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33 stars written in C
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Linux kernel source tree

C 231,309 61,975 Updated Apr 29, 2026

For developers, who are building real-time data-driven applications, Redis is the preferred, fastest, and most feature-rich cache, data structure server, and document and vector query engine.

C 74,063 24,596 Updated Apr 29, 2026

Inference Llama 2 in one file of pure C

C 19,455 2,525 Updated Aug 6, 2024

RNA-seq aligner

C 2,189 546 Updated Mar 18, 2025

A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 2,165 461 Updated Apr 25, 2026

MMseqs2: ultra fast and sensitive search and clustering suite

C 2,040 283 Updated Apr 16, 2026

Toolkit for processing sequences in FASTA/Q formats

C 1,539 328 Updated Jun 1, 2025

Near-optimal RNA-Seq quantification

C 758 181 Updated Mar 16, 2026

Sequence-to-graph mapper and graph generator

C 477 40 Updated Aug 11, 2025

Align proteins to genomes with splicing and frameshift

C 401 22 Updated Jan 5, 2026

Single-cell Transcriptome and Regulome Analysis Pipeline

C 309 79 Updated Mar 6, 2023

Pairwise whole genome aligner

C 236 16 Updated Apr 25, 2026

Constructing a pangenome gene graph

C 206 14 Updated Aug 11, 2025

UCSC command line bioinformatic utilities

C 189 96 Updated Jul 31, 2024

Yet another Hi-C scaffolding tool

C 180 20 Updated Nov 4, 2024

A simple toolset for BED files (warning: CLI may change before bedtk becomes stable)

C 144 19 Updated Aug 24, 2025

Tools to work with GWAS-VCF summary statistics files

C 136 9 Updated Feb 2, 2026

Implementation of Positional Burrows-Wheeler Transform for genetic data

C 116 42 Updated Nov 20, 2025

LongcallD: joint calling and phasing of small, structural and mosaic variants from long reads

C 104 7 Updated Apr 8, 2026

T1K is a versatile methods to genotype highly polymorphic genes (e.g. KIR, HLA) with bulk or single-cell RNA-seq, WGS or WES data.

C 99 13 Updated Dec 21, 2025

Simple pileup-based variant caller

C 95 10 Updated Apr 25, 2025

Identify long STRs, VNTRs, satellite DNA and other low-complexity regions in a genome

C 91 4 Updated Jan 28, 2026

Scoring GT/AG sites for improving spliced alignment

C 52 3 Updated Nov 10, 2025

syncmer graphs, and perhaps other sorts of sequence graphs

C 35 5 Updated Apr 1, 2026

1-code framework: docs, C-library, and tools

C 26 6 Updated Apr 2, 2026

ONEcode package to replace SAM/BAM, especially for eDNA mapping to everything

C 16 3 Updated Mar 31, 2026

We have developed a novel method named LEGO (functional Link Enrichment of Gene Ontology or gene sets). Incorporating a network-based gene-weighting scheme, LEGO measures the overlaps between the i…

C 8 4 Updated Mar 27, 2020

a regulatory potential c implementation for histone modification ChIP-seq and DNase-seq

C 4 Updated Aug 29, 2023
C 1 Updated Jan 27, 2021

A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 1 Updated Jun 19, 2023
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