Perl-wrapper code that implements an analysis pipeline to detect transposon-based mutagenesis in cancers
deamhan: gaelic demon, devil
As with many biology-driven projects, this project was complex due to the inter-mix of basic cancer biology in mice, wet-lab sample preparation, high-throughput Next Generation Sequencing (NGS) technology, mathematical modelling and number crunching on a High Performance Compute (HPC) cluster. The devil was always in the detail, hence the project name.
The code wraps around the R-version of the Common Insertion site Mapping Platform (CIMPL) created at the Computation Cancer Biology Group, the Netherlands Cancer Institute. The code for the R implementation was uploaded to a GitHub repository in March 2017.
A description of the project was written up for the Wellcome Trust Sanger Institute's blog.
A PLACEHOLDER WHILE THE CODE GETS ROLLED INTO THE REPOSITORY