Tumor Heterogeneity Index Estimating
In this package, we use the ecology methods to estimate the Tumor Heterogeneity(TH) based on their mutated loci of variant allele frequencis(VAF).
The inferHeterogeneityPlus estimate the TH based on two different methods in the Package vegan:
- Diveristy indices
- Taxonomic indices.
See also http://www.coastalwiki.org/wiki/Measurements_of_biodiversity for the concepts.
You can install the development version of THindex from GitHub with:
# install.packages("remotes")
remotes::install_github("qingjian1991/THindex")The overview of usage could be found at THindex online vignette.