Evaluating MSM-estimated mean first passage times

Here we will evaluate mean-first-passage-time estimates from Markov State Models and milestone-based variants. We also evaluate and propose methods for selecting the milestones.

Defining states In the future we can consider another clustering strategy accounting for uncertainties in rates: Improved coarse-graining of Markov state models via explicit consideration of statistical uncertainty http://aip.scitation.org/doi/abs/10.1063/1.4755751