vena cava and portal CODE
vein SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
List the derivatives of fetal vessels and structures: Explain the physiological anatomy of cardiac muscle.
Umbilical vein, ductus venosus, umbilical artery, Human
Explain the functional importance of intercalated
Embryology
foramen ovale, ductus arteriosus discs.
CV-A-009 Fetal Vessels
Describe Fetal and neonatal circulation mentioning Discuss the properties of cardiac muscles.
Integrate with & Circulation
transitional neonatal circulation with its clinical Pediatrics/ Describe and draw the phases of action potential of
implication Obgyn
ventricle.
Cardiac
List clinically significant types of atrial septal defects CV-P-001 Describe and draw the phases of action potential of Physiology
Muscle
along with their embryological basis and features. SA node along with explanation of the mechanism of

Describe patent foramen ovale. self-excitation/ Auto rhythmicity of SA node.

CV-A-010 Congenital Define and give the duration of the Absolute and
Pediatrics
Describe the embryological correlates and clinical Heart defects
relative refractory period in cardiac muscle.
presentation of developmental defects of heart:
Describe the mechanism of excitation-contraction
Tetralogy of Fallot, Persistent ductus arteriosus,
coupling and relaxation in cardiac muscle.
Unequal division of arterial trunks, Transposition of
178 180

great vessels and Valvular stenosis Draw & explain pressure & volume changes of left

THEORY ventricle during cardiac cycle.

Explain & draw relationship of ECG
MICROSCOPIC ANATOMY (HISTOLOGY & TOTAL HOURS = 04
PATHOLOGY) (Electrocardiography) with cardiac cycle.
CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC Explain & draw the relationship of heart sounds with
cardiac cycle.
Describe microscopic structure of Heart wall
Enlist, draw, and explain the physiological basis of
(Endocardium, Myocardium, Epicardium)
atrial pressure waves in relation to cardiac cycle.
Describe histology of Cardiac skeleton, SA (sinoatrial)
Define & give the normal values of the cardiac output,
node, AV (atrioventricular) node, Purkinje fibers. Heart
CV-A-011 & stroke volume, end diastolic volume & end systolic Integrate with
Describe the microscopic and ultramicroscopic Medicine
Cardiac volume
structure of cardiac muscle emphasizing on Tubules, Histology
Muscle
sarcoplasmic reticulum and intercalated discs. Describe the Frank starling mechanism.
Identify, draw and label histological structure of Describe the autonomic regulation of heart pumping.
cardiac muscle Describe the effect of potassium, calcium ions &
Describe general histological organization of blood temperature on heart function.
vessels: Tunica intima, media and adventitia. Define chronotropic effect- positive and negative.
CV-A-012 Identify, draw and label histological sections of elastic Blood Vessels
Histology CV-P-002 Define the inotropic effect: positive and negative. Physiology Regulation of
artery, muscular artery, arterioles, vein, capillaries and Organization heart pumping
Define dromotropic effect: positive and negative
sinusoids Describe the location of adrenergic & cholinergic
Describe histological features of arteries: receptors in heart.
CV-A-013 Arteries
Muscular arteries, elastic arteries, Arterioles Histology Name the receptors present in coronary arterioles.
Describe histological features of veins and exchange Explain sympathetic & parasympathetic effects on
vessels: large veins, medium sized veins, venules, heart rate & conduction velocity
CV-A-014 Capillaries, and sinusoids Draw and explain the conducting system of heart
Histology Veins Conducting
Compare and contrast the light microscopic structure CV-P-003 Describe the physiological basis and significance of Physiology system of
of arteries and veins AV nodal delay. heart

Describe the histopathological basis of thrombus and Integrate with Thrombus/ Integrate with
CV-A-015 Embolus Explain the ectopic pacemaker Cardiology/M
embolus formation. Pathology
formation edicine
Explain the histological basis of arteriosclerosis and Arteriosclerosi Enlist, draw, and explain the physiological basis & Fundamental s
CV-P-004
CV-A-016 atherosclerosis. s give durations of waves, intervals, and segments of of ECG
atherosclerosis Physiology
Describe role of arterioles in hypertension Histology Hypertension normal ECG.
CV-A-017 Describe histological features of Lymph vascular Lymph Describe the standard limb leads, Augmented limb
vascular
179 181
 leads & precordial leads. flow occurs during changes in arterial pressure
Define Einthoven's Triangle & Einthoven's law. (metabolic & myogenic mechanisms).
Explain the physiological basis of upright T wave in Explain the role of autonomic nervous system for
normal ECG. regulating the circulation.
Describe the location and significance of J point in Explain the vasomotor center.
ECG. Explain the control of vasomotor center by higher
Physiology Nervous
Explain the physiological basis of current of injury. CV-P-010 nervous centers. Regulation of
Enlist the ECG changes in angina pectoris. Explain emotional fainting/vasovagal syncope. circulation
Integrate with
Enlist the ECG changes in myocardial infarction. Medicine Identify vessels constituting micro-capillaries.
Plot the mean cardiac axis. Enumerate hydrostatic and osmotic factors that
Enlist the physiological & pathological causes of right underlie starling’s hypothesis for capillary function.
axis deviation of heart. Physiology Explain the role of nervous system in rapid control of
Enlist the physiological & pathological causes of left arterial blood pressure.
axis deviation of heart Explain the regulation of arterial blood pressure
Describe the abnormalities of T wave and their Integrate with during exercise.
causes Medicine Enlist different mechanisms for short term regulation
Describe the effect of hypokalemia and hyperkalemia of arterial blood pressure.
on ECG Integrate Effect of Explain the role of baroreceptors in regulation of
CV-P- 005 with electrolyte on
Describe the effect of hypocalcemia and arterial blood pressure.
Biochemistry ECG
hypercalcemia on ECG. Explain the role of chemoreceptors in regulation of
Define tachycardia and enlist its causes. arterial blood pressure.
Integrate with
Define bradycardia and enlist its causes. Medicine CV-P-011 Make a flow chart to discuss the role of Atrial volume
reflexes/ Bainbridge reflex in control of blood Rapid control
Classify arrhythmias
Physiology of arterial
Explain the physiological basis of sinus arrythmia. pressure. blood
Explain the physiological basis of reflex bradycardia Make a flow chart to show the reflex responses to pressure
Physiology
in Athletes. increased blood volume which increase blood
CV-P- 006 Explain the carotid sinus syndrome. Cardiac pressure and atrial stretch.
arrhythmia
Enlist the causes of atrioventricular block. Describe the role of CNS ischemic response in

Explain the types of atrioventricular blocks. Integrate with regulation of the blood pressure.
Cardiology/
Explain the ECG changes in 1st, 2nd & 3rd degree Explain the Cushing reflex
Medicine
heart block. Explain the role of abdominal compression reflex to

Explain the cause, physiological basis & ECG increase the arterial blood pressure.
Physiology Make a flow chart to discuss the role of renin
changes in Stokes Adam syndrome/ventricular CV-P-012 Role of
182 184

escape. angiotensin system for long term control of blood Physiology kidneys in long
term
pressure.
Enlist the causes of premature contractions. Regulation of
Integrate with Make a flow chart to show the regulation of blood Arterial
Explain the causes and ECG changes of premature Cardiology/
pressure in response to increase in ECF (Extra Blood
Medicine
atrial contractions. Pressure
Cellular Fluid) volume.
Explain the physiological basis of pulses deficit. Physiology
Make a flow chart to show the regulation of blood
Explain the causes and ECG changes in Premature pressure in response to increase in salt intake.
Ventricular Contraction (PVC) Define cardiac output, cardiac index & venous return
Enlist the causes and ECG findings in Long QT with their normal values. Integrate with
Cardiology/
syndrome. CV-P-013 Cardiac output
Discuss the factors regulating cardiac output Medicine
Explain the causes, physiological basis, features, Integrate
ECG changes & management of premature with Discuss factors regulating venous return Physiology
Cardiology/
heartbeat. Medicine Explain the regulation of skeletal muscle blood flow at Skeletal
CV-P-014 Physiology muscle
Explain the causes, physiological basis, features, rest & during exercise.
circulation
ECG changes & management of atrial fibrillation. Explain the physiological anatomy of coronary
Explain the causes, physiological basis, features & circulation.
ECG changes of ventricular fibrillation. CV-P-015 Explain the regulation of coronary blood flow. Physiology Coronary
Explain the physiological basis, features & ECG Explain the physiological basis of angina, myocardial circulation
Physiology
changes of atrial flutter. & subendocardial infarction
Compare Flutter and Fibrillations Physiology Define & enlist different types of shock.
Explain the functional parts of circulation (arteries, Organization
CV-P-007 Physiology Explain the causes, features, and pathophysiology of
arterioles, capillaries, veins, venules). of Circulation
hypovolemic/hemorrhagic shock. Physiology
Explain the pressures in systemic & pulmonary
circulation. Explain the causes, features, and pathophysiology of
CV-P-008
Explain the types of Blood flow and significance of Physiology Blood flow septic shock.
Reynolds number. Circulatory
Explain the causes, features, and pathophysiology of
CV-P-016 shock
Describe local control of blood flow according to neurogenic shock. Integrate with
tissue needs. Pathology
Explain the causes, features, and pathophysiology of
Discuss humoral control of local blood flow.
Local & anaphylactic shock.
CV-P-009 Explain long term control of local blood flow. Humoral
Physiology Integrate with
Describe vascular control by ions and other chemical Control of Discuss the treatment of different types of shock.
Blood flow Medicine
factors.
Explain the different stages of shock.
Name the organs in which auto regulation of blood

183 185
 Explain the mechanisms that maintain the cardiac Physiology like cardiac disorders and hyperlipidemias
output & arterial blood pressure in non-progressive AGING
shock.
THEORY
Enlist different types of positive feedback
TOTAL HOURS = 05
mechanisms that can lead to the progression of CODE SPECIFIC LEARNING OBJECTIVES
shock. DISCIPLINE TOPIC
Enlist the different types of heart sounds and explain Discuss the effect of age on blood vessels with
CV-Ag-001 Hypertension
the physiological basis of each. reference to hypertension

Enlist the causes of 3rd and 4th heart sounds. Discuss the risk of cardiac attack in old age and Cardiac
CV-Ag-002
Physiology weather conditions Physiology/ Attack
CV-P-017 Explain the causes & physiological basis of murmurs Heart sounds Geriatrics/
Discuss the effect of age on valvular system of the
caused by valvular lesions. CV-Ag-003 Medicine
Valvular
heart.
diseases
Enumerate abnormal heart sounds and describe the Discuss the effect of age on neural conduction of the
Integrate with CV-Ag-004
physiological basis of each. Medicine heart in relation to arrythmia. Arrythmia
Physiology/ Role of
THEORY Discuss the protective role of female hormone against Obstetrics
CV-Ag-005 female
CVS diseases in women of reproductive age group and hormone on
MEDICAL BIOCHEMISTRY TOTAL HOURS = 21 Gynecology CVS disease
CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC PATHOPHYSIOLOGY AND PHARMACOTHERAPEUTICS

CV-B-001 Classify lipids Classification

Biochemistry THEORY
of lipids
Functions of TOTAL HOURS = 6+5=11
lipids & CODE SPECIFIC LEARNING OBJECTIVES
CV-B-002 Discuss the biomedical functions & properties of lipids Biochemistry
Properties of DISCIPLINE TOPIC
lipids
Classify types of thrombosis, embolism, and infarction
Classify fatty acids. Discuss the role of trans
CV-B-003 saturated, saturated, poly- and mono-unsaturated CV-Pa-001 Discuss the pathophysiology of thrombosis,
Biochemistry Classification Atherosclerosis
fatty acids in diet on lipid profile. of fatty acids embolism, and infarction
CV-B-004 Discuss lipid peroxidation and its significance Biochemistry Identify the types and causes of hypertension
Explain the biochemical and therapeutic roles of Discuss the clinical consequences of hypertension
CV-Pa-002 Pathology/ Hypertension
CV-B-005 eicosanoids (prostaglandins, leukotrienes, Biochemistry Eicosanoids and atherosclerosis Integrate
thromboxane, and prostacyclin) CV-Pa-003 with
Discuss the pathophysiology of shock Shock
medicine
CV-B-006 Interpret the disorders associated with impairment Biochemistry Hyperlipidemias Classify the types of heart failure
of lipoprotein metabolism especially atherosclerosis CV-Pa-004 Cardiac
CV-B-007 Biochemistry Cholesterol Identify the causes leading to heart failure Failure
and LDL (Low-Density Lipoprotein) oxidized

186 188

Identify the types of ischemic heart disease

Discuss the signs and symptoms of hyperlipidemia Ischemic
CV-Pa-005 Discuss the pathophysiology of different types of Heart
CV-B-008 Type I to V
Biochemistry ischemic heart disease Disease
hyperlipidemias
Interpret data related to hyperlipidemia
Explain the pathological causes of high & low cardiac Cardiac
CV-Pa-006
output. Output
Discuss the sources, biomedical importance, active
Fat soluble Discuss briefly the therapeutic effect of various Anti-
CV-B-009 states, deficiency and excess of fat-soluble vitamins: Biochemistry CV-Ph-001
vitamins hypertensive
Vitamins A.D. E and K antihypertensive drugs.
drugs
Discuss the sources, biomedical importance, active Discuss briefly the therapeutic effect of various Antianginal
CV-Ph-002
CV-B-010 states, deficiency and excess of water-soluble Water soluble antianginal drugs drugs
Biochemistry
vitamins
vitamins: Vitamins B group Discuss briefly the therapeutic effect of various Pharmacology Antiarrhythmic
CV-Ph-003
Discuss the sources, biomedical importance, active antiarrhythmic drugs mics drugs

states, deficiency and excess of minerals and trace Discuss briefly the therapeutic effect of drugs used in Drugs for
CV-B-011 Minerals and CV-Ph-004
Biochemistry cardiac failure. cardiac failure
elements especially zinc, Mg, Na, K, I, Ca, P, Se, S, trace elements
Cu DISEASE PREVENTION AND IMPACT

THEORY
TOTAL HOURS = 11+2=13
CODE SPECIFIC LEARNING OBJECTIVES
TOTAL HOURS = 10+3=13 DISCIPLINE TOPIC
CODE SPECIFIC LEARNING OBJECTIVES
Describe the various strategies and models to prevent Disease
DISCIPLINE TOPIC CV-CM-001 Prevention
diseases.
Record an electrocardiogram by correct lead Models

placement and connections a to identify normal heart Describe primordial prevention and its application to
CV-P-018 ECG
sound preventing CVS diseases.
CV-CM-002 Primordial
Determine the effect of posture and exercise on blood Depict the concept of primary prevention in context to Prevention
CV-P-019 Blood
pressure by auscultatory method. CVS and able to apply on CVS diseases.
Pressure Community
Measure the blood pressure of the subject by Physiology Blood Discuss the basic concept of health promotion and its Medicine and
CV-P-020 CV-CM-003 Public Health
palpatory and auscultatory methods. Pressure application to CVS. Promotion
Health
Examine arterial pulse to recognize normal
Discuss various methods of behavioural change Behavioural
CV-P-021 Arterial Pulse
characteristics of pulse. CV-CM-004 Change
interventions at community level.
Intervention
Examine neck veins to determine Jugular Venous
CV-P-022 JVP To apply secondary and tertiary preventions on CVS
Pulse (JVP) Secondary &
Perform cardiac markers Creatine Kinase and Lactate CV-CM-005 diseases (coronary heart disease, ischemic heart Tertiary
Performance disease, hypertension) Prevention
CV-B-012 Dehydrogenase (CK and LDH) Biochemistry
Interpretation
Interpret lab reports based on enzymes for diseases of Lab report
187 189
 Describe the concept of cardiovascular diseases as Define an intercostal space and give details of its
CV-CM-006 Noncommunic
non-communicable diseases able disease contents
Describe the anatomical features of typical & atypical
Identify the risk factors in the community for CVS
Risk factor thoracic vertebrae.
diseases.
CV-CM-007 assessment of Differentiate between typical and atypical vertebrae
Learn and apply interventions to prevent the risk Human Thoracic
CVS diseases
Re-A-006 Explain the thoracic part of the vertebral column (normal
factors in community. Anatomy Vertebrae
curvature, intervertebral joints & fascia of the back, blood
Identify and deal with the various psychosocial
supply, lymphatic drainage, nerve supply of back)
aspects of Cardiovascular conditions (such as Personal,
Psychosocial Associated Clinical conditions -Kyphosis, Scoliosis
CV-BhS-001 Hypertension, Coronary artery disease, Heart failure, Behavioral
and vocational Human
Arrythmias, and other cardiovascular conditions) on Sciences Describe the bony features of the sternum
issues Anatomy
Individual, Family and Society.
Emotional Describe the anatomical correlates of sternal biopsy. and Integrate with
CV-BhS-002 Psychological basis of emotional fainting & its impact Re-A-007 Sternum
fainting sternotomy Surgery

Describe the presentation of sternal fractures and Integrate with

correlate it anatomically Orthopedics

Define endo thoracic fascia Connective

Re-A-008 Describe the supra-pleural membrane with its tissue of
Thorax
attachments.
Classify the joints of the thorax mentioning their
articulations, movements with the muscle producing Joints of
Re-A-009 Human
them. Thorax
Anatomy
Describe the mechanics of inspiration and expiration
Describe the origin, course, relations and distribution of
intercostal nerves and vessels
Re-A-010
Describe the alternate routes of venous drainage in Neurovascular
supply of
blockage of superior/ inferior vena cava Thorax
Describe the cutaneous nerve supply and dermatomes Integrate with
of thorax. Medicine

Give anatomical justification of the manifestations of Human

Re-A-011 Cutaneous
herpes zoster infection on thoracic wall. Anatomy
nerve supply
Integrate with of Thorax
Discuss anatomical correlates of intercostal nerve block
Medicine
Re-A-012 Name the parts of diaphragm mentioning their Integrate with Diaphragm

190 197

attachments and neurovascular supply Anesthesia

NORMAL STRUCTURE
THEORY Explain the role of diaphragm in respiration

GROSS ANATOMY TOTAL HOURS = 24 Enumerate the diaphragmatic apertures with their
CODE Human
vertebral levels, mentioning the structures traversing
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC Anatomy
them.
Describe the anatomical features and neurovascular Human
supply of nasal cavity Anatomy Describe the pleura giving its parts, layers,

Upper neurovascular supply, and lymphatic drainage

Describe the anatomical features and neurovascular Human
Re-A-001 Respiratory Describe the pleural cavity giving its recesses and the
supply of pharynx Anatomy
tract
Re-A-013 lines of pleural reflection
Describe the anatomical features and neurovascular Human Pleural cavity
Human
supply of larynx Anatomy Describe the anatomical correlates of pleural pain Anatomy
Describe the anatomical features of the Trachea with its pleurisy, pneumothorax, pleural effusion
Re-A-002 Human
Trachea
extent, relations, neurovascular supply and lymphatics. Anatomy Integrate with
Describe the anatomical features, relations of lungs
Give the boundaries of thoracic cavity, superior and Medicine
Human Describe the neurovascular supply and lymphatic
inferior thoracic apertures and list the structures
Anatomy Thoracic drainage of lungs.
Re-A-003 contained/ traversing them.
Cavity Compare and contrast the anatomical features and
Describe the anatomical correlates of Thoracic outlet Integrate with
relations of right and left lung
syndrome Surgery Human
Describe the root of the lung and pulmonary ligament Anatomy
Identify and differentiate the typical from atypical ribs. Human
Anatomy with arrangement of structures at the hilum
Describe the anatomical features of ribs
Describe the anatomical correlates of supernumerary Integrate with Define Bronchopulmonary segments. Give their vascular
cervical rib. Surgery supply, lymphatic drainage and clinical significance

Classify the articulations of the ribs. Human Describe the anatomical correlates of chest tube
Re-A-014 Lungs
Re-A-004 Describe the anatomical features of these articulations. Anatomy Rib Cage intubation Integrate with
Surgery
Describe the movements with the muscles producing Human Describe the anatomical correlates of thoracentesis
articulations. Anatomy

Describe the effects of fracture to the neck of rib and Integrate with
Describe the anatomical correlates of bronchoscopy
Integrate with Pulmonology
give its anatomical justification
Orthopedics Describe the anatomical basis for medicolegal
Describe the anatomical correlates of Flail Chest. Integrate with
significance of lungs in determining the viability of Forensic
Integrate with Medicine
Describe the anatomical correlates of Thoracotomy newborn
Surgery
Re-A-005 Intercostal
Define the attachments, relations, nerve supply and Identify various anatomical landmarks on chest X-Rays, Integrate with
Human space
CT and MRI Radiology
actions of intercostal muscles Anatomy

196 198
 THEORY NORMAL FUNCTION
EMBRYOLOGY & POST-NATAL THEORY
TOTAL HOURS = 05
DEVELOPMENT
CODE
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC MEDICAL PHYSIOLOGY TOTAL HOURS = 45
CODE
Describe the development of ribs, sternum, and SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Bony
Human Enlist the muscles of inspiration and expiration in quiet
Re-A-015 thoracic vertebrae. Give the associated congenital components of
Embryology
malformations Thoracic cavity breathing Integrate with
List the embryological sources of the diaphragm. Enlist the muscles of inspiration and expiration in Anatomy
Human labored breathing
Describe the events taking place in the development
Embryology
Diaphragm & Re-P-001 Explain the components of the work of breathing Breathing
Re-A-016 and descent of the diaphragm
Thoracic cavity Medical
Describe the development of Thoracic cavities (Pleural Discuss the mechanics of pulmonary ventilation
Integrate with Physiology
and Pericardial cavities) Pediatrics Explain periodic breathing
Describe the development of upper respiratory tract: Explain the causes and pathophysiology of sleep Integrate with
Human
Embryology apnea medicine
larynx and trachea
Re-A-017 Upper
Describe congenital anomalies of Trachea- Integrate with Define and explain lung compliance
Respiratory
Tracheoesophageal fistulas of different types Pediatrics Tract Enlist the factors that affect lung compliance
List the phases of lung development with their time Draw the compliance diagram of air filled and saline Medical
Human filled lungs Physiology
periods. Describe the events taking place in each Re-P-002 Lung
Embryology
Enlist the components of surfactant Compliance
phase
Re-A-018
Describe the embryological basis of respiratory Lungs Describe the role of surfactant in lung compliance
Integrate with Integrate with
distress syndrome/Hyaline membrane disease, Ectopic
Pediatrics Explain the role of surfactant in premature babies
Pediatrics
Lung lobes, Congenital cysts of Lung
Define the different lung volumes and capacities and
THEORY
their clinical significance
MICROSCOPIC STRUCTURE TOTAL HOURS = 04 Discuss Forced Expiratory Volume 1/ Forced Vital
CODE
SPECIFIC LEARNING OUTCOMES DISCIPLINE TOPIC Capacity (FEV1/FVC) ratio and its clinical significance Medical
Physiology
Give the general histological organization of respiratory Organization of Enlist the lung volumes and capacities that cannot be
Re-A-019 Histology respiratory Lung volumes
system. Re-P-003 measured by spirometer. and
system
Define dead space & explain its types Capacities
Describe the microscopic features of respiratory Respiratory
Re-A-020 Histology
epithelium & Olfactory epithelium epithelium Discuss FEV1/FVC ratio in relation to Bronchial
Re-A-021 Describe histology of Nasopharynx Histology Nasopharynx Asthma. Integrate with
Discuss FEV1/FVC ratio in relation to Chronic Pulmonology
Describe the histological features of epiglottis and Epiglottis &
Re-A-022 Histology
larynx larynx Obstructive Pulmonary disease/restrictive lung

199 201

Trachea & diseases

Describe the histological features of trachea and lungs lungs
Re-A-023 Histology Discuss Forced Expiratory Volume 1/ Forced Vital
Describe histology of blood-air barrier blood-air
barrier Integrate with
Capacity (FEV1/FVC) ratio in relation to pulmonary
medicine
Explain the histological basis of: embolism
1. Laryngitis
Define alveolar ventilation.
2. Singer’s nodules Medical Pulmonary
Re-P-004 Define minute respiratory volume
Integrate with Clinical Physiology ventilation
Re-A-024 3. Emphysema
Pathology correlates Describe the pressures in the pulmonary system.
4. Pneumonia
Describe the blood volume of the Lungs
5. Atelectasis
Describe the distribution and regulation of blood flow
6. Infant respiratory distress syndrome
through the lungs.
Describe the mechanics of blood flow in the three
blood flow zones of the lung
Re-P-005 Describe the effect of heavy exercise on pulmonary Pulmonary
HISTOLOGY TOTAL HOURS = 05
Circulation
CODE arterial pressure.
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Describe the function of pulmonary circulation when
Identify, draw and label the histologic sections of Epiglottis&
Re-A-025 left atrial pressure rises as a result of left-sided heart Medical
epiglottis and larynx. Larynx
failure. Physiology
Trachea &
Describe the histological features of bronchial tree: Organization of Explain pulmonary capillary dynamics.
Re-A-026
trachea, bronchi, bronchioles, alveoli Respiratory Discuss pathophysiology and common causes of
System
Identify, draw and label the histological sections of pulmonary edema

bronchial tree: trachea, bronchi, bronchioles, alveoli, Explain the safety factors that prevent pulmonary
Pulmonary
Lung Re-P-006 edema. Edema, and
Histology Pleural Fluid
Describe the mucosal changes encountered in the Explain the physiological basis of the presence of fluid
Re-A-027 Bronchial tree
trachea-bronchial tree & Lung
normally in the pleural cavity.
Define pleural effusion and give its causes.
Compare and contrast the histological features of
Explain the ultrastructure of respiratory membrane
various components of bronchial tree: trachea, bronchi,
bronchioles, alveoli. Discuss the factors affecting diffusion of gases across
the respiratory membrane
Describe, compare and contrast the light and electron
Re-A-028 Pneumocytes Explain the diffusion capacity of respiratory membrane Principles of
Medical
microscopic features of type I and type II pneumocytes Re-P-007 Gaseous
for oxygen and carbon dioxide Physiology
Exchange
Define alveolar, pleural and transpulmonary pressure.
Explain differences in the partial pressures of
atmospheric, humidified, alveolar air and explain
200 202
 physiological basis of change in each pressure Describe the signs and symptoms of Pneumothorax with Surgery x

Explain the different forms of transport of oxygen in the Transport of Enlist the causes of Pleuritis
Re-P-008 oxygen in the
blood Re-P-024 Describe the signs and symptoms of Pleuritis Pleuritis
blood
Draw and explain oxyhemoglobin dissociation curve Discuss the management of Pleuritis
Enlist the factors that cause the rightward shift of Medical Enlist the causes of Bronchitis
oxyhemoglobi
oxyhemoglobin dissociation curve Physiology Re-P-025 Discuss the signs and symptoms of Bronchitis
n dissociation Bronchitis
Enlist the factors that cause the leftward shift of curve Discuss the management of Bronchitis
Re-P-009
oxyhemoglobin dissociation curve Classify different types of pneumonia

Explain the Bohr`s effect Bohr`s effect Re-P-026 Discuss the sign symptoms of pneumonia Pneumonia
Integrate with Discuss the management of pneumonia Integration
Define, enlist the types and causes of cyanosis Cyanosis with General
Medicine
Classify different types of asthma
Medicine
Enlist different forms in which Carbon dioxide CO2 is
Re-P-027 Discuss the signs and symptoms of asthma Asthma
transported in the blood
Discuss the management of asthma
Explain carboxyhemoglobin dissociation curve Medical Transport of Classify different types of Tuberculosis
Re-P-010
Physiology CO2 in blood
Explain the Haldane effect Re-P-028 Discuss the signs and symptoms of tuberculosis Tuberculosis
Explain the chloride shift/Hamburger phenomenon Discuss the management of Tuberculosis
Define the respiratory exchange ratio (RER) Classify different types of acute respiratory distress
Explain the alveolar oxygen and carbon dioxide
syndrome Acute
pressure when Pulmonary ventilation (V) and Perfusion Integration respiratory
Discuss the signs and symptoms of acute respiratory
(Q), VA/Q= infinity, zero, and normal Re-P-029 with General distress
VA/Q distress syndrome
Medical (ventilation Medicine syndrome
Re-P-011 Explain the concept of physiological shunt when VA/Q
Physiology perfusion Discuss the management of acute respiratory distress
ratio is above normal ratio) syndrome
Explain the concept of physiological dead space when
Define respiratory failure
VA/Q ratio is above normal Integration
Describe various types of respiratory failure Respiratory
Enlist the respiratory and non-respiratory functions of Re-P-030 with General
Enlist various causes of respiratory failure Failure
Medicine
the lung Medical Protective
Re-P-012 Outline management strategies of respiratory failure
Explain the nervous control of bronchiolar musculature Physiology reflexes
First Aid in
Re-P-031 Describe ABC in a trauma patient Integration
Trace the reflex arc of cough reflex and sneeze reflex Surgical
with Surgery
Patients
Explain the principle means by which acclimatization
occurs THEORY
Medical Aviation and MEDICAL BIOCHEMISTRY TOTAL HOURS = 14
Re-P-013 Explain the events that occur during acute mountain
Physiology space CODE
sickness SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Enlist the features of chronic mountain sickness Explain and interpret the pedigree of single gene Medical Genetic
Re-B-001
Biochemistry defects
203 205

Explain the pathophysiology, features, prevention and Medical Deep sea defect i.e., Emphysema and cystic fibrosis (autosomal
Re-P-014
treatment of decompression sickness. Physiology diving recessive)
Draw and explain the effect of CO poisoning on Medical Describe the biochemical basis of emphysema,
oxyhemoglobin dissociation curve Physiology Carbon Chronic obstructive pulmonary disease (COPD) and Medical
Re-P-015 monoxide Biochemistry
Explain the pathophysiology, features, and treatment of cystic fibrosis Respiratory
Integrate with poisoning Re-B-002
diseases
CO poisoning. Medicine Interpret Respiratory Distress syndrome on the Integrate with
Enumerate the components of respiratory centers and basis of given data Physiology

explain their functions. Discuss the concept of acid base balance

Medical Nervous
Re-P-016 Explain the inspiratory RAMP signal regulation of
Physiology Interpret metabolic and respiratory disorders of Medical
Explain the Herring Breuer reflex/lung inflation reflex respiration
Biochemistry
acid base balance on the basis of sign, symptoms and Acid base
and its clinical significance Re-B-003
ABG findings balance
Explain the location of chemo sensitive area (central
Describe the Clinical interpretation of acid base Integrate with
chemoreceptors) and peripheral chemoreceptors
balance Medicine
Explain the effect of hydrogen ions & carbon dioxide on Medical Chemical
Re-P-017 control of
the chemo- sensitive area Physiology
respiration
Explain the role of oxygen in the control of
respiration/peripheral chemoreceptors TOTAL HOURS = 10
CODE SPECIFIC LEARNING OBJECTIVES
DISCIPLINE TOPIC
Re-P-018 Explain the regulation of Respiration during Exercise Medical Exercise and
Physiology Respiration Perform the clinical examination of chest for the Clinical
Re-P-039 respiratory system (inspection, palpation, percussion, Examination
Auscultation) of Chest
Enlist the effects of acute hypoxia
Peak
Explain the hypoxia inducible factor a master switch for Medical
Expiratory
Physiology Re-P-040 Determine lung volumes and capacities with spirometer
Re-P-019 body response to hypoxia Hypoxia Flow rate
measurement
Integrate with Medical
Define and explain different types of hypoxias Physiology
Medicine
Determine Blood Oxygen Saturation with finger Pulse Oxygen
Re-P-041
Re-P-020 Explain the pathophysiology of Tuberculosis. Integrate with Oximeter Saturation
Tuberculosis
Pathology
Re-P-021 Describe the pathophysiology of Pneumonia Integrate with
Pneumonia
Pathology
Perform Cardio pulmonary Resuscitation (CPR) on
Define Dyspnea Re-P-044 CPR
adult and infant.
Enlist different causes of dyspnea General
Re-P-022 Dyspnea
Differentiate between cardiac and respiratory dyspnea Medicine
Determine the pH of the solution by pH meter Medical Determination
Re-B-005
Outline management strategies for dyspnea Biochemistry of pH
Re-P-023 Enlist the causes of Pneumothorax Integration Pneumothora
204 206
 PATHOPHYSIOLOGY AND PHARMACOTHERAPEUTICS

THEORY
TOTAL HOURS = 5+3=08
CODE SPECIFIC LEARNING OBJECTIVES
DISCIPLINE TOPIC
Identify the drugs for cough suppression &
expectoration Cough
Re-Ph-001
Explain the mechanism of action and adverse effects Suppressants
of cough suppressants Pharmacology
&
Explain the mechanism of action and adverse effects Therapeutics
Re-Ph-002 Antihistamines
of anti-histamines
Explain the mechanism of action and adverse effects
Re-Ph-003 Anti asthmatics
of anti-asthmatics
Acute
Describe the pathophysiology of acute respiratory Respiratory
Re-Pa-001
distress syndrome Distress
Syndrome
Describe the pathophysiology of obstructive lung Obstructive lung
Re-Pa-002 Pathology
disease Disease

Describe the pathophysiology of Restrictive Lung Restrictive

Re-Pa-003
Disease Lung Disease

DISEASE PREVENTION & IMPACT

THEORY
TOTAL HOURS = 10
CODE SPECIFIC LEARNING OBJECTIVES
DISCIPLINE TOPIC
Identify the common risk factors of acute respiratory
infections with emphasis on smoking
Community Prevention of
Discuss preventive strategies of different problems Medicine and
Re-CM- acute
related to respiratory system Public Health Respiratory
001
Enlist the common vaccines used for the prevention of Infections
(ARI)
ARI
Explain the role of vitamins in the respiratory tract Integrate with

207

infections Biochemistry
Interaction of
Explain the effect of air pollutants on the respiratory environment
Re-CM-002
system & Respiratory
System

Epidemiology of
Re-CM-003 Describe the burden of respiratory diseases Community respiratory
Medicine and Diseases
Public Health

Enlist the common respiratory diseases related to Occupational

Re-CM-004 Lung
occupation
Diseases

Re-BhS-001 identify the psychosocial factors leading to dyspnea. Dyspnea

Identify the psychosocial factors leading to Psychogenic

Re-BhS-002
psychogenic cough. Cough
Behavioral
Identify and deal with the various psychosocial aspects
Sciences Personal,
of Respiratory conditions (such as Asthma, COPD, Psychosocial
Re-BhS-003
Tuberculosis, Cystic Fibrosis, Sleep Apnea) on and vocational
issues
Individual, Family and Society.

AGING

THEORY
TOTAL HOURS = 03
CODE SPECIFIC LEARNING OBJECTIVES
DISCIPLINE TOPIC

Discuss the biochemical basis of respiratory infections Respiratory

Re-Ag-001 infections in old
in old age in cold weather
age
Discuss the role of age on respiratory clearance Increased
leading to recurrent inflammatory processes at the vulnerability to
Pathology
infection &
Re-Ag-002 ciliated respiratory epithelium neoplasia
Describe the biochemical basis of emphysema, COPD Respiratory
and cystic fibrosis diseases

208