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20 stars written in C++
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Open Source alternative to Algolia + Pinecone and an Easier-to-Use alternative to ElasticSearch ⚡ 🔍 ✨ Fast, typo tolerant, in-memory fuzzy Search Engine for building delightful search experiences

C++ 25,186 854 Updated Feb 6, 2026
C++ 871 67 Updated Feb 6, 2026

Hifiasm: a haplotype-resolved assembler for accurate Hifi reads

C++ 737 104 Updated Mar 18, 2025

Genome browser and variant annotation

C++ 388 10 Updated Oct 30, 2025

Scalable annotated de Bruijn graphs for DNA indexing, alignment, and assembly

C++ 217 26 Updated Feb 5, 2026

Short-read and long-read sequencing tools for diagnostics

C++ 173 34 Updated Feb 6, 2026

Low Coverage Calling of Genotypes

C++ 165 33 Updated Jan 22, 2026

Segmented HAPlotype Estimation and Imputation Tool

C++ 96 Updated Dec 5, 2025

vcfdist: Accurately benchmarking phased variant calls

C++ 84 8 Updated Sep 17, 2025

Genotype Representation Graph Library

C++ 40 4 Updated Feb 6, 2026

The Flexible Demultiplexer

C++ 39 4 Updated Jan 9, 2026
C++ 38 11 Updated Feb 6, 2026

Improving gene isoform quantification with miniQuant

C++ 32 4 Updated Jan 13, 2026

This tools counts the number of specific k-mers within sequence data. The counts can then be compare to other counts to determine to compute the probability that sample are of the same origin to di…

C++ 30 1 Updated Nov 25, 2024

Multithreaded read analysis

C++ 23 2 Updated Dec 18, 2025

v2.x of the microassembly based somatic variant caller

C++ 23 4 Updated Jul 16, 2025

xSqueezeIt VCF/BCF Genotype data compressor with extensible compute friendly format

C++ 14 2 Updated Aug 5, 2025

This is the software for FAst Marginal Epistasis test (FAME)

C++ 12 4 Updated Oct 21, 2025
C++ 6 1 Updated Sep 8, 2025