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34 stars written in C
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A code-searching tool similar to ack, but faster.

C 27,108 1,440 Updated Jun 16, 2024

C in four functions

C 10,646 1,488 Updated Dec 26, 2023

A standalone and lightweight C library

C 4,645 589 Updated Dec 22, 2025

Yank terminal output to clipboard

C 1,692 48 Updated Mar 4, 2026

Full vim for your shell (bash, zsh, gdb, python, etc)

C 1,654 36 Updated Nov 1, 2023

SRA Tools

C 1,327 279 Updated Apr 15, 2026

BWK awk modified for biological data

C 639 117 Updated Aug 11, 2022

lumpy: a general probabilistic framework for structural variant discovery

C 342 115 Updated Feb 22, 2026

A flexible framework for rapid genome analysis and interpretation

C 319 116 Updated Oct 18, 2022

UCSC Genome Browser source. "beta" is released version / "master" is testing.

C 263 99 Updated Apr 15, 2026

Program for aligning DNA sequences, a pairwise aligner.

C 243 41 Updated Mar 27, 2026

Interval data structure

C 236 33 Updated Mar 18, 2026

NCLS. Basically a static interval-tree that is silly fast for both construction and lookups. Deprecated but maintained.

C 223 24 Updated Jul 4, 2025

Fast multi-line FASTA/Q reader in several programming languages

C 177 58 Updated Jun 6, 2021

Display real time statistics of whatever you want.

C 166 25 Updated Jun 29, 2023

Basic operations on the space of numerical functions defined on the genome using lazy evaluators for flexibility and efficiency

C 154 25 Updated Nov 6, 2024

PAired-eND Assembler for DNA sequences

C 138 26 Updated Dec 21, 2020

A genotype query interface.

C 136 23 Updated Mar 29, 2021

shell tools for processing phylogenetic trees

C 119 31 Updated Aug 30, 2022

LoFreq Star: Sensitive variant calling from sequencing data

C 113 35 Updated Oct 16, 2025

BAMscale is a one-step tool for either 1) quantifying and normalizing the coverage of peaks or 2) generated scaled BigWig files for easy visualization of commonly used DNA-seq capture based methods.

C 73 17 Updated Dec 4, 2024

Exascale Maximum Likelihood (ExaML) code for phylogenetic inference using MPI

C 50 24 Updated Jun 20, 2020

Position-wise analysis of sequencing and genomics data

C 41 16 Updated Jul 6, 2023

The Dazzler Data Base

C 36 33 Updated Feb 17, 2025

python wrapper to dpryan79's bigwig library using cffi

C 19 1 Updated May 13, 2016

apache2 modules for bioinformatics.

C 18 2 Updated Sep 15, 2014

Fast but inaccurate adapter trimmer for Illumina reads

C 16 9 Updated Mar 17, 2022

a lightweight panel/taskbar, with patches

C 15 2 Updated Mar 27, 2013

NeatFreq/Automaton Reference-Free Coverage Reduction Distribution Package

C 13 2 Updated Aug 1, 2014

ChIP-seq discretization and quality control

C 9 5 Updated Apr 10, 2017
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