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An extensible and performant aligner and read mapper

Rust 90 2 Updated Jun 7, 2026

Successor of bwa-mem for short-read alignment

C 231 7 Updated Jun 22, 2026

A GNU screen style terminal multiplexer built on libghostty.

Zig 695 20 Updated Jun 23, 2026

TermLoop workspace

Swift 33 1 Updated Jun 19, 2026

A unified interface for AI in your terminal.

Python 3,243 152 Updated May 26, 2026

Universal Rust multiplexer with a typed SDK — drive any CLI or TUI app from code. Native on Linux, macOS, and Windows.

Rust 1,871 92 Updated Jun 21, 2026

A Python framework for self-hosted LLM tool-calling and multi-step agentic workflows

Python 2,115 156 Updated Jun 20, 2026

Fast and Accurate Code Search for Agents. Uses ~98% fewer tokens than grep+read

Python 5,363 232 Updated Jun 23, 2026

codespelunker - CLI code search tool that understands code structure and ranks results by relevance. No indexing required with CLI, TUI, MCP and HTTP support.

Go 1,031 18 Updated Jun 15, 2026

Minimal coding agent written in Rust, optimized for memory footprint and performance

Rust 1,349 101 Updated Jun 22, 2026

DeepSeek-native AI coding agent for your terminal. Engineered around prefix-cache stability — leave it running.

Go 23,998 1,464 Updated Jun 23, 2026

Deep Code 是专为 deepseek-v4 模型优化的终端 AI 编码助手,支持深度思考、推理强度控制以及 Agent Skills。

TypeScript 1,289 114 Updated Jun 23, 2026
Rust 11 Updated May 8, 2026

BAM/SAM/CRAM/FASTA reader, pileup engine, BCF/BAM writing

Rust 27 2 Updated Jun 17, 2026

Rust implementation of the Zstandard Seekable Format

Rust 271 5 Updated Jun 21, 2026

AI enabled pair programmer for Claude, GPT, O Series, Grok, Deepseek, Gemini and 300+ models

Rust 7,429 1,453 Updated Jun 23, 2026

Spiritual successor to picard for sequencing qc

Rust 46 3 Updated Jun 15, 2026

Smart(er) code reading for humans and AI agents. Reduces cost per correct answer by ~40% on average. Install: cargo install tilth -or- npx tilth

Rust 295 21 Updated Jun 22, 2026

Coding Agent singularly focused efficiency and context curation. Reduces API costs by 50-80% vs other agent AND improves the code quality at the same time. Uses Hash Anchored edits, massively paral…

TypeScript 1,328 77 Updated Jun 22, 2026

Code search MCP for Claude Code. Make entire codebase the context for any coding agent.

TypeScript 11,932 887 Updated Jun 22, 2026

A high-performance HGVS variant nomenclature parser and normalizer written in Rust

Rust 24 3 Updated Jun 23, 2026

A rust implementation of STAR

Rust 49 4 Updated Jun 19, 2026

A simple, expressive, embeddable programming language

Rust 878 46 Updated Jun 8, 2026

Lightweight, cross-platform process sandboxing powered by OpenAI Codex's runtime. Sandbox any command with file, network, and credential controls.

Rust 652 39 Updated May 17, 2026

Luau bytecode interpreter for Luau

Lua 161 22 Updated Mar 8, 2026

Tool to build & run portable, lightweight, self-contained virtual machines.

Rust 3,922 179 Updated Jun 23, 2026

fastVEP: High-performance Variant Effect Predictor in Rust

Rust 103 19 Updated Jun 16, 2026

Sandbox any AI agent in seconds - zero setup, zero latency.

Rust 2,774 193 Updated Jun 22, 2026

All-in-one free/freemium/paid model providers for Pi

TypeScript 56 7 Updated Jun 22, 2026

Review-first terminal diff viewer for agentic coders

TypeScript 5,457 138 Updated Jun 22, 2026
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