1. Alongside some paraneoplastic syndromes, the tumors that 11. What is the karyotype like in Noonan syndrome?

are most often responsible for them are indicated. Indicate 46 XY

which combination is wrong.
Hypoglycemia - Ovarian cancer 12. How does insulin affect the activity of lipoprotein lipase in
adipose tissue?
2. With which cellular structure is adenylate cyclase associated? It stimulates it.
Plasma membrane
13. By which mechanisms is respiratory deficit determined in
3. It acts mainly on the protein matrix of the bone: great obesity?
Cortisol For all the mechanisms mentioned.

4. Adrenergic hormone analogues are used as pharmacological 14. With reference to Cushing's paraneoplastic syndrome, all of
agents: the following propositions are correct except one. Indicate
In all the above which.
The tumor secretes cortisol.
5. Azoospermia means:
Absence of sperm in the ejaculate 15. What is used in the therapy of De Quervain's thyroiditis?
Corticosteroids.
6. What is colloid?
It is the storage form of thyroglobulin in the lumen of the 16. What are bisphosphonates?
thyroid follicle. They are analogues of inorganic pyrophosphate in which the
oxygen atom is replaced by a carbon atom.
7. What is meant by endocrine secretion?
It is the secretion of hormones that act at a distance. 17. What are SERMs?
They are a new class of drugs that are able to modulate
8. What is meant by paracrine secretion? estrogen receptors.
It is the secretion of hormones that act on nearby cells.
18. What is metformin and how does it work?
9. What effect does testosterone have on bone resorption and It is a biguanide, whose anorectic power is exploited.
mineralization?
It decreases bone resorption and stimulates mineralization. 19. From which type of endocrine pancreas cells is insulin
secreted?
10. Circulates widely bound to carrier proteins: Beta cells.
Testosterone
20. From the histopathological point of view, what is the 30. What is the most useful instrumental test to identify areas of
characteristic of the endocrine glands site of autoimmune functional autonomy during thyrotoxicosis in a patient
pathology? affecting multinodular goiter?
Lymphocytic infiltration. Thyroid scintigraphy.

21. Which anabolic androgenic steroids are permitted for use in 31. What is the expression that allows you to calculate the "Body
sports activity? Mass Index" (BMI)?
None, without distinction. Body weight in kg/square of height in meters.

22. Is insulin an antagonist? 32. What is the immediate precursor steroid of cortisol?
No, it is not. 11-desoxycortisol.

23. What causes hyperprolactinemia? 33. What is the "counter-regulatory" hormone that causes
Therapy with haloperidol. hyperglycemia?
Cortisol.
24. What is considered a TSH-dependent thyroid carcinoma?
Follicular. 34. What is produced by cytotrophoblast?
HCG (Human Chorionic Gonadotropin).
25. What is the mechanism of action of the "classic" receptors for
steroid hormones? 35. What is produced by the oophorus follicle?
They modulate the transcription of genes. Inhibin.

26. What is the main inhibitory control factor of prolactin release? 36. What is a metabolic effect of GH?
Dopamine. It stimulates lipolysis.

27. What is the most frequent cause of hypoparathyroidism? 37. What is a test that allows the diagnosis of diabetes mellitus in
Post-surgical. doubt cases?
Oral glucose tolerance test (OGTT).
28. What is the most frequent thyroid disease?
Simple goiter. 38. What is a drug that does not cause hyperprolactinemia?
Propranolol.
29. What is the most frequent heart rhythm alteration in case of
toxic thyroid adenoma? 39. What is a hypothalamic factor that physiologically stimulates
Atrial fibrillation. the secretion of prolactin?
MARKET (prolactin-releasing peptide).
40. What is a marker to assess the trend of differentiated thyroid 50. What is a malignant thyroid neoplasity that presents a rapidly
carcinoma after total thyroidectomy? invasive progress?
Thyroglobulin. Carcinoma anaplastico.

41. What is a hormone that has structural analogies with TSH? 51. What is a pathology characterized by the presence of
LH (Luteinizing Hormone). autoantibodies directed against the TSH receptor?
Graves' disease.
42. What is a hormone that has an amino acid as a precursor?
Norepinephrine. 52. What is an endocrinopathy that can cause
hyperprolactinemia?
43. What is a hormone that has intracellular receptors? Primary hypothyroidism.
Thyroxine.
53. Is there statistically a direct relationship between an increase
44. What is a hormone that responds to stress? in body weight and an increase in blood pressure levels?
PRL (Prolactin). Yes, and it is significant in major epidemiological studies.

45. What is a hormone made up of subunits? 54. What is part of the typical picture of MEN 2A?
HCG (Human Chorionic Gonadotropin). Medullary thyroid carcinoma.

46. What is a hormone whose secretion is stimulated by arginine? 55. Promotes statural growth:
GH (Growth Hormone). Testosterone.

47. What is a contraindication to radioiodine therapy in subjects 56. Among the ovarian estrogens, which is most active?
with hyperthyroidism? Estradiol.
Pregnancy.
57. GnRH analogues:
48. What is a form of dysfunctional hypothalamic anovulatory All of the above.
amenorrhea?
Amenorrhea in female athletes. 58. The pituitary hormones are:
Glycopeptides and polypeptides.
49. What is an endocrine disease caused by an adrenal adenoma
that secretes glucocorticoids? 59. Polypeptide hormones bind to receptors:
Cushing's syndrome. Of membrane.
60. Steroid hormones act on the target cell: 70. The mature secretion granules released from the pancreas
Entering cells by diffusion and interacting with cytoplasmic contain:
receptors. Insulin and C-peptide in equimolar concentrations and small
quantities of proinsulin
61. Steroid hormones are characterized by:
Being rapidly synthesized from precursors and secreted into 71. Angiotensin II receptors are located:
the bloodstream. On cell membranes

62. Steroid hormones are derivatives of: 72. The symptoms of primary hyperaldosteronism are:
Cholesterol. All of the above

63. Thyroid hormones derive from the metabolism of: 73. PR values vary with:
Tyrosine All of the above

64. Thyroid hormones exert a negative feedback action at the 74. Normal blood sodium levels are:
level of: 135-145 mEq/l
Anterior pituitary and hypothalamus
75. The karyotype of typical Turner's syndrome is:
65. Sperm are produced in: XO
Seminiferous tubules
76. The catabolism and elimination of catecholamines occur
66. Has a stimulatory effect on GH secretion: mainly through:
All of the above Deamination/decarboxylation

67. Chylomicrons are the lipoproteins: 77. Protein catabolism is promoted by:
Lower density Cortisol

68. Cytochromes P450 are involved in the synthesis: 78. Cyproterone acetate, used in prostate therapy, determines:
Of steroid hormones Inhibition of androgen biosynthesis at the adrenal level

69. Glucocorticoids have an effect: 79. Cyproterone is a:

All of the above Progestin

80. Cortisol acts on metabolism:

Of all the above
81. The circulating cortisol is carried by: 90. The major effect of an intermediate-acting insulin
Transcortin administered subcutaneously is obtained after:
6-8 hours

82. The deficit of which gland can cause infantile 91. The negative feedback mechanism of cortisol is exerted on:
hypostaturealism: CRH and ACTH
Thyroid
92. The most common mechanism through which a drug causes
83. Central diabetes insipidus is caused by: hyperprolactinemia is:
ADH deficiency Blockade of dopamine receptors

84. Fasting causes hyperuricemia due to: 93. The active metabolite of vitamin D (1-25,OH-D3) is formed at
a+b the level of:
Rene
85. Pheochromocytoma is:
A chromaffin cell tumor 94. The best diagnostic test for Addison's disease is:
Test all'ACTH
86. In 90% of cases, pheochromocytoma causes:
In the adrenal medulla 95. Addison's disease, Flajani-Basedow's disease, and some forms
of insulin-dependent diabetes all have an etiopathogenesis of
87. The mature follicle, in the pre-dehiscence phase, has a the following type:
diameter of approximately: Autoimmune disease
20 mm
96. The chemical name of melatonin is:
88. The correct functioning of the female reproductive system N-acetyl-5-methossitryptamine
depends on the interaction of various hormones. Besides
those coming from the pituitary, from which other gland 97. Peptide C:
and/or organ: It is a fragment of the original molecule from which insulin is
Ovary formed

89. Glucagon and catecholamines stimulate glycogenolysis at the

level: 98. The ovulatory LH peak:
Hepatic It precedes ovulation.
99. The most common visual defect in patients with pituitary
adenoma is represented by: 109. TRH stimulates the secretion of:
Temporal hemianopia. TSH e PRL.

100. The most powerful stimulus for insulin secretion is: 110. In case of concomitant secondary hypothyroidism and
Glucagon. hypoadrenalism, replacement therapy with thiorhone
hormones:
101. The initial precursor for the synthesis of ovarian It should be started after glucocorticoid therapy.
hormones is represented by:
LDL cholesterol. 111. In case of antiandrogen therapy in a woman of fertile
age:
102. PTH is increased or at the limits of normal in all these Contraceptive coverage is required.
conditions except one; which?
Hypercalcemia associated with neoplasms. 112. What does the Wolff-Chaikoff effect consist of?
In the inhibition of iodination of thyroglobulin induced by
103. The ratio of insulin molecules/secreted C-peptide large doses of iodine.
molecules is:
1:1. 113. How do hormones interacting with nuclear receptors
differ from those interacting with membrane receptors?
104. The insulin receptor is: Absence of interaction with second messenger.
A tyrosine kinase.
114. During pregnancy, pharmacological therapy for
105. The single most useful hormone measure for the diabetes includes:
diagnosis of Cushing's syndrome is: Insulin.
Urinary cortisol/24 h.
115. In the presence of a PRL value of 220 ng/mL, the most
106. Bioavailable testosterone is made up of: probable diagnosis is:
The albumin-bound fraction and the free fraction. Prolactinoma.

107. Testosterone exercises a negative feedback effect on: 116. In which phase of the menstrual cycle is the mitotic
LH. activity of the breast greater?
In the luteal phase.
108. The treatment of primary hyperaldosteronism
includes: 117. What percentage are carbohydrates, proteins, and
All of the above. lipids present in a balanced diet?
Carbohydrates = 50-60%, proteins = 20%, lipids = 20-30%.
118. In a male affected by Kallmann syndrome, the 128. The biosynthesis of steroid hormones begins with:
following hormonal values are most frequently found: Cholesterol.
Reduced LH, reduced FSH, reduced testosterone.
129. Calcification of the pineal gland is a not rare finding;
119. Hypertension is not present in one of the following because of this, the production of melatonin results:
conditions: Not modified.
Hyperaldosteronism secondary to hypovolemia.
130. The most frequent cause of congenital hypothyroidism
120. In a woman, galactorrhea can generally be caused by: is:
Hypothyroidism and hyperprolactinemia. Agenesis or thyroid dysgenesis.

121. Indicate the time period relating to a circadian rhythm: 131. The most frequent cause of thyrotoxicosis in
24 hours. pregnancy is:
M. of Basedow.
122. Indicate the most frequent type of pituitary adenoma:
PRL-secreting. 132. Cholestasis is accompanied with an increase in:
Cholesterol.
123. Indicate which of the following receptors have an
autophosphorylation domain: 133. The most frequent complication of diffuse toxic goiter
Receptors for growth factors and insulin. is:
Heart failure.
124. Inhibits the synthesis of TSH:
Somatostatin. 134. The protein component of lipoproteins is made up of:
From glycoproteins.
125. 80% of patients with hyperparathyroidism:
It shows no clinical signs and symptoms of disease. 135. The normal sperm concentration is:
Greater than 20,000,000/ml.
126. The "glucotoxicity" associated with chronic exposure
to hyperglycemia causes: 136. The certainty diagnosis of gouty arthritis is made
Decreased pancreatic response to secretory stimuli. through:
Arthrocentesis.
127. 5-alpha-reductase is an enzyme that catalyzes the
transformation of: 137. The most likely diagnosis in a patient with a unilateral,
Testosterone to dihydrotestosterone. hypertensive, hypotaxemic, and hirsute adrenal mass is:
Adrenal carcinoma.
 148. The presence of visceral (or intra-abdominal) obesity is
138. The frequency of type 1 diabetes mellitus in the frequently associated with:
general population is: Low HDL, small and dense LDL, high TG.
0.3-0.5%.
149. The main electrolytic alteration present in Addison's
139. The metabolic function most activated by insulin is: disease is:
Postpones. Hyponatremia.

140. Leptin: 150. The main action of the FSH hormone in humans is on:
It is a hormone produced by adipose tissue that inhibits Seminiferous tubules.
appetite.
151. Insulin production:
141. The most frequent manifestation of hyperthyroidism in It is equimolar with respect to that of C-peptide.
the elderly is:
Atrial fibrillation. 152. Prostatectomy is associated with:
Retrograde ejaculation.
142. Melatonin is a hormone:
Indolic. 153. The reduced biological activity of insulin in obesity is
secondary to:
143. Melatonin has a circadian rhythm synchronized by the Receptor and/or post-receptor defect.
alternation of:
Dark/light.
154. The reduction of androgens after desametazone
144. Diabetic autonomic neuropathy may affect: affects:
All of the above. Congenital adrenogenital syndrome.

145. The pineal is anatomically located: 155. The secretion of cortisol in the normal subject is:
Between the superior colliculi. Circadian with phasic increases in case of stress.

146. The most frequent pineal neoplasia is: 156. The secretion of cortisol in the normal subject:
Germinoma. It generates a negative feedback loop at the level of the
pituitary gland.
147. Does the presence of obesity double the risk of
ischemic heart disease? 157. GH secretion is controlled by:
True, both in men and women. GHRH and somatostatin system.
158. Aldosterone secretion is increased by: FSH.
All of the above.
170. The basic structure of steroid hormones can be traced
159. Aldosterone secretion may be increased by: back to:
All the aforementioned eventualities. Cyclopentaneperhydrophenanthrene.

160. The secretion of cortisol is of the type: 171. The treatment of male primary hypogonadism
Circadian. normally involves the use of:
Testosterone.
161. Prolactin secretion is stimulated by:
MARKET. 172. Vasopressin is also called:
An adiuretic.
162. Adrenogenital syndrome is due to:
Enzyme defects of the adrenal gland. 173. The abuse of anabolic steroids in sports practice
determines:
163. Kallmann syndrome is characterized by: Increase in strength and muscle mass.
Hypogonadotropic hypogonadism associated with anosmia.
174. The acronym APUD stands for cells:
164. Laron syndrome is: Capable of incorporating and decarboxylating the precursors
A hormone resistance syndrome. of biogenic amines.

165. Sheehan's syndrome is hypopituitarism due to: 175. Adenylcyclase is:

Postpartum necrosis of the pituitary gland. Membrane enzyme.

166. The synthesis of which hormone is controlled by 176. Adrenaline:

somatostatin? Causes bronchodilation.
Growth hormone.
177. Adrenarche coincides with an increase in plasma levels
167. The synthesis and excretion of corticotropin is of:
controlled by: GOOD.
Cortisol.
178. Angiotensin is a polypeptide necessary for the
168. Somatostatin controls DI synthesis: synthesis of:
Growth hormone. Aldosterone.

169. Spermatogenesis is regulated by: 179. Angiotensinogen is produced by:

 Liver. 190. Physical exercise:
Stimulates GH secretion.
180. The increase in plasma glucose concentration causes
an increase in the synthesis of: 191. The most frequent outcome of Hashimoto's thyroiditis
Insulin. is:
Hypothyroidism.
181. The increase of progesterone in the luteal phase of the
cycle indicates: 192. Exophthalmos is a clinical sign characteristic of:
Ovulation occurred. Basedow's disease.

182. The action of PTH on the synthesis of vitamin 193. The most frequent etiology of adrenal insufficiency is:
1,25(OH)2D3 explains at the level: Autoimmune.
Part clean.
194. Early heart heart in young people occurs more easily in
183. Catecholamines promote: the course of:
Glycogenolysis. Familial hypercholesterolemia.

184. Sertoli cells are found: 195. Inhibin B:

In the seminiferous tubule. It inhibits FSH.

185. The physiological ways of regulation of the activity of 196. Inhibin is product of:
an enzyme include: Sertoli cells.
All of the above.
197. Inhibin exercises feed-back:
186. Ion exchange resins act: Negative FSH.
By inhibiting the enterohepatic circulation of bile acids.
198. Insulin stimulates:
187. The main effect of cortisol is to promote: Glycogen synthesis.
Neoglucogenesis.
199. Insulin:
188. Electrophoresis separates serum lipoproteins: Stimulates glycogen synthesis and lipogenesis.
Based on the electric charge.
200. Insulinoma is responsible for:
189. The enzyme that converts proinsulin into insulin is: Spontaneous hypoglycemia.
Carboxypeptidase H.
201. The orchiopessi surgery must be carried out:
 Between 2 and 4 years of age and in any case before the start 211. The most powerful physiological stimulus than atrial
of pubertal development. natriuretic hormone secretion is:
The expansion of the body's sodium pool.
202. Primary hyperaldosteronism is characterized by:
Hypokalemia. 212. Obesity causes a greater risk of diabetes for the
following reason:
203. Hyperlipidemia secondary to type II diabetes presents Insulin resistance.
with:
Hypertriglyceridemia. 213. The antidiuretic hormone works at the level of:
Distal tubule.
204. Primary hyperparathyroidism and tumor
paraneoplastic hypercalcemia have several similar biochemical 214. Growth hormone regulates the synthesis of:
aspects. Which of the following data might raise Somatomedina.
paraneoplastic syndrome?
Blood Cl-/phosphate ratio <35. 215. The somatotroph hormone acts on the metabolism of:
All of the above.
205. Hyperthyroidism promotes:
Hepatic elimination of cholesterol. 216. Oxytocin is a hormone:
Peptidico.
206. Postprandial hypoglycemia in obese is due to:
Hyperinsulinemia. 217. The use of estroprogestines:
It is a predisposing factor to hypertriglyceridemia.
207. Hypokalemia can be found in all of the following
events except: 218. Marker of the adrenogenital syndrome (Congenital
In Addison's disease. adrenal hyperplasia) due to 21-hydroxylase deficiency is the
elevation of:
208. The most frequent histotype of pituitary adenoma is: 17-OH-progesterone.
PRL-secreting adenoma.
219. In patients affected by Laron's dwarfism, the serum GH
209. Pseudohypoparathyroidism is due to: and IGF - I values are:
Parathyroid hormone receptor defect. Elevated GH, reduced IGF-I.

210. The functional status of the adrenal gland is best 220. In genetically predisposed subjects, for the equal
investigated with: number of calories introduced, which of the following
Combined measurement of urinary cortisol and ACTH. combinations exercises the greatest diabetogenic role?
 Hyperlipidic diet, rich in carbohydrates, low in proteins and
low in fiber. 229. In normal women, the highest plasma levels of
gonadotropins have:
221. In males, the first sign of puberal development is in In menopause.
most cases:
Increase in testicular volume. 230. In girls, the first sign of puberal development is in most
cases:
Onset of breast development.
222. In Addison's disease, it is possible to find:
Hyperkalemia. 231. In menopause, it is high:
FSH.
223. In Addison's disease, there is:
Melanoderma. 232. In Morris syndrome, testosterone levels are:
Normal for a male adult.
224. In Basedow's disease, thyroid hyperfunction is due to:
Thyroid-stimulating immunoglobulins. 233. In Sertoli cell-only syndrome or germinal aplasia, the
following are normally found:
225. In the patient with Addison's disease, in case of Normal LH, elevated FSH, normal testosterone, reduced
hyperpyresia, glycemic therapy is: inhibin.
Doubled.
234. In Conn's syndrome therapy is indicated with:
226. In the patient with suspected hypoglycemia, the Spironolactone.
reversibility of the symptoms that is reported after ingestion
of sugar: 235. In Cushing's syndrome due to adrenal neoplasia, ACTH
It's not dire. secretion:
Has decreased.
227. In the obese patient with non-insulin-dependent
diabetes, does insulin treatment induce a further increase in 236. In typical Klinefelter's syndrome high values of:
body weight? FSH.
This is true only within the first year of therapy, while the
weight tends to stabilize thereafter. 237. In chronic kidney failure, the finding is frequent:
Of hypertriglyceridemia.
228. In the diet of a diabetic individual, an acceptable
percentage distribution of carbohydrates, proteins, and fats 238. In primary hyperaldosteronism, they are found:
can be, respectively: Increased aldosterone and decreased renin.
50-20-30.
239. In primitive hyperaldosteronism, the maintenance of
hypertension is due to: 248. May be present during thyrotoxic crisis:
Increase in peripheral resistance. Hyperthermia.

240. In chronic hypocorticoadrenalism, therapy is indicated 249. May play a role in the ethiopathogenesis of type 1
with: diabetes:
Hydrocortisone. A previous viral infection.

241. In hypoparathyroidism, the following are generally 250. What is the biological precursor of insulin?
found: Proinsulin.
Hypocalcemia, hyperphosphatemia, hypocalciuria,
hypophosphaturia. 251. What is the physiological concentration of fasting
plasma glucose (mg%)?
242. In post-menopause osteoporosis, the calcium load is: 70-110.
Normal.
252. What is the most common pathological alteration of
243. For which of the following forms of thyroid carcinoma hyperaldosteronism?
has genetic transmission been documented? Adenoma.
Medullary.
253. What is the objective to achieve in the treatment of
244. By paraneoplastic endocrine syndrome means: high levels of LDL cholesterol for primary prevention?
An endocrine syndrome caused by the production of 130 mg/dl.
hormones or hormone-like substances by a nonendocrine
tumor. 254. Which clinical complication is most frequent in family
hypercholesterolemia?
245. To establish the primitive or secondary character of Ischemic heart disease.
hyperaldosteronism, it is necessary to use the dosage of:
Renin-plasma activity. 255.
Which of the following effects is not caused by cortisonic
246. Allows the diagnosis of follicular carcinoma of the therapy:
thyroid: Hyperkalemia.
None of the above.
256. Which of the following factors can increase HDL?
247. It may cause diabetes by antagonizing the effects of Estrogens.
insulin:
Pheochromocytoma.
257. Which of the following factors is associated with a
greater prevalence of ischemic heart disease in obese 265. Which of the following respiratory alterations is most
patients? frequently associated in the obese patient who does not have
All of the above. episodes of apnea during sleep?
Restrictive deficit.
258. Which of the following mechanisms are hypothesized
for the association between insulin resistance and 266. Which of the following conditions is the most frequent
hypertension in the obese patient? cause of male osteoporosis?
All of the above. Hypogonadism.

267. Which of the following anthropometric methods is

259. Which of the following parameters is most commonly currently recommended for the assessment of body fat
used in clinical practice to diagnose obesity in an adult? distribution?
Body Mass Index (BMI). Waist-hip ratio (WHR).

260. Which of the following signs/symptoms could be 268. Which of the following proteins has quaternary
present in a patient with cancer of the pineal region? structure?
All those mentioned. Hemoglobin.

261. Which of the following symptoms consist the diagnosis 269. Which of the following substances does not affect the
of primitive hyperaldosteronism? secretion of prolactin?
None of the above. ACTH.

262. Which of the following symptoms occurs most often in 270. Which of the below-listed paraneoplastic syndromes is
post-menopausal women: most often associated with lung microcytoma?
Hot flashes and night sweats. Syndrome of inappropriate ADH secretion.

263. Which of the tumors listed below is among those that 271. Which of these pathologies is most frequently
are most often responsible for Cushing's syndrome due to associated with erectile dysfunction?
ectopic ACTH? Diabetes.
Small cell lung cancer.
272. Which of these proteins is considered a protein of the
264. Which of the tumors listed below is among those that acute phase of critical diseases and consequently increases
most often can cause a picture of acromegaly due to ectopic their synthesis?
secretion of GHRH? C-reactive protein.
Bronchial carcinoid.
273. Which of these amino acids can be defined as non- 282. What is the most frequent complication that patients
essential? with PCOS encounter?
Arginine. Glucose intolerance and/or frank diabetes.

274. Which of these circulating autoantibodies is specific for 283. What is the 20-year survival for papillary carcinoma?
type 1 diabetes? 95%.
A+B.
284. Which endocrinopathy is most frequently
275. Which of these tests is essential to make the diagnosis accompanied by hypercholesterolemia?
of primitive hyperparathyroidism? Hypothyroidism.
Calcium.
285. Which of these pathologies can damage the pancreas
276. Which of these hormones is used in therapy in to the end of inducing insulin-dependent diabetes?
hypogonadotropic hypogonadism? Hemochromatosis.
HCG.
286. Which of these replacement therapies is not necessary
277. Which of these progestins also has an antiandrogenic in hypopituitarism?
action? Mineralocorticoid.
Cypoterone acetate.
287. Which of these is a symptom or signs of anorexia
278. What diagnosis can be made through the dosage of nervosa?
calcitonin? Amenorrhea.
Medullary carcinoma.
288. Which of these macronutrients has the greatest caloric
279. Which electrolytic disorder characterizes primary power?
Addison's disease? Lipids.
Hyperkalemia and hyponatremia.
289. Which of these clinical signs is missing in secondary
280. What is the main stimulus for the production of hypoadrenalism?
erythropoietin? Skin hyperpigmentation.
Hypoxia.
290. What function does oxytocin explore?
281. What is the substrate of phosphodiesterase? It favors the last stages of childbirth and lactation.
Nucleotides.
291. What is the most used drug in the induction of
ovulation in women with PCOS?
 Clomiphene citrate.
301. Which therapy is now available for homozygous
292. What is the threshold value of fasting plasma glucose familial hypercholesterolemia?
with which the diagnosis of diabetes mellitus is made? LDL-apheresis.
126 mg/dl.
302. Which infusion therapy is indicated in parathyreopriv
293. What is the most frequent complication of radiation tetanic crisis?
therapy for a pituitary adenoma? Calcium.
Hypopituitarism.

303. Which of the hormones listed below is produced by

294. What is the most frequent pathology associated with the neurohypophysis?
POF (Premature Ovarian Failure)? Vasopressin.
Turner syndrome.
304. Which of the following is the type of surgical treatment
295. What is the first cause of female infertility in the for obesity that does not require amputations and is both
Western world? anatomically and functionally reversible?
PCOS. Adjustable gastric banding.

296. What is the most frequent thyroid alteration during 305. Which FSH value is conventionally considered
interferon therapy? pathognomonic of POF (Premature Ovarian Failure)?
Hypothyroidism. 40 IU/l.

297. What is the incidence of acromegaly? 306. Which of the following drugs is able to reduce
3-4 cases per million inhabitants. testosterone levels in women with PCOS?
Metformin.
298. Which lipoprotein has the highest triglyceride content?
VLDL. 307. Which of these analyzes should be carried out in
monitoring androgen replacement therapy?
299. Which pituitary hormone stimulates the interstitial All previous.
cells of the testicle?
LH. 308. Which of these cells are contained in the seminiferous
tubules?
300. What percentage of the body mass is made up of A+B.
adipose tissue in normal-weight women?
20-30%.
309. Which of these substances affects endogenous GH Parathyroid adenoma, gastrointestinal endocrine neoplasm,
secretion? pituitary adenoma
Arginine.
318. What are the possible complications of adjustable
310. Which of these factors does not affect blood gastric banding (BGR)?
hypertension? Vomiting, dilation of the gastric pouch above the band
Sweating. (requiring repositioning or removal of the band), erosion of
the gastric wall
311. Which of these risks or side effects can occur with
taking GH? 319. What are the main sites of insulin resistance?
All previous. Mainly the muscle and the liver, while the adipose tissue plays
a minor role in the onset of the state of insulin resistance
312. Which tests are fundamental to diagnose an androgen-
secreting neoplasia in a woman with hirsutism? 320. What are the hormones of the neurohypophysis in
Testosterone and DHEAS. humans?
Antidiuretic hormone (ADH) or argininevasopressin and
313. Which hormones stimulate lipolysis? oxytocin
All of the above
321. When HCG in the urine reaches the highest values:
314. What are the hormone factors that influence basal At the 10th / 12th week
metabolism?
Thyroid hormones and catecholamines 322. When an individual loses weight:
The volume is reduced, but not the number of adipocytes
315. What are the main side effects of insulin in a healthy
subject?
A+B 323. You have hypoglycemia in:
Reticuloendothelial tumor that secretes IGF II
316. What are the most frequent alterations in the lipid
status in patients with central obesity? 324. It is used in therapy to prevent osteoporosis:
Plasma concentrations of free fatty acids, triglycerides, and None of the above
small, dense LDL lipoproteins are increased, while plasma
concentrations of HDL cholesterol are reduced. 325. When a patient is defined as hirsute:
When it has hair growth in areas typical of the male sex
317. What are the neoplasies that distinguish the clinical
picture of MEN1?
326. Both endogenous and exogenous melatonin 335. A very rare picture of paraneoplastic hyperthyroidism
demonstrate actions on sleep; among them, the most may be caused by one of the tumors listed below. Indicate
documented is: which:
All of the above Choriocarcinoma

327. It looks like the structure of cholesterol: 336. An infradian rhythm is a rhythm with a period greater
Vitamin D than 24 hours

328. Structurally looks like insulin: 337. A subject with diuresis of 3-4 L/D and specific gravity of
Somatomedina 1024 may more likely have:
Diabetes mellitus

329. Among the various pituitary adenomas, the

prolactinoma has a frequency of:
40-50%
338. A 47-year-old man has been complaining of deep
330. An increase in urinary albumin excretion is often asthenia for a few weeks. The remote pathological history is
associated with: negative. Objective examination reveals no significant data.
Long-term diabetes mellitus Laboratory tests show: calcium 14.1 mg/dL, phosphate 2.1
mg/dL, K 4.2 mmol/L, Na 138 mmol/L, unstable PTH. Which of
331. Among the various sites of the urogenital system those listed below is the most likely cause of hypercalcemia?
which may present cancer, obese man is at greater risk of: Neoplasia
Prostate cancer
339. A general characteristic of tumors that can cause
332. Among the neoplasies of the thyroid, the most paraneoplastic syndromes is that of processing:
frequent histotype is: Peptide hormones

333. A "fruity" breath is appreciated in the course of: 340. One of these laboratory conditions is compatible with
Diabetic ketoacidosis secondary hypothyroidism:
Papillary carcinoma Low FT4 and normal or low TSH

334. Primitive damage to the seminiferous tubules causes: 341. A 45-year-old woman complains of asthenia and
Increased FSH muscle weakness. She also reports intermittent episodes of
headache. The objective examination is negative except for a
pressure of 155/105. Laboratory tests show no alterations
except for the serum electrolytes which have the following
 values: sodium 152 mmol/L, potassium 2.5 mmol/L, chlorine 348. A substance is defined as a hormone when it has the
110 mmol/L, and carbon dioxide of 37 mmol/L. The patient is characteristics of being:
not taking drugs. Plasma renin levels do not increase in Synthesized and transported in circulation and determines
orthostatism. The most appropriate subsequent test is: "effects" on target cells
Plasma aldosterone measurement after intravenous infusion
of saline solution 349. Values higher than the FSH standard are characteristic
of:
342. A 16-year-old girl in good health presents with primary Primary testicular damage
amenorrhea. On physical examination: female external
genitalia with scant pubic and axillary hair, FSH 9.3 mU/ml, LH 350. It is produced by the corpus luteum:
30.5 mU/ml, T 8.9 ng/ml, DHT 57 ng/dl, PRL 6 ng /ml, E2 50 Progesterone
pg/ml; karyotype: 46, XY. Pelvic ultrasound: absence of the
uterus and appendages. CT scan: undescended testes in the
abdominal area. The diagnosis is:
S. of Morris

343. A glucose measure of 160 mg/dL 2 hours after an oral

glucose load suggests:
Impaired carbohydrate tolerance

344. A glucose measure of 220 mg/dL 2 hours after an oral

glucose load suggests:
Diabetes mellitus

345. A normal measure polarity excludes a diagnosis of

hyperaldosteronism:
No, if the patient follows a low-sodium diet

346. An autocrine secretion is:

A secretion that acts on the production cells themselves
through the interstitium

347. A suppression of TSH with normal thyroid hormone

values is compatible with:
Subclinical hyperthyroidism