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18 stars written in R
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R package for integrating and analyzing multiple single-cell datasets

R 427 82 Updated Feb 4, 2026

LIANA: a LIgand-receptor ANalysis frAmework

R 238 39 Updated Aug 7, 2024

The integration of single cell rank-based gene set enrichment analysis

R 148 25 Updated Jan 14, 2026

A collection of 50+ trajectory inference methods within a common interface 📥📤

R 133 28 Updated Dec 21, 2023

R package for Pathway RespOnsive GENe activity inference

R 120 23 Updated Jan 30, 2023

Analysis of cell-cell communication at single-cell resolution

R 106 15 Updated Sep 10, 2024

Methods to compute Local Inverse Simpson's Index (LISI)

R 76 5 Updated Sep 2, 2021

Create KEGG.db Package

R 64 19 Updated Jan 29, 2026

Methods for decontamination of single cell data

R 61 7 Updated Feb 16, 2025
R 55 12 Updated Aug 1, 2024

Quantification of isoform usage and alternative polyadenylation (APA) from single-cell RNA-seq using a Nextflow-based pipeline.

R 32 3 Updated Nov 6, 2025

Calculate cluster similarity between clusters from different single cell datasets/batches/samples.

R 26 3 Updated Feb 2, 2026

Perform differential transcript usage (DTU) analysis of bulk or single-cell RNA-seq data. See documentation at:

R 22 3 Updated Mar 30, 2024

An R/Bioconductor package to identify higher-order molecular phenotypes

R 19 1 Updated Jan 15, 2024

A computation framework designed to detect differential junctions usage between two groups at single cell level

R 13 1 Updated Feb 1, 2021

A tool for quantification of alternative poly A usage

R 6 1 Updated Feb 21, 2022

This study constructs two new methods to study alternative splicing events at the single-cell level, namely DESJ-detection and AEN. DESJ-detection can detect alternative splicing differences at the…

R 4 1 Updated Aug 14, 2025