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The uncompromising Python code formatter

Python 41,226 2,690 Updated Dec 12, 2025

A command-line benchmarking tool

Rust 27,035 440 Updated Dec 1, 2025

Data validation using Python type hints

Python 26,200 2,360 Updated Dec 17, 2025

Interactive Data Visualization in the browser, from Python

TypeScript 20,259 4,248 Updated Dec 17, 2025

A framework for managing and maintaining multi-language pre-commit hooks.

Python 14,708 908 Updated Dec 16, 2025

dnscrypt-proxy 2 - A flexible DNS proxy, with support for encrypted DNS protocols.

Go 12,753 1,091 Updated Dec 17, 2025

Official git repository for Biopython (originally converted from CVS)

Python 4,842 1,851 Updated Dec 15, 2025

Singularity has been renamed to Apptainer as part of us moving the project to the Linux Foundation. This repo has been persisted as a snapshot right before the changes.

Go 2,598 425 Updated Oct 10, 2022

🪼 a python library for doing approximate and phonetic matching of strings.

Jupyter Notebook 2,177 163 Updated Dec 15, 2025

A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 2,092 448 Updated Dec 12, 2025

Shiny for Python

Python 1,663 117 Updated Dec 9, 2025

Scientific workflow engine designed for simplicity & scalability. Trivially transition between one off use cases to massive scale production environments

Scala 1,041 377 Updated Dec 17, 2025

Specification for the Workflow Description Language (WDL).

840 313 Updated Nov 10, 2025

Bioinformatics containers

Dockerfile 762 261 Updated Oct 31, 2025

Plotting scripts for long read sequencing data

HTML 519 49 Updated Dec 4, 2025

a python package for fast random access to sequences from plain and gzipped FASTA/Q files

C 289 24 Updated Dec 26, 2024

pycoQC computes metrics and generates Interactive QC plots from the sequencing summary report generated by Oxford Nanopore technologies basecaller (Albacore/Guppy)

Python 284 41 Updated Oct 18, 2024

Miscellaneous collection of Python and R scripts for processing Iso-Seq data

Python 278 106 Updated Sep 26, 2023

An overview of all nanopack tools

Python 272 18 Updated Jun 2, 2023

Classifier for metagenomic sequences

C++ 268 75 Updated Jun 20, 2025

Tool for the Quality Control of Long-Read Defined Transcriptomes

HTML 250 59 Updated Dec 5, 2025

Full-Length Alternative Isoform analysis of RNA

Python 245 79 Updated Dec 12, 2025

Iso-Seq - Scalable De Novo Isoform Discovery from Single-Molecule PacBio Reads

227 62 Updated Jul 9, 2025

Workflow Description Language developer tools & local runner

Python 202 63 Updated Nov 9, 2025

Transcriptome Annotation by Modular Algorithms (for long read RNA sequencing data)

Python 166 28 Updated Apr 12, 2023

Plugins for the Ensembl Variant Effect Predictor (VEP)

Perl 162 124 Updated Dec 12, 2025

Technology agnostic long read analysis pipeline for transcriptomes

Python 154 31 Updated Jan 25, 2024

CCS: Generate Highly Accurate Single-Molecule Consensus Reads (HiFi Reads)

125 30 Updated Mar 18, 2024

Whole Genome Simulator for Next-Generation Sequencing

C 102 37 Updated Nov 24, 2025

NEAT read simulation tools

Python 101 29 Updated Jun 22, 2022
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