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AutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.

Python 180,348 46,186 Updated Dec 17, 2025

🤗 Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.

Python 153,985 31,470 Updated Dec 17, 2025

GPT4All: Run Local LLMs on Any Device. Open-source and available for commercial use.

C++ 76,970 8,299 Updated May 27, 2025

Jan is an open source alternative to ChatGPT that runs 100% offline on your computer.

TypeScript 39,757 2,443 Updated Dec 17, 2025

🤗 PEFT: State-of-the-art Parameter-Efficient Fine-Tuning.

Python 20,294 2,132 Updated Dec 17, 2025

Evolutionary Scale Modeling (esm): Pretrained language models for proteins

Python 3,900 757 Updated Feb 7, 2024

Making Protein folding accessible to all!

Jupyter Notebook 2,554 682 Updated Dec 2, 2025

Open-source foundation of the user-sponsored PyMOL molecular visualization system.

C 1,532 328 Updated Dec 8, 2025

RNA sequencing analysis pipeline using STAR, RSEM, HISAT2 or Salmon with gene/isoform counts and extensive quality control.

Nextflow 1,170 828 Updated Dec 17, 2025

🧬 gget enables efficient querying of genomic reference databases

Python 1,089 80 Updated Dec 16, 2025

The next version of bwa-mem

C++ 801 117 Updated Oct 15, 2025

A Python implementation of the DESeq2 pipeline for bulk RNA-seq DEA.

Python 708 79 Updated Dec 15, 2025

Collected scripts for Pymol

Python 505 268 Updated Aug 9, 2025

🔬A library of JavaScript components to represent biological data

504 117 Updated Oct 11, 2021

Customizable workflows based on snakemake and python for the analysis of NGS data

Python 396 89 Updated Dec 11, 2025

The ViennaRNA Package

C 375 88 Updated Dec 8, 2025

Scientific Large Language Models: A Survey on Biological & Chemical Domains

346 34 Updated Sep 7, 2025

Primer3 is a command line tool to select primers for polymerase chain reaction (PCR).

C 272 70 Updated May 14, 2025

Methylation (Bisulfite-Sequencing) analysis pipeline using Bismark/bwa-meth + MethylDackel or bwa-mem + rastair

Nextflow 183 161 Updated Dec 12, 2025

tools for working with Bisulfite Sequencing data while preserving reads intrinsic dependencies

Python 176 52 Updated Dec 13, 2025

A short tutorial on how to use RSEM

139 46 Updated Apr 19, 2020

Documentation and description of AWS iGenomes S3 resource.

HTML 118 11 Updated Dec 8, 2024
Python 59 24 Updated Sep 27, 2021

An RNA manipulation library.

Python 56 33 Updated Feb 16, 2024
Python 49 18 Updated Jan 4, 2023

An R/Bioconductor package that implements a single-sample molecular phenotyping approach

R 46 6 Updated Oct 13, 2025
Python 31 7 Updated Dec 28, 2024

Python client for the Egnyte Public API.

Python 29 29 Updated Sep 4, 2025

predict stability change upon mutation

Python 28 10 Updated Jun 28, 2024

Example project for integrating igv.js and flask

Python 26 15 Updated May 17, 2025
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