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35 stars written in C++
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Oxford Nanopore's Basecaller

C++ 749 99 Updated Oct 21, 2025

Signal-level algorithms for MinION data

C++ 589 161 Updated Aug 5, 2023

Raw nanopore signal mapper that enables real-time targeted sequencing

C++ 530 45 Updated Mar 5, 2024

Code examples of fast and simple k-mer counters for tutorial purposes

C++ 170 16 Updated Mar 10, 2020

Fast, scalable, accessible photonic simulation

C++ 145 20 Updated Feb 8, 2025

MECAT: an ultra-fast mapping, error correction and de novo assembly tool for single-molecule sequencing reads

C++ 111 26 Updated Oct 2, 2020

An open multiple patterning framework

C++ 79 44 Updated May 17, 2024

GPU-accelerated Dynamic Time Warp (DTW) Barycenter Averaging

C++ 68 12 Updated Jul 24, 2025

A Design Rule Checker with GPU Acceleration

C++ 58 14 Updated Sep 15, 2023

Adapter trimmer for Oxford Nanopore reads using ab initio method

C++ 52 4 Updated Nov 21, 2024

Concurrent identification of m6A and m5C modifications in individual molecules from nanopore sequencing

C++ 42 3 Updated Jul 19, 2024

Fast and scalable nanopore adaptive sampling

C++ 34 2 Updated Jun 6, 2023

Software for detecting regions of BrdU and EdU incorporation in Oxford Nanopore reads.

C++ 33 15 Updated Oct 17, 2025

A streaming method for mapping nanopore raw signals

C++ 32 8 Updated Nov 7, 2021

DNA storage for nanopore sequencing using convolutional coding and basecaller-decoder integration

C++ 22 9 Updated May 28, 2023

CHAP is a tool for the functional annotation of ion channel structures:

C++ 21 10 Updated Jan 17, 2024

Workflow for Nanopore Sequencing of 10x single cell libraries

C++ 19 2 Updated Mar 20, 2025

Codec for DNA data storage able to correct substitutions, deletions, insertions and fragment loss with constraint adherence.

C++ 15 3 Updated Jan 14, 2025

Error correction scheme for storing information on DNA

C++ 12 3 Updated Jul 27, 2017

High-fidelity 5mCG DNA methylation detection model for Nanopore sequencing reads

C++ 8 Updated Jul 30, 2024

Collect raw signal event samples for k-mers from an event alignment file

C++ 8 Updated Jun 9, 2025

Signal-level algorithms for MinION data

C++ 6 Updated Oct 14, 2021

Single-molecule Workflow for Analysing RNA Modifications

C++ 6 1 Updated Oct 30, 2025

RawAlign is a real-time raw nanopore read mapper based on the Seed-Filter-Align paradigm as described by Lindegger et al. (https://arxiv.org/abs/2310.05037)

C++ 6 1 Updated Nov 2, 2023

[RECOMB-seq '25] Code repository for the paper "Efficient Trace Reconstruction for DNA Data Storage Systems using Bidirectional Beam Search"

C++ 3 Updated Apr 24, 2025

A easy-to-use CpG modification caller for Oxford Nanopore Sequencing Data

C++ 3 1 Updated Dec 24, 2024

A single-molecule manipulation instruments that utilize a magnetic field to apply force to a biomolecule-tethered magnetic bead.

C++ 3 1 Updated Mar 17, 2022

Embed fast5 signal files with a correctly formatted kmer to event alignment given the nucleotide sequence and a model file

C++ 2 Updated Sep 9, 2022

Fast signal-level matching for direct RNA nanopore sequencing

C++ 2 Updated Mar 11, 2022
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