The Metabolic Flux Analysis Ontology (FLUXO) is an ontology that provides a structured framework for representing concepts, relationships, and data related to metabolic flux analysis. It covers experimental design, isotopic labeling, analytical instrumentation, computational methods, and statistical analysis used in isotope-based metabolic flux analysis (I-MFA) and related fluxomics workflows.
More information can be found at http://obofoundry.org/ontology/fluxo
The latest version of the ontology can always be found at:
http://purl.obolibrary.org/obo/fluxo.owl
Editors of this ontology should use the edit version, src/ontology/fluxo-edit.owl
- Browse FLUXO terms and their definitions in the OWL edit file
- Cross-ontology mappings are available in SSSOM format
- Use the ODK build pipeline to generate release artefacts (OWL, OBO, JSON):
sh run.sh make prepare_release
These ontologies are directly imported into FLUXO and provide its foundational upper-level structure and relations:
| Ontology | Prefix | Description |
|---|---|---|
| BFO | BFO | Basic Formal Ontology |
| COB | COB | Core Ontology for Biology and Biomedicine |
| IAO | IAO | Information Artifact Ontology |
| RO | RO | Relations Ontology |
These ontologies are referenced in FLUXO's SSSOM cross-ontology mappings but are not directly imported:
| Ontology | Prefix | Description |
|---|---|---|
| CHEBI | CHEBI | Chemical Entities of Biological Interest |
| CHMO | CHMO | Chemical Methods Ontology |
| EDAM | EDAM | Ontology of bioscientific data analysis and data management |
| MSIO | MSIO | Metabolomics Standards Initiative Ontology |
| NCIT | NCIT | National Cancer Institute Thesaurus |
| nmrCV | NMR | nmrCV controlled vocabulary |
| OBI | OBI | Ontology for Biomedical Investigations |
| PATO | PATO | Phenotype And Trait Ontology |
| PREFER | PREFER | Precision Fermentation Ontology |
| SBO | SBO | Systems Biology Ontology |
| SIO | SIO | Semanticscience Integrated Ontology |
| STATO | STATO | Statistics Ontology |
| UO | UO | Units of Measurement Ontology |
Please use this GitHub repository's Issue tracker to request new terms/classes or report errors or specific concerns related to the ontology.
This ontology repository was created using the Ontology Development Kit (ODK).