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This repository is an exploratory resource to accelerate opensource analysis of CosMx® Spatial Molecular Imager (SMI) data. Contained here are and writeups and vignettes addressing a variety of top…

HTML 110 19 Updated Jun 11, 2026

Arch Linux Niri configuration for photography, gaming, and content creation. Features gradient borders, J.A.R.V.I.S. integration, audio routing, and comprehensive documentation.

CSS 23 Updated May 12, 2026
Python 34 3 Updated Oct 10, 2025

Package for the analysis of Transcripts outside segmented cells in ST data

Jupyter Notebook 30 2 Updated Jun 14, 2026

Variational inference for exponential family distributions as linear regression, in JAX.

Jupyter Notebook 9 1 Updated May 28, 2026

Multipurpose Gaussian Process library

Jupyter Notebook 5 1 Updated Apr 30, 2026

An extensible, state-of-the-art framework for columnar compression, and the fastest FOSS columnar file format. Formerly at @spiraldb, now an Incubation Stage project at LFAI&Data, part of the Linux…

Rust 3,006 169 Updated Jun 13, 2026

NanoGPT (124M) in 90 seconds

Python 5,392 809 Updated Jun 13, 2026

A Python toolkit for quantitative and visual quality control of segmentation and transcript assignment in spatial omics data.

Python 27 1 Updated Jun 8, 2026

Simple color conversion and perceptual (DeltaE CIE 2000) difference

Python 13 Updated Jun 8, 2026

The best ChatGPT that $100 can buy.

Python 55,006 7,497 Updated May 5, 2026

Lower-latency OpenMP-style minimalistic scoped thread-pool designed for 'Fork-Join' parallelism in Rust and C++, avoiding memory allocations, mutexes, CAS-primitives, and false-sharing on the hot p…

C++ 331 22 Updated Apr 2, 2026
Jupyter Notebook 67 19 Updated May 31, 2026

Biomni: a general-purpose biomedical AI agent

Python 3,203 595 Updated Jun 8, 2026

Genome browser and variant annotation

C++ 394 11 Updated Jun 12, 2026

A set of jupyter notebooks for the practice of TDA with the python Gudhi library together with popular machine learning and data sciences libraries.

Jupyter Notebook 472 127 Updated Mar 31, 2026

Explore genomes in the terminal. Light, blazing fast 🚀, vim-motion.

Rust 477 23 Updated Jun 14, 2026

An AI agent for spatial biology

Python 188 26 Updated May 4, 2026
Jupyter Notebook 7 2 Updated Feb 7, 2025

Generate a spatial catalogue from multiplexed imaging data

Python 19 1 Updated Jun 12, 2025

Join subcellular Visium HD bins into cells

Python 143 14 Updated May 8, 2026

Poisson-randomized gamma Poisson matrix factorization

Cython 2 3 Updated Dec 28, 2024

Simulate biological cells

Julia 23 6 Updated Oct 23, 2025

Technology-invariant pipeline for spatial omics analysis that scales to millions of cells (Xenium / Visium HD / MERSCOPE / CosMx / PhenoCycler / MACSima / etc.)

Python 280 50 Updated Jun 11, 2026

Code to reproduce analysis from Cook et al., bioRxiv, 2023

R 3 2 Updated Feb 16, 2024

Spectral unmixing of highly mixed multispectral flow and image cytometry data.

MATLAB 17 2 Updated Mar 15, 2023
Python 27 3 Updated Apr 8, 2025

Voronoi tesselations in Julia

Julia 34 8 Updated Apr 11, 2023
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