COVID-19 백신 후보
IIBR-100 으로도 알려진 BriLife 는 복제 경쟁 재조합 VSV 바이러스 퇴치 COVID-19 백신 후보물질이다.[1] [2] [3] [4] 이스라엘 생물학연구소 (IIBR)가 개발했다.[1] [5] [6] IIBR은 미국 NRx 제약사와 제휴해 임상시험을 완료 하고 백신을 상용화했다.[7] [8] 햄스터를 대상으로 한 연구는 백신의 1회 복용량이 안전하고 COVID-19에 대한 보호에 효과적이라는 것을 시사했다.[9] [3]
참조 ^ a b Karpiński, Tomasz M.; Ożarowski, Marcin; Seremak-Mrozikiewicz, Agnieszka; Wolski, Hubert; Wlodkowic, Donald (1 January 2021). "The 2020 race towards SARS-CoV-2 specific vaccines" . Theranostics 11 (4): 1690–1702. doi :10.7150/thno.53691 . ISSN 1838-7640 . PMC 7778607 PMID 33408775 . ^ Bezbaruah, Rajashri; Borah, Pobitra; Kakoti, Bibhuti Bhushan; Al-Shar’I, Nizar A.; Chandrasekaran, Balakumar; Jaradat, Da’san M. M.; Al-Zeer, Munir A.; Abu-Romman, Saeid (2021). "Developmental Landscape of Potential Vaccine Candidates Based on Viral Vector for Prophylaxis of COVID-19" . Frontiers in Molecular Biosciences 8 : 96. doi :10.3389/fmolb.2021.635337 ISSN 2296-889X . PMC 8082173 PMID 33937326 . ^ a b Pushparajah, Deborah; Jimenez, Salma; Wong, Shirley; Alattas, Hibah; Nafissi, Nafiseh; Slavcev, Roderick A. (1 March 2021). "Advances in gene-based vaccine platforms to address the COVID-19 pandemic" . Advanced Drug Delivery Reviews 170 : 113–141. doi :10.1016/j.addr.2021.01.003 . ISSN 0169-409X . PMC 7789827 PMID 33422546 . ^ Venkadapathi, Jeyanthi; Govindarajan, Venkat Kumar; Sekaran, Saravanan; Venkatapathy, Santhi (9 June 2021). "A Minireview of the Promising Drugs and Vaccines in Pipeline for the Treatment of COVID-19 and Current Update on Clinical Trials" . Frontiers in Molecular Biosciences 8 : 637378. doi :10.3389/fmolb.2021.637378 ISSN 2296-889X . PMC 8219860 PMID 34179072 . ^ Clinical trial number NCT04608305 ClinicalTrials.gov ^ Scarabel, Lucia; Guardascione, Michela; Dal Bo, Michele; Toffoli, Giuseppe (1 March 2021). "Pharmacological strategies to prevent SARS-CoV-2 infection and treat the early phases of COVID-19" . International Journal of Infectious Diseases . 104 : 441–451. doi :10.1016/j.ijid.2021.01.035 . ISSN 1201-9712 . PMC 7816887 PMID 33476760 . ^ Rabinovitch, Ari; Williams, Dan (12 July 2021). Grebler, Dan (ed.). "Israel partners with NRx Pharmaceuticals to commercialize COVID vaccine" . Reuters . Retrieved 10 November 2021 . ^ "Israeli-produced vaccine shipped to Georgia for Phase II trial" . i24 News . Retrieved 10 November 2021 .^ Yahalom-Ronen, Yfat; Tamir, Hadas; Melamed, Sharon; Politi, Boaz; Shifman, Ohad; Achdout, Hagit; Vitner, Einat B.; Israeli, Ofir; Milrot, Elad; Stein, Dana; Cohen-Gihon, Inbar (16 December 2020). Shlomi Lazar, Hila Gutman, Itai Glinert, Lilach Cherry, Yaron Vagima, Shirley Lazar, Shay Weiss, Amir Ben-Shmuel, Roy Avraham, Reut Puni, Edith Lupu, Elad Bar-David, Assa Sittner, Noam Erez, Ran Zichel, Emanuelle Mamroud, Ohad Mazor, Haim Levy, Orly Laskar, Shmuel Yitzhaki, Shmuel C. Shapira, Anat Zvi, Adi Beth-Din, Nir Paran & Tomer Israely. "A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge" . Nature Communications 11 (1): 6402. doi :10.1038/s41467-020-20228-7 . ISSN 2041-1723 . PMC 7745033 PMID 33328475 . 외부 링크 위키미디어 커먼즈에는 브리라이프
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