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R package that automatically classifies the cells in the scRNA data by segregating non-malignant cells of tumor microenviroment from the malignant cells. It also infers the copy number profile of malignant cells, identifies subclonal structures and analyses the specific and shared alterations of each subpopulation.
Processing Salmon Alevin bootstrap replicates to account for technical uncertainty before integrating single-cell RNA-seq datasets in Seurat. Note: this project is now available as an R package: https://github.com/sbresnahan/scAmbi
MultiNicheNet: a flexible framework for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data
This repository is dedicated to curating, organizing, and annotating metadata for scRNA-seq datasets of human breast cancer, with a focus on datasets that include myeloid cells. This work is tied to the Mye-InfoBank project, aiming to enhance data integration, analysis, and reproducibility in breast cancer
CHARGE Consortium: collaboration for mapping targets from 1000G GWAS on coronary artery calcification (CAC) with Maryam Kavousi, Maxime Bos, Clint L. Miller, and Pat Peyser.
an integrative algorithm to distinguish spatially variable cell subclusters by reconstructing cells onto a pseudo space with spatial transcriptome references