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verl: Volcano Engine Reinforcement Learning for LLMs

Python 17,630 2,854 Updated Dec 19, 2025

RAGEN leverages reinforcement learning to train LLM reasoning agents in interactive, stochastic environments.

Jupyter Notebook 2,446 194 Updated Dec 3, 2025

Derivative-Free Guidance in Diffusion Models with Soft Value-Based Decoding. For controlled generation in DNA, RNA, proteins, molecules (+ images)

Python 35 5 Updated Oct 3, 2024

Analyzing Hacker News discussions from a decade ago in hindsight with LLMs

Python 453 44 Updated Dec 10, 2025

Github repository for nanoSPLITS manuscript data and R scripts

HTML 10 1 Updated Oct 11, 2024

Analysis and method implementation for exploring private information leakage from single-cell RNA-seq count matrices

Python 4 2 Updated Aug 15, 2024

Latent Collaboration in Multi-Agent Systems

Python 611 90 Updated Dec 18, 2025
Jupyter Notebook 4 Updated Sep 26, 2025

deep residual neural network for classifying the pathogenicity of missense mutations.

Python 115 32 Updated Aug 25, 2021

A foundation model for spatial transcriptomics. It generates contextual gene representations within single cell and spatial niche.

Jupyter Notebook 9 2 Updated Aug 15, 2025

Variant-aware CRISPR off-target nomination

Python 23 9 Updated Dec 18, 2025

FlashRNA - An Efficient Model for Regulatory Genomics

Python 14 2 Updated Oct 15, 2025

Context-Aware Regularization with Markovian Integration for Attention-Based Nucleotide Analysis [NeurIPS2025]

Jupyter Notebook 5 1 Updated Nov 18, 2025
Python 14 5 Updated Mar 31, 2025

DNA sequences in a multiple sequence alignment transformer.

Jupyter Notebook 1 Updated Apr 12, 2024

A family of codon-resolution language models trained on 130 million protein-coding sequences from over 20,000 species.

Python 52 9 Updated Nov 1, 2025

OligoGym is a python package that streamlines processes involving featurization, training and evaluation of predictive models of oligonucleotide properties. Oligonucleotides include antisense oligo…

Jupyter Notebook 9 2 Updated Dec 16, 2025

DSPy: The framework for programming—not prompting—language models

Python 30,878 2,482 Updated Dec 19, 2025

An API standard for single-agent reinforcement learning environments, with popular reference environments and related utilities (formerly Gym)

Python 10,930 1,217 Updated Dec 18, 2025

Experimental design and (multi-objective) bayesian optimization.

Python 344 38 Updated Dec 18, 2025
Jupyter Notebook 5 1 Updated Apr 29, 2025
Jupyter Notebook 11 Updated Oct 10, 2024

With this snakemake pipeline you can process your MPRA sequencing data (assignment and count). It is the standard MPRA pipeline of the IGVF consortium and a further development of MPRAflow.

Python 12 7 Updated Oct 27, 2025

A portable, flexible, parallelized tool for complete processing of massively parallel reporter assay data

Python 35 16 Updated Jan 6, 2025
Python 2 Updated May 29, 2025

Multi-task and masked language model-based protein sequence embedding models.

Python 104 21 Updated Jun 16, 2021

Training setup for Langchain's Open Deep Research

Python 73 17 Updated Aug 28, 2025
Jupyter Notebook 8 1 Updated Nov 12, 2025

Methods for efficiently and accurately fitting deep models on public phenotype data.

Python 9 Updated Aug 4, 2025
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