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Terminal Biochem

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0% found this document useful (0 votes)
13 views16 pages

Terminal Biochem

Uploaded by

ss.webjournal
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Deta

lenminal
Galgtically mparlunt paptBles
Hemaglahta i chemiakypes andAfunction
OTace elements

6
Gcuncea btoahemical Ranciang anc de PteIon
anfestaans aÇtoro?aD
ketone bady machanfsoa.
Dabetea melßtus 3dafTioks sand metubalta changel

Labeaiky
Phelfemaf
clacstficahon anal funetioms, c pte îas
Glycogeneaia.
(8Sytheas of Heme

Ochemtosrooshe theany ce aaetdatiie phaaphoaylatis

Phenylkeaaunda
8) |LET bused an synthctie ana aetaaalftoctisn funcione
Role o Cclefum Rn mule contgacticn
0DietUny PthenL
elascmate

Ceptdes
Peptder bicondeu deived protens

Gluta4hfone
T {s wtdely spod fn natuae cind
eatsts
Fune tions Gutothfone penPorms speciolized Puncion
n enythoytes
) Tt mintcng Rac membcane Stmurtune cnd
integredy
) TE protects hemoglchln fremgttiag

Thyotopn Aaleesfng Hor mee [TR

tipepthee secreted by hy po tho lamue


EuneHen &Tt simulelepituteny glond to eleuce
Ahyrotoptn HorOOn,

hommee ef Seeeted by postenior


pitwtasy glarde It is c nanapepHde Cie ft
contuin g anmino acids)
Funcion 9 Oeyto cn causes canta ction oe ute
pegnancy hefore
panturati en to cLe loboun poin.

A0H fs also nanopephde gecmte by-pasteniox.


pttuteny glond It gtimulut kicdneys to guten watn
ond thus Pncaeuu bluod prressun,
clAssmate
Date
Pace

nqiolansing Angiotensn I is ecapepide, TH To composed

Anqfotensin 1] It hos mone hypentensie effct.


Anafotensfve 77 also ctimulofes adsien qlond

penta-peptide It gs cGmpaed
of 5 amfno errd Tt fs ound tn
boio It 9hhfbets gense o peih

nonapepide and decaepide


Baodynin ond
lealidfn nclpechvely Both acts c geut
Vago dilator, Oaocdurec from plesme
poteln y Snuke wenamn enyme

9 Antibiotic pepides (flee Attnomycin


nnatne
ond tyrocidin ane peptde

aipepHde , Abot 200 ime 5weeten


LAspante me Tt fs
used pn cold dink rousty
low-calone Sweetnen
AsL

HoTmone Gasttn and secetin cure


Gostoo frtesral
Gago- întestinal peptho ege 6er
clacsute
Date

Page

Hemogloben - chemtBay Types ond functiong

Hemoglo bfn fs e Ened coleun piq ment present pn Recs


NoTmal Ho fn blcocl R In meles2- 16 gLdl end

Hemoglabf conguglecd puotetn


Compored of Heme ghoup ana globin choun
Heme

qlobin Conuente fn amino acid and sheutiliçed

Funetiong ol omoglebis
to tissues
uemglkbi taronsorts Ge From Iungs
Hemogle bin toansportr Co, Ersn Hssue to lungs

Tgpes af Hermaglobin
HbA4 - adult Hemoglebin, compuse d ot
Heme gsup and qlabin chans, 2phaand

HbA Corm poed ot 2alphe ond2delte cheuiny

-Fetal hemoglobin
HbE
Data
Page.

struetune et hemaglebin

Ofsondeng o hemeglobfn

sRokle cell anemla


nost Commn hemuglobin disonden
The petients cells get sickie shaped and RBcs undengou
hemays
cauced by siubtion în globin cheain eoth the
alpha cheuns cue heamal bu beta chons ane abnaTnme
It con be of OHOmozyge.
OHetonoygeug muttec
only on gene fs
Homoygeus

Normal cell gickel shuped


cell
clasate
e

GAGS
LGno Coycnaglycan) ce heinapolysucchunides
Heicpelycocchrde meons Gepehg untt cf dlffenentsugar

Heicnepalyaurcheiáes one yoe ot paly sacchenide.


-pysaccnanide corme uncden cabahydte?
Caibahy eloraiee an mast abundat Pn net we mainly
compesee f cunkn, o2yy en ard hycogen Also called
higlte of calon

Heieopey cochusda use llsialed Rrto tuo type -


Omucopulyaccheonide - 74 Contin mucfn hey
slippeny n natuwne anel octs as
shock abserbent, Theynegatively
Cne

chunged and t to epe eachohen


Caenple 0 Agen @AgoTOSe ectin

ycesarmiraglycanc - Thay ane Sepeatie unfts ol disacchenidu


they ane campaed of amiro sugun and
Danic acid
g'ycosamin sugan
Laample :9Hyaucnic attd

0ualant aulprate
Heçunin
Heçunin guiphue

Ls Jscuss ihcin locatm unJ furetians.


dassnute
Date
Page

chandtin Gulpkate
Locaton Canttloge,bone, erdons
Faneiare meiintei ne chupe, Gtauctune f canilage, bone
Cnd tendan

yalunonig açia R-
LocatRon - 6en ,eyes, gonte
|Furttun - OA cts a lubioant
shock ahsorbant
wound hecaling
9 sesponihe fox cell migaztian
Compasec ot uigouauu humex and ayneval fluic

Deamatont sulphete 3
LocatfOn - 5kfn Meant valve!
Funaton mintain shape and structun e sicinen
hest velve
0eamatont Gulphe te gs aeponcble fr plugue fommutin
Pn athenesclnos

He panin
Locatien blood, lwng svin
Fune tien

Hepanih Sulphte s

Locu tion - Cel-Sunfoe Bowmann'k capsule ef glomeaulue


Fueetion- OAct onceptor Resa nziale for selective penmeeabl
ot membae
classmste
Date

keratin sulphate
kenatin sulpheate

kenetin aulphakI
Lacation CoTnea Canilage
meinteuns shepe end
Aranspenar cy ot etuctue ot cantilayc

olysacchanaiael

aDmopoly sacch nid ee Heterupolysarchanidey

mucbpolysacchunises Giycasaminaglycun

OAgan Agunnu!e
ectin Hepuin sulphate
Ochondyu in gulphete
Hyeluenic acid
keaotin ulpkete
DDeametynt sulphe te
classmate
Dote

Poge

Izoce Elemeots
mincnals penfomg uite fureton wbich ane esse ntia) foT
Ceictence cf the oxgoniso
ET Caecple - eload coogulatiar.
Acld- buse cqlibmuha
ecolcteirotion cf bonc

mncnae cae claeriEird tnto Aeuo - OPnnciple element

Mnencls

TToce elerert einciple element

micneno mec-mneas

eises lecs then

Tron,coppen, ioeine,
zne, muqnere, cabult phosphaue, Sociwm, potalaum

Truce elemente ae diidrd tnto 3type


Eentie tree elemortt
pusrible essenil tzece eloment
NAneseral Arere clemn
clAssAte
Date
Page

Let's srurrAunetions and Gounee of tTOce elemente

Iron
Total content of rRoN n humon body fe g-59m
Sounce lcaf vegetable Soto Ps paeent Pn
myaglobin ef mucle

Coppen
Sownce cenead, meat, leuy ueyetoble

mongnese Neuire Fer ormatien ep bone


COUnce ceneals, leey uegetebles

Todine Prre Seht fh thyrold qland, aynthestze thyofd


hommone
SOwnce See ferod fodizec Solt

Requ'ne fus wound heu)fing


3Ownce meat,ffeh, mile
classmate
Date
Paga

Vtcmfn D
vitamns meung uitcl t cmines
itanin Dis fat-soluble wPtamin
Vìtamih Delenmble Gtenl siucdue
And funcion 1Pke Haxmane

Soune9
Sunlght
Bocly eroluce vit Deben sein Ps eepored
prormthe sun

Eccty rsh - salmon, Tura


)
mushaoons- eporecd ensunlght
egg yalle
6 Supplene nts of vitami

Gfochemical Punetfons
phuspbate
Tncrowes fhtestinel abaoricn of calceu m ancd
Promo te calcum ne-bsorphon n led neys
medelliny
essen tial for prepen bone formaHen cncd e
and Pen tlih
Tt Pn luenee Ger hor mone pT)ducien

nole n 91ecucin concen 91isk

Defrcincy mnifesteton
Vit 0 cdepiency iS less cammn.
ntalee ot sunight epoSue cind uit o
OcCun e t n su?ei eient

ul body-Ceuen clothing fn some lEgie ns


elAssMate
Date
Page

it Ddeicieney Qcun Pn stnet vegetesien, cho nic


aleoholicsy kidney direares people
vit o lead to

Rilcets In chldren
Gone leformi ties bone so fening endplie ble bone
Bow eqs ormaten
Allealine phosphate oct fs gncmeerec

Riccets n Aute
eminenaliationof bone z bone becomes soPE
And become mome SuceepHble to fractune
clAsSMate
Date
Page

Lsaenzynes.
Linle fame o enzymel catlyin he Be me oul tion

Theyane diffeaent fn
Prn phyiceal oncd ehemiced papen ie
but penrme
Loopeniey - Ddegmee of olenatunon
0 elechaphaetie papentieg
() Tmanolcgical propentie
km anal Vmee ualu e!

Synthegineal faran dlffenent gen

Tsoenzymes et LoH laetate ehydnayenasel


LOH RS loctote odehydnogenase
Tt Rs on erídonecluctuso enzyme
T cate ly.re the îhtenconvntion f pyguvete to
laetace Pn prerente e Co-en2yme NADAOH

Ph hecunt mle
liven and l<idney

lctnice slyniicene
classate
Foge

Tsoenayme Subunt Pnineiple itse


Constituent

Heent cand
LDH

LOHa Heent and eAC

LOHa GTein and leid ney

Liver

LDH, ekeletal muele


classate
Data
Paga

Dabeltes Mlks

ele tie de eiciency of nsulfa


type -
0 TnsulPh depeneont Dinhe tee mellikuy CTYNe T1
9 Non- însulin lepenclent ofo be te melliw[TYyRTZJ

Tnsulfn dlepentent oM Nbn-Rnsuln cdependent AM


Aae -uvenile ontet oiabete Adult -ontet dieu be te
more than G y

1
Cause de eio'ny af tnaulin eitance to msultn

Due to Cuto antibaie Tnsuline levele may he nomu


aganct he panemle high
Toeetmat Inauin is the only
treetment
Ond eAReeice

ofosdeas e- 0 catasnaat Tsnowflakr cota Shart


Foocd ulcess

delyed wounel heulig


eletd cee
elAssute
Date
Page

Metabolfc changes
Oalyulu Raequnt umnyten,
crorel the n
when plasme glucare
thheshholel

aly phagia eohng


Decoeased uptake of qlucote In cellt

No qlulore leas , cell staned fr shim Hunqen cantrt


-glucore tet

Paldiprio -
Loss o uiales along uith glucose stimaes
thiret cant becewe d Jehydnu ion cuse.
palydipna

Hypenglycemfu
dy to uncontlleddebet

Gluzere tesiiy

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