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5 stars written in C++
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Bayesian haplotype-based genetic polymorphism discovery and genotyping.

C++ 850 267 Updated May 31, 2025

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

C++ 660 225 Updated Oct 31, 2025

A set of tools written in Perl and C++ for working with VCF files, such as those generated by the 1000 Genomes Project.

C++ 538 149 Updated May 15, 2025

DRAGEN open-source mapper

C++ 178 37 Updated Sep 8, 2023

v2.x of the microassembly based somatic variant caller

C++ 23 4 Updated Jul 16, 2025