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ALP: Adaptive Lossless Floating-Point Compression

C++ 225 17 Updated Oct 16, 2025

Next-Gen Big Data File Format

C++ 698 39 Updated Apr 22, 2026

A new block-compression format based on Zstd

Rust 5 1 Updated Jul 16, 2026

AI agent sandboxing done right.

Go 183 8 Updated Aug 5, 2026

the runtime your coding agents live on

Rust 24,636 1,727 Updated Aug 5, 2026

Blazingly fast, streaming duplicate detection for NGS data

Rust 17 Updated Aug 1, 2026

An extensible and performant aligner and read mapper

Rust 99 3 Updated Jul 27, 2026

Successor of bwa-mem for short-read alignment

C 317 18 Updated Aug 4, 2026

A GNU screen style terminal multiplexer built on libghostty.

Zig 751 23 Updated Jul 5, 2026

TermLoop workspace

Swift 36 1 Updated Aug 5, 2026

A unified interface for AI in your terminal.

Python 3,357 154 Updated May 26, 2026

Universal Rust multiplexer with a typed SDK — drive any CLI or TUI app from code. Native on Linux, macOS, and Windows.

Rust 2,547 140 Updated Aug 5, 2026

A Python framework for self-hosted LLM tool-calling and multi-step agentic workflows

Python 2,211 171 Updated Aug 3, 2026

Fast and Accurate Code Search for Agents. Uses 99% fewer tokens than grep+read

Python 5,827 244 Updated Aug 5, 2026

codespelunker - CLI code search tool that understands code structure and ranks results by relevance. No indexing required with CLI, TUI, MCP and HTTP support.

Go 1,058 22 Updated Jul 26, 2026

Lightweight coding agent written in Rust, optimized for memory footprint and performance

Rust 1,556 120 Updated Aug 5, 2026

DeepSeek-native AI coding agent for your terminal. Engineered around prefix-cache stability — leave it running.

Go 31,508 2,026 Updated Aug 5, 2026

Deep Code 是专为 deepseek-v4 模型优化的终端 AI 编码助手,支持深度思考、推理强度控制以及 Agent Skills。

TypeScript 2,108 195 Updated Aug 4, 2026
Rust 12 Updated May 8, 2026

BAM/SAM/CRAM/FASTA reader, pileup engine, BCF/BAM writing

Rust 27 2 Updated Jun 25, 2026

Rust implementation of the Zstandard Seekable Format

Rust 277 5 Updated Aug 3, 2026

AI enabled pair programmer for Claude, GPT, O Series, Grok, Deepseek, Gemini and 300+ models

Rust 7,479 1,440 Updated Aug 5, 2026

Spiritual successor to picard for sequencing qc

Rust 57 3 Updated Jul 19, 2026

Smart(er) code reading for humans and AI agents. Reduces cost per correct answer by ~40% on average. Install: cargo install tilth -or- npx tilth

Rust 323 25 Updated Jul 25, 2026

Coding Agent singularly focused efficiency and context curation. Reduces API costs by 50-80% vs other agent AND improves the code quality at the same time. Uses Hash Anchored edits, massively paral…

TypeScript 1,442 82 Updated Aug 5, 2026

Code search MCP for Claude Code. Make entire codebase the context for any coding agent.

TypeScript 12,269 903 Updated Jul 14, 2026

A high-performance HGVS variant nomenclature parser and normalizer written in Rust

Rust 26 3 Updated Aug 5, 2026

A rust implementation of STAR

Rust 68 6 Updated Aug 5, 2026

A simple, expressive, embeddable programming language

Rust 882 47 Updated Jul 5, 2026

Lightweight, cross-platform process sandboxing powered by OpenAI Codex's runtime. Sandbox any command with file, network, and credential controls.

Rust 695 41 Updated May 17, 2026
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