My name is Bianca Sacchi, I recently completed my PhD in the Wright lab at U of T EEB.

• 🌱 My PhD research focus was on Y chromosome degeneration and silencing in plants with very young sex chromosomes
• 🧬 I love working with complex genomes, learning new coding and bioinformatics skills, and diving into data (from frustrating data wrangling to genome visualization)
• 💻 I'm currently looking for work! Primarily interested in roles relating to bioinformatics, genomics, or biological data analysis. Also very interested in Field Applications Scientist or Customer Success-related roles with a technical/bioinformatics angle! LinkedIn
• 🤠 When I'm not troubleshooting code or reading papers you can find me bird watching 🦆, rock climbing 🧗‍♀️, or hanging out with my cat Edgar 🐈

Y chromosome degeneration in Rumex hastatulus (XYY cytotype), a plant with very young sex chromosomes

• Extensive rearrangement and ~30% Y gene loss in a <10 MYA sex chromosome
• Presenting a complete, haplotype-level assembly of a species with two Y chromosomes
• Collaboration with Zoë Humphries (TE expert)

Widespread loss of Y expression in the absence of transcriptional dosage compensation in Rumex hastatulus

• Widespread pattern of decreased Y expression relative to X expression (between gametologs)
• Increased nonsynonymous substitution rate in genes with lower Y expression
• No evidence of dosage compensation between sexes among X-linked hemizygous and silenced genes

Functional gene evolution on the Y chromosomes of Rumex hastatulus