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Starred repositories

55 stars written in C++
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GPT4All: Run Local LLMs on Any Device. Open-source and available for commercial use.

C++ 76,863 8,295 Updated May 27, 2025

Explorer++ is a lightweight and fast file manager for Windows

C++ 2,921 393 Updated Nov 3, 2025

An ultra-fast all-in-one FASTQ preprocessor (QC/adapters/trimming/filtering/splitting/merging...)

C++ 2,211 355 Updated Oct 14, 2025

SPAdes Genome Assembler

C++ 874 153 Updated Oct 13, 2025

The second version of the Kraken taxonomic sequence classification system

C++ 839 294 Updated Nov 5, 2025

Ultra-fast and memory-efficient (meta-)genome assembler

C++ 671 140 Updated Oct 28, 2025

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

C++ 660 225 Updated Oct 31, 2025

Mummer alignment tool

C++ 533 111 Updated Feb 4, 2025

DELLY2: Structural variant discovery by integrated paired-end and split-read analysis

C++ 490 139 Updated Nov 5, 2025

Transcript assembly and quantification for RNA-Seq

C++ 472 85 Updated Oct 22, 2025

Fast Whole-Genome Similarity (ANI) Estimation

C++ 435 69 Updated Jul 24, 2025

Fast genome and metagenome distance estimation using MinHash

C++ 424 94 Updated Sep 19, 2025

CryptSync is a small utility that synchronizes two folders while encrypting the contents in one folder. That means one of the two folders has all files unencrypted (the files you work with) and the…

C++ 424 71 Updated Dec 7, 2024

Genome browser and variant annotation

C++ 384 10 Updated Oct 30, 2025

AMRFinderPlus - Identify AMR genes and point mutations, and virulence and stress resistance genes in assembled bacterial nucleotide and protein sequence.

C++ 330 47 Updated Sep 26, 2025

🔬 Assemble large genomes using short reads

C++ 326 110 Updated Mar 27, 2025

Genome annotation with AUGUSTUS

C++ 320 116 Updated Aug 15, 2025

Bayesian haplotype-based mutation calling

C++ 319 36 Updated Oct 1, 2025

SortMeRNA: next-generation sequence filtering and alignment tool

C++ 277 65 Updated Aug 18, 2025

Program for analysing NGS data.

C++ 247 54 Updated Mar 6, 2025

a tool for CNV discovery and genotyping from depth-of-coverage by mapped reads

C++ 229 67 Updated Feb 17, 2022

A gap-closing software tool that uses long reads to enhance genome assembly.

C++ 220 16 Updated Sep 6, 2024

A tool for estimating repeat sizes

C++ 198 58 Updated Jan 30, 2024

Population-scale genotyping using pangenome graphs

C++ 193 22 Updated Jan 9, 2025

DRAGEN open-source mapper

C++ 178 37 Updated Sep 8, 2023

Control-FREEC: Copy number and genotype annotation in whole genome and whole exome sequencing data

C++ 172 51 Updated Aug 22, 2024

Short-read and long-read sequencing tools for diagnostics

C++ 168 33 Updated Nov 5, 2025

Version 5 of the CAFE phylogenetics software

C++ 148 25 Updated Feb 12, 2025

Parsnp was designed to align the core genome of hundreds to thousands of bacterial genomes within a few minutes to few hours. Input can be both draft assemblies and finished genomes, and output inc…

C++ 146 27 Updated Oct 2, 2025

iVar is a computational package that contains functions broadly useful for viral amplicon-based sequencing.

C++ 129 43 Updated Nov 3, 2025
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